Search Results - "Aguila, Márcia B"
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Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet
Published in Clinical science (1979) (01-09-2010)“…The aim of the present study was to evaluate the effects of monotherapies and combinations of drugs on insulin sensitivity, adipose tissue morphology, and…”
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2
Hepatic structural alteration in adult programmed offspring (severe maternal protein restriction) is aggravated by post-weaning high-fat diet
Published in British journal of nutrition (01-12-2007)“…The present study aimed to evaluate the effects of a post-weaning high-fat (HF) diet upon hepatic morphology in rats subjected to perinatal protein…”
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3
Effects of high-fat diet on plasma lipids, adiposity, and inflammatory markers in ovariectomized C57BL/6 mice
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-03-2012)“…Abstract Objective We hypothesized that a high-fat (HF) diet aggravates ovariectomy-related complications. To test this hypothesis, ovariectomized (OVX) mice…”
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4
Maternal high-fat intake predisposes nonalcoholic fatty liver disease in C57BL/6 offspring
Published in American journal of obstetrics and gynecology (01-11-2010)“…Objective This work aimed to verify the hypothesis that maternal intake of high-fat diet in critical periods of pregnancy and/or suckling period predisposes…”
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5
Weight cycling enhances adipose tissue inflammatory responses in male mice
Published in PloS one (25-07-2012)“…Obesity is associated with low-grade chronic inflammation attributed to dysregulated production, release of cytokines and adipokines and to dysregulated…”
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Hepatic adverse effects of fructose consumption independent of overweight/obesity
Published in International journal of molecular sciences (05-11-2013)“…The chronic intake of fructose has been linked to insulin resistance, obesity, dyslipidemia and nonalcoholic fatty liver disease (NAFLD), which in turn, may…”
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Obese fathers lead to an altered metabolism and obesity in their children in adulthood: review of experimental and human studies
Published in Jornal de pediatria (01-11-2017)“…To discuss the recent literature on paternal obesity, focusing on the possible mechanisms of transmission of the phenotypes from the father to the children. A…”
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Protein restriction during gestation and/or lactation causes adverse transgenerational effects on biometry and glucose metabolism in F1 and F2 progenies of rats
Published in Clinical science (1979) (01-03-2008)“…Substantial evidence suggests that poor intrauterine milieu elicited by maternal nutritional disturbance may programme susceptibility in the fetus to later…”
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9
The inflammatory profile and liver damage of a sucrose-rich diet in mice
Published in The Journal of nutritional biochemistry (01-02-2014)“…It is still unclear if an isoenergetic, sucrose-rich diet leads to health consequences. To investigate the effects of excessive sucrose within an isoenergetic…”
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10
Rosuvastatin limits the activation of hepatic stellate cells in diet‐induced obese mice
Published in Hepatology research (01-08-2017)“…Aim The aim of this study was to investigate the effects of rosuvastatin in a model of diet‐induced obesity and non‐alcoholic fatty liver disease, with…”
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Maternal vitamin D deficiency delays glomerular maturity in F1 and F2 offspring
Published in PloS one (21-08-2012)“…There is a high prevalence of vitamin D insufficiency in women of reproductive age. This work studied the first two generations of offspring (F1 and F2) of…”
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Transgenerational Effects on the Liver and Pancreas Resulting from Maternal Vitamin D Restriction in Mice
Published in Journal of Nutritional Science and Vitaminology (2013)“…This study aimed to investigate the effects of maternal vitamin D restriction on carbohydrate metabolism and alterations in the pancreas and liver in the F1…”
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13
An early fish oil-enriched diet reverses biochemical, liver and adipose tissue alterations in male offspring from maternal protein restriction in mice
Published in The Journal of nutritional biochemistry (01-11-2011)“…Fetal programming is linked to adulthood metabolic and chronic diseases. We hypothesized that early fish oil (FO) intake would revert the programming responses…”
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14
Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01-05-2012)“…The study aimed to investigate the effect of swimming training in reducing the nonalcoholic fatty liver disease (NAFLD) and associated comorbidities, including…”
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15
Liver damage is not reversed during the lean period in diet-induced weight cycling in mice
Published in Hepatology research (01-04-2014)“…Aim Weight cycling (WC) is frequent in obesity treatment. We evaluated the degree of regression of the liver damage in WC. Methods C57BL/6 male mice received…”
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16
Fenofibrate (PPARalpha agonist) induces beige cell formation in subcutaneous white adipose tissue from diet-induced male obese mice
Published in Molecular and cellular endocrinology (15-02-2015)“…•PPARgamma has been associated with white-brown adipocyte plasticity.•We evaluated whether fenofibrate could induce beige cell depots in obese…”
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Principal components analysis on genes related to inflammasome complex and microglial activation in the hypothalamus of obese mice treated with semaglutide (GLP-1 analog)
Published in Brain research (01-01-2025)“…•Diet-induced obese (DIO) mice develop hypothalamic inflammation;•Semaglutide reduces inflammasome complex and microglial activation in DIO mice;•Semaglutide…”
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Role of dietary fish oil on nitric oxide synthase activity and oxidative status in mice red blood cells
Published in Food & function (01-12-2014)“…The consumption of n-3 polyunsaturated fatty acids (PUFAs) derived from fish oil concomitant with a reduced intake of saturated fats is associated with…”
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Cotadutide improves brown adipose tissue thermogenesis in obese mice
Published in Biochemical pharmacology (01-11-2023)“…We studied the effect of cotadutide, a dual agonist glucagon-like peptide 1 (GLP1)/Glucagon, on interscapular brown adipose tissue (iBAT) remodeling and…”
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Treating fructose-induced metabolic changes in mice with high-intensity interval training: insights in the liver, white adipose tissue, and skeletal muscle
Published in Journal of applied physiology (1985) (01-10-2017)“…Fructose-rich caloric sweeteners induce adverse changes in the metabolism of humans. The study evaluated the effects of high-intensity interval training (HIIT)…”
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