Search Results - "Aguiar, Simone Dos Santos"
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Induction therapy for acute lymphoblastic leukemia: incidence and risk factors for bloodstream infections
Published in Supportive care in cancer (2022)“…Among the treatment-related acute toxic effects, risks for bloodstream infections (BSIs) are associated with several variables. The authors carried out a…”
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Reduced hydroxymethylation characterizes medulloblastoma while TET and IDH genes are differentially expressed within molecular subgroups
Published in Journal of neuro-oncology (01-08-2018)“…Introduction Medulloblastoma (MB) is an embryonal tumour that originates from genetic deregulation of cerebellar developmental pathways and is classified into…”
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The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma
Published in Investigational new drugs (01-02-2017)“…Summary Medulloblastoma (MB) is the most common solid tumor among pediatric patients and corresponds to 20 % of all pediatric intracranial tumors in this age…”
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High-throughput microRNA profile in adult and pediatric primary glioblastomas: the role of miR-10b-5p and miR-630 in the tumor aggressiveness
Published in Molecular biology reports (01-09-2020)“…Glioblastoma (GBM) is the most common primary malignant neoplasm of the central nervous system and, despite the standard therapy; the patients’ prognoses…”
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Cisplatin and Etoposide in Childhood Germ Cell Tumor: Brazilian Pediatric Oncology Society Protocol GCT-91
Published in Journal of clinical oncology (10-03-2009)“…In 1988, we formed a consortium of Brazilian institutions to develop uniform standards for the diagnostic assessment and multidisciplinary treatment of…”
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Factors affecting diagnosis of primary pediatric central nervous system neoplasias in a developing country
Published in Child's nervous system (01-01-2019)“…Purpose Understand the variables that could interfere with diagnosis and prompt treatment in CNS childhood cancer in Brazil, a developing country with…”
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International Society of Paediatric Oncology (SIOP) Global Mapping Programme: Latin American Society of Pediatric Oncology (SLAOP) country‐level report
Published in Pediatric blood & cancer (01-06-2024)“…Background Latin American countries are improving childhood cancer care, showing strong commitment to implement the Global Initiative for Childhood Cancer, but…”
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Adherence to dental treatment reduces oral complications related to cancer treatment in pediatric and adolescent patients
Published in Supportive care in cancer (01-02-2020)“…Purpose To analyze the association between adherence to dental treatment and (1) oral complications and (2) clinical and sociodemographic aspects of pediatric…”
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Association of the highly prevalent TP53 R337H mutation with pediatric choroid plexus carcinoma and osteosarcoma in Southeast Brazil
Published in Cancer (15-05-2011)“…BACKGROUND: The inherited, low‐penetrance arginine‐to‐histidine substitution at codon 337 (R337H) of the tumor protein 53 gene (TP53) is clustered in southeast…”
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Lowered Cisplatin Dose and No Bleomycin in the Treatment of Pediatric Germ Cell Tumors: Results of the GCT-99 Protocol From the Brazilian Germ Cell Pediatric Oncology Cooperative Group
Published in Journal of clinical oncology (20-02-2016)“…We describe the results of a risk-adapted, response-based therapeutic approach from the Brazilian GCT-99 study on germ cell tumors. From May 1999 to October…”
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Downregulation of 14q32 microRNAs in Primary Human Desmoplastic Medulloblastoma
Published in Frontiers in oncology (01-01-2013)“…Medulloblastoma (MB) is one of the most common pediatric cancers, likely originating from abnormal development of cerebellar progenitor neurons. MicroRNA…”
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The novel WT1 gene mutation p.H377N associated to Denys-Drash syndrome
Published in Journal of pediatric hematology/oncology (01-08-2010)“…Denys-Drash syndrome (DDS, Online Mendelian Inheritance in Man number 194080) is a rare human developmental disease generally occurring in 46,XY individuals…”
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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
Published in Proceedings of the National Academy of Sciences - PNAS (23-12-2014)“…Osteosarcoma is the most common primary bone tumor, yet there have been no substantial advances in treatment or survival in three decades. We examined 59…”
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Comparative genomic hybridization analysis of abnormalities in chromosome 21 in childhood osteosarcoma
Published in Cancer genetics and cytogenetics (01-05-2007)“…Abstract Osteosarcomas (OS) are aggressive tumors of the bone and often have a poor prognosis. The tumors exhibit karyotypes with a high degree of complexity,…”
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LGG-51. BRAF ALTERATIONS IN PEDIATRIC LOW-GRADE GLIOMAS: RESULTS FROM A BRAZILIAN COHORT
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)Get full text
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MBRS-66. COST-EFFECTIVE METHOD TO INCORPORATE MOLECULAR CLASSIFICATION OF MEDULLOBLASTOMA INTO A LATIN-AMERICAN CLINICAL TRIAL
Published in Neuro-oncology (Charlottesville, Va.) (04-12-2020)Get full text
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Mobilization and collection of CD34+ cells for autologous transplantation of peripheral blood hematopoietic progenitor cells in children: analysis of two different granulocyte-colony stimulating factor doses
Published in Revista brasileira de hematologia e hemoterapia (01-05-2015)“…The use of peripheral hematopoietic progenitor cells (HPCs) is the cell choice in autologous transplantation. The classic dose of granulocyte-colony…”
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Abstract A41: Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
Published in Cancer research (Chicago, Ill.) (15-10-2014)“…Osteosarcoma is the most common primary bone tumor and yet there have been no substantial advances in treatment or survival in over 2 decades. We examined 59…”
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Results of a randomized prospective clinical trial evaluating maintenance chemotherapy in patients with high-grade, operable osteosarcoma: A report from the Latin American Group of Osteosarcoma Treatment
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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