Search Results - "Aguet, M"

VEGF is required for growth and survival in neonatal mice by Gerber, H P, Hillan, K J, Ryan, A M, Kowalski, J, Keller, G A, Rangell, L, Wright, B D, Radtke, F, Aguet, M, Ferrara, N

“…We employed two independent approaches to inactivate the angiogenic protein VEGF in newborn mice: inducible, Cre-loxP- mediated gene targeting, or…”
Get full text

The transcription factor MTF‐1 is essential for basal and heavy metal‐induced metallothionein gene expression by Heuchel, R., Radtke, F., Georgiev, O., Stark, G., Aguet, M., Schaffner, W.

“…We have described and cloned previously a factor (MTF‐1) that binds specifically to heavy metal‐responsive DNA sequence elements in the enhancer/promoter…”
Get full text

Mice devoid of PrP are resistant to scrapie by Büeler, H, Aguzzi, A, Sailer, A, Greiner, R A, Autenried, P, Aguet, M, Weissmann, C

“…S.B. Prusiner proposed that the infectious agent of scraple, the prion, is PrPSc, a modified form of the normal host protein PrPC. Prn-p0/0 mice devoid of PrPC…”
Get more information

Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase by Yang, Y. L., Reis, L. F., Pavlovic, J., Aguzzi, A., Schäfer, R., Kumar, A., Williams, B. R., Aguet, M., Weissmann, C.

“…Double‐stranded RNA‐dependent protein kinase (PKR) has been implicated in interferon (IFN) induction, antiviral response and tumor suppression. We have…”
Get full text

Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha by Flesch, I E, Hess, J H, Huang, S, Aguet, M, Rothe, J, Bluethmann, H, Kaufmann, S H

“…Interleukin 12 (IL-12) produced by macrophages immediately after infection is considered essential for activation of a protective immune response against…”
Get full text

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors by van den Broek, M F, Müller, U, Huang, S, Aguet, M, Zinkernagel, R M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The Role of Antibody Concentration and Avidity in Antiviral Protection by Bachmann, M. F., Kalinke, U., Althage, A., Freer, G., Burkhart, C., H.-P. Roost, Aguet, M., Hengartner, H., Zinkernagel, R. M.

“…Neutralizing antibodies are necessary and sufficient for protection against infection with vesicular stomatitis virus (VSV). The in vitro neutralization…”
Get full text

Mice devoid of interferon regulatory factor 1 (IRF‐1) show normal expression of type I interferon genes by Reis, L.F., Ruffner, H., Stark, G., Aguet, M., Weissmann, C.

“…The transcription factor interferon regulatory factor 1 (IRF‐1) binds tightly to the interferon (IFN)‐beta promoter and has been implicated in the induction of…”
Get full text

Interferon γ receptor deficient mice are resistant to endotoxic shock by CAR, B. D, ENG, V. M, SCHNYDER, B, OZMEN, L, SUI HUANG, GALLAY, P, HEUMANN, D, AGUET, M, RYFFEL, B

“…Antibody neutralization studies have established interferon gamma (IFN-gamma) as a critical mediator of endotoxic shock. The advent of IFN-gamma receptor…”
Get full text

Ligand-induced assembly and activation of the gamma interferon receptor in intact cells by Bach, Erika A., Tanner, J. William, Marsters, Scot, Ashkenazi, Avi, Aguet, Michel, Shaw, Andrey S., Schreiber, Robert D.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Antiviral protection by vesicular stomatitis virus-specific antibodies in alpha/beta interferon receptor-deficient mice by Steinhoff, U, Müller, U, Schertler, A, Hengartner, H, Aguet, M, Zinkernagel, R M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Role of interferon-gamma in interleukin 12-induced pathology in mice by Car, BD, Eng, VM, Schnyder, B, LeHir, M, Shakhov, AN, Woerly, G, Huang, S, Aguet, M, Anderson, TD, Ryffel, B

“…Interleukin 12 (IL-12) activates natural killer (NK) and T cells with the secondary synthesis and release of interferon-gamma (IFN-gamma) and other cytokines…”
Get full text

Development of antimalaria immunity in mice lacking IFN-gamma receptor by Tsuji, M, Miyahira, Y, Nussenzweig, RS, Aguet, M, Reichel, M, Zavala, F

“…IFN-gamma receptor deficient (IFN-gamma R-/-) mice, immunized with different developmental stages of malaria parasites, were used to define the mechanisms of…”
Get full text

The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon by Ozmen, L, Aguet, M, Trinchieri, G, Garotta, G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Generation of Nitric Oxide and Induction of Major Histocompatibility Complex Class II Antigen in Macrophages from Mice Lacking the Interferon γ Receptor by Kamijo, Ryutaro, Shapiro, Deborah, Le, Junming, Huang, Sui, Aguet, Michel, Vilcek, Jan

“…Availability of mice with a targeted disruption of the interferon γ (IFN-γ) receptor gene (IFN-γR0/0mice) made it possible to examine parameters of macrophage…”
Get full text

The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo by Eng, V M, Car, B D, Schnyder, B, Lorenz, M, Lugli, S, Aguet, M, Anderson, T D, Ryffel, B, Quesniaux, V F

“…Interleukin (IL)-12 synergizes with other cytokines to stimulate the proliferation and differentiation of early hematopoietic progenitors in vitro. However, in…”
Get full text

Purification of human γ interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human γ interferon by AGUET, M, MERLIN, G

“…mAbs against human IFN-gamma (huIFN-gamma) receptors were obtained by immunizing a BALB/c mouse with eluates from immobilized recombinant huIFN-gamma…”
Get full text

Cloning of Murine Interferon γ Receptor cDNA: Expression in Human Cells Mediates High-Affinity Binding but is not Sufficient to Confer Sensitivity to Murine Interferon γ by Hemmi, Silvio, Peghini, Pietro, Metzler, Martina, Merlin, Gilles, Dembic, Zlatko, Aguet, Michel

“…A full-length cDNA encoding the murine interferon γ (IFN-γ ) receptor was isolated from a λ gt11 library using a human IFN-γ receptor cDNA probe. The deduced…”
Get full text

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer by Delorenzi, Mauro, Farmer, Pierre, Bonnefoi, Hervé, Anderle, Pascale, Cameron, David, Wirapati, Pratyakasha, Becette, Véronique, André, Sylvie, Piccart, Martine, Campone, Mario, Brain, Etienne, MacGrogan, Gaëtan, Petit, Thierry, Jassem, Jacek, Bibeau, Frédéric, Blot, Emmanuel, Bogaerts, Jan, Aguet, Michel, Bergh, Jonas, Iggo, Richard

“…Identifying factors that influence response to cancer chemotherapy is crucial for improving its efficacy. Mauro Delorenzi and his colleagues report that a…”
Get full text

PrP-deficient mice are resistant to scrapie by Weissmann, C, Büeler, H, Fischer, M, Sailer, A, Aguzzi, A, Aguet, M

“…Prusiner proposed that the infectious agent of scrapie, the prion, is PrPSc, a modified form of the normal host protein PrPC. Prn-p0/0 mice devoid of PrPC…”
Get more information