Search Results - "Agrawal, Devendra K."

Phosphatases and kinases regulating CDC25 activity in the cell cycle: clinical implications of CDC25 overexpression and potential treatment strategies by Sur, Swastika, Agrawal, Devendra K.

“…Alterations in the cell-cycle regulatory genes result in uncontrolled cell proliferation leading to several disease conditions. Cyclin-dependent kinases (CDK)…”
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Vitamin D and its impact on maternal-fetal outcomes in pregnancy: A critical review by Agarwal, Shreya, Kovilam, Oormila, Agrawal, Devendra K.

“…The role of vitamin D beyond its classical function in calcium homeostasis has been of significant interest in recent years. There has been expanding research…”
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Key transcription factors in the differentiation of mesenchymal stem cells by Almalki, Sami G., Agrawal, Devendra K.

“…Mesenchymal stem cells (MSCs) are multipotent cells that represent a promising source for regenerative medicine. MSCs are capable of osteogenic, chondrogenic,…”
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Kawasaki disease: etiopathogenesis and novel treatment strategies by Agarwal, Shreya, Agrawal, Devendra K

“…Kawasaki disease is an acute febrile systemic vasculitis that predominantly occurs in children below five years of age. Its etiopathogenesis is still not…”
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Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance by Nandipati, Kalyana C., Subramanian, Saravanan, Agrawal, Devendra K.

“…Obesity-induced low-grade inflammation (metaflammation) impairs insulin receptor signaling. This has been implicated in the development of insulin resistance…”
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Mesenchymal stem cells and cutaneous wound healing: novel methods to increase cell delivery and therapeutic efficacy by Lee, Dylan E, Ayoub, Nagi, Agrawal, Devendra K

“…Mesenchymal stem cells (MSCs) (also known as multipotent mesenchymal stromal cells) possess the capacity for self-renewal and multi-lineage differentiation,…”
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Therapeutic Potential of Targeting the HMGB1/RAGE Axis in Inflammatory Diseases by Singh, Harbinder, Agrawal, Devendra K

“…High mobility group box 1 (HMGB1) is a nuclear protein that can interact with a receptor for advanced glycation end-products (RAGE; a multi-ligand…”
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The role of damage- and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques by Rai, Vikrant, Agrawal, Devendra K

“…Atherosclerosis is a chronic inflammatory disease resulting in the formation of the atherosclerotic plaque. Plaque formation starts with the inflammation in…”
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Effects of matrix metalloproteinases on the fate of mesenchymal stem cells by Almalki, Sami G, Agrawal, Devendra K

“…Mesenchymal stem cells (MSCs) have great potential as a source of cells for cell-based therapy because of their ability for self-renewal and differentiation…”
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Vitamin D and Bronchial Asthma: An Overview of Data From the Past 5 Years by Hall, Sannette C., BS, Agrawal, Devendra K., PhD (Biochem), PhD (MedSci), MBA

“…Abstract Purpose Vitamin D is a potent immunomodulator capable of dampening inflammatory signals in several cell types involved in the asthmatic response. Its…”
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Recent strategies in cartilage repair: A systemic review of the scaffold development and tissue engineering by Rai, Vikrant, Dilisio, Matthew F., Dietz, Nicholas E., Agrawal, Devendra K.

“…Osteoarthritis results in irreparable loss of articular cartilage. Due to its avascular nature and low mitotic activity, cartilage has little intrinsic…”
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Immunomodulation of IL-33 and IL-37 with Vitamin D in the Neointima of Coronary Artery: A Comparative Study between Balloon Angioplasty and Stent in Hyperlipidemic Microswine by Rai, Vikrant, Agrawal, Devendra K.

“…Inflammation is a major contributor to the development and progression of atherosclerosis. Interleukin (IL)-33 and IL-37, members of the IL-1 family, modulate…”
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Biomarkers for Early Detection, Prognosis, and Therapeutics of Esophageal Cancers by Rai, Vikrant, Abdo, Joe, Agrawal, Devendra K

“…Esophageal cancer (EC) is the deadliest cancer worldwide, with a 92% annual mortality rate per incidence. Esophageal squamous cell carcinoma (ESCC) and…”
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Atherothrombosis and the NLRP3 inflammasome – endogenous mechanisms of inhibition by Satish, Mohan, Agrawal, Devendra K.

“…Recently, the CANTOS (Canakinumab Anti-Inflammatory Thrombosis Outcomes Study) showed the successful anti-inflammatory benefit of canakinumab, a monoclonal…”
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Non-Coding RNAs in Regulating Plaque Progression and Remodeling of Extracellular Matrix in Atherosclerosis by Singh, Drishtant, Rai, Vikrant, Agrawal, Devendra K

“…Non-coding RNAs (ncRNAs) regulate cell proliferation, migration, differentiation, inflammation, metabolism of clinically important biomolecules, and other…”
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Relevance of mouse models of cardiac fibrosis and hypertrophy in cardiac research by Rai, Vikrant, Sharma, Poonam, Agrawal, Swati, Agrawal, Devendra K.

“…Heart disease causing cardiac cell death due to ischemia–reperfusion injury is a major cause of morbidity and mortality in the United States. Coronary heart…”
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Residual risks and evolving atherosclerotic plaques by Noothi, Sunil K., Ahmed, Mohamed Radwan, Agrawal, Devendra K.

“…Atherosclerotic disease of the coronary and carotid arteries is the primary global cause of significant mortality and morbidity. The chronic occlusive diseases…”
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Response to acute hyperglycemia and high fructose in cultured tenocytes by Kuan, Rebecca, Nath, Shilpa, Agrawal, Devendra K, Thankam, Finosh G

“…High monosaccharide levels are intimately associated with diabetes and impact tendon cells through inflammation and impairment in metabolic homeostasis…”
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Radioprotective agents to prevent cellular damage due to ionizing radiation by Smith, Tyler A, Kirkpatrick, Daniel R, Smith, Sean, Smith, Trevor K, Pearson, Tate, Kailasam, Aparna, Herrmann, Kortney Z, Schubert, Johanna, Agrawal, Devendra K

“…Medical imaging has become a central component of patient care to ensure early and accurate diagnosis. Unfortunately, many imaging modalities use ionizing…”
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Targeting the Crosstalk of Immune Response and Vascular Smooth Muscle Cells Phenotype Switch for Arteriovenous Fistula Maturation by Rai, Vikrant, Singh, Harbinder, Agrawal, Devendra K

“…Plaque formation, thrombosis, and embolism are the underlying causes of acute cardiovascular events such as myocardial infarction and stroke while early…”
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