Search Results - "Aguiar, Pedro Henrique Nascimento"
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A novel ABCG-like transporter of Trypanosoma cruzi is involved in natural resistance to benznidazole
Published in Memórias do Instituto Oswaldo Cruz (01-05-2015)“…Benznidazole (BZ) is one of the two drugs used for Chagas disease treatment. Nevertheless therapeutic failures of BZ have been reported, which were mostly…”
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A high-throughput colorimetric assay for detection of Schistosoma mansoni viability based on the tetrazolium salt XTT
Published in Parasites & vectors (21-06-2017)“…Schistosoma mansoni is a trematode parasite that causes schistosomiasis, one of the most prevalent neglected tropical diseases, leading to the loss of 2.6…”
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Albendazole resistance induced in Ancylostoma ceylanicum is not due to single-nucleotide polymorphisms (SNPs) at codons 167, 198, or 200 of the beta-tubulin gene, indicating another resistance mechanism
Published in Parasitology research (1987) (01-03-2019)“…Mass drug administration has been implicated as the major cause of drug resistance in nematodes of ruminants. Single-nucleotide polymorphisms (SNPs) at codons…”
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Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei and Leishmania major
Published in Journal of Nucleic Acids (01-01-2010)“…A wide variety of DNA lesions arise due to environmental agents, normal cellular metabolism, or intrinsic weaknesses in the chemical bonds of DNA. Diverse…”
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The recombinase Rad51 plays a key role in events of genetic exchange in Trypanosoma cruzi
Published in Scientific reports (06-09-2018)“…Detection of genetic exchange has been a limiting factor to deepen the knowledge on the mechanisms by which Trypanosoma cruzi is able to generate progeny and…”
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Catalase expression impairs oxidative stress-mediated signalling in Trypanosoma cruzi
Published in Parasitology (01-09-2017)“…Trypanosoma cruzi is exposed to oxidative stresses during its life cycle, and amongst the strategies employed by this parasite to deal with these situations…”
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Hookworm infection aggravates metabolic disorder in obesity
Published in Molecular and biochemical parasitology (01-09-2019)“…•Ancylostoma ceylanicum causes weight loss and decreases visceral adiposity.•A. ceylanicum aggravates the clinical condition of the obese host.•A. ceylanicum…”
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