Search Results - "Agrò, Alessandro Finazzi"

Epigenetic mechanisms and endocannabinoid signalling by D'Addario, Claudio, Di Francesco, Andrea, Pucci, Mariangela, Finazzi Agrò, Alessandro, Maccarrone, Mauro

“…The endocannabinoid system, composed of endogenous lipids, their target receptors and metabolic enzymes, has been implicated in multiple biological functions…”
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Prote‐ins by Finazzi‐Agrò, Alessandro

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Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum by Centonze, Diego, Bari, Monica, Cravatt, Benjamin F, Rossi, Silvia, Musella, Alessandra, Gasperi, Valeria, Bernardi, Giorgio, Prosperetti, Chiara, Maccarrone, Mauro, De Chiara, Valentina, Fezza, Filomena, Finazzi-Agrò, Alessandro

“…Of the endocannabinoids (eCBs), anandamide (AEA) and 2-arachidonoylglycerol (2-AG) have received the most study. A functional interaction between these…”
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The endocannabinoid system in targeting inflammatory neurodegenerative diseases by Centonze, Diego, Finazzi-Agrò, Alessandro, Bernardi, Giorgio, Maccarrone, Mauro

“…The classical divide between degenerative and inflammatory disorders of the CNS is vanishing as accumulating evidence shows that inflammatory processes are…”
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Endocannabinoids Stimulate Human Melanogenesis via Type-1 Cannabinoid Receptor by Pucci, Mariangela, Pasquariello, Nicoletta, Battista, Natalia, Di Tommaso, Monia, Rapino, Cinzia, Fezza, Filomena, Zuccolo, Michela, Jourdain, Roland, Finazzi Agrò, Alessandro, Breton, Lionel, Maccarrone, Mauro

“…We show that a fully functional endocannabinoid system is present in primary human melanocytes (normal human epidermal melanocyte cells), including anandamide…”
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p63 regulates glutaminase 2 expression by Arianna, Giacobbe, Bongiorno-Borbone, Lucilla, Bernassola, Francesca, Terrinoni, Alessandro, Markert, Elke, Levine, Arnold J., Fen, Zhaohui, Agostini, Massimiliano, Zolla, Lello, Finazzi Agro', Alessandro, Notterman, Daniel, Melino, Gerry, Peschiaroli, Angelo

“…The transcription factor p63 is critical for many biological processes, including development and maintenance of epidermal tissues and tumorigenesis. Here, we…”
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Involvement of the Endocannabinoid System in Retinal Damage after High Intraocular Pressure-Induced Ischemia in Rats by Nucci, Carlo, Gasperi, Valeria, Tartaglione, Rosanna, Cerulli, Angelica, Terrinoni, Alessandro, Bari, Monica, De Simone, Chiara, Agro, Alessandro Finazzi, Morrone, Luigi Antonio, Corasaniti, Maria Tiziana, Bagetta, Giacinto, Maccarrone, Mauro

“…To evaluate whether high intraocular pressure (IOP)-induced ischemia is associated with modifications in the retinal endocannabinoid metabolism and to…”
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In vitro and in vivo models of Huntington's disease show alterations in the endocannabinoid system by Bari, Monica, Battista, Natalia, Valenza, Marta, Mastrangelo, Nicolina, Malaponti, Marinella, Catanzaro, Giuseppina, Centonze, Diego, Finazzi‐Agrò, Alessandro, Cattaneo, Elena, Maccarrone, Mauro

“…In this study, we analyzed the components of the endocannabinoid system (ECS) in R6/2 mice, a widely used model of Huntington's disease (HD). We measured the…”
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Lung cancer identification by the analysis of breath by means of an array of non-selective gas sensors by Di Natale, Corrado, Macagnano, Antonella, Martinelli, Eugenio, Paolesse, Roberto, D'Arcangelo, Giuseppe, Roscioni, Claudio, Finazzi-Agrò, Alessandro, D'Amico, Arnaldo

“…Previous finding shown that the composition of the breath of patients with lung cancer contains information that could be used to detect the disease. These…”
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High endogenous cannabinoid levels in the cerebrospinal fluid of untreated Parkinson's disease patients by Pisani, Antonio, Fezza, Filomena, Galati, Salvatore, Battista, Natalia, Napolitano, Simone, Finazzi-Agrò, Alessandro, Bernardi, Giorgio, Brusa, Livia, Pierantozzi, Mariangela, Stanzione, Paolo, Maccarrone, Mauro

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Experimental Parkinsonism Alters Endocannabinoid Degradation: Implications for Striatal Glutamatergic Transmission by Gubellini, Paolo, Picconi, Barbara, Bari, Monica, Battista, Natalia, Calabresi, Paolo, Centonze, Diego, Bernardi, Giorgio, Finazzi-Agro, Alessandro, Maccarrone, Mauro

“…Cannabinoid receptors and their endogenous ligands have been recently identified in the brain as potent inhibitors of neurotransmitter release. Here we show…”
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Anandamide extends platelets survival through CB₁-dependent Akt signaling by Catani, Maria Valeria, Gasperi, Valeria, Evangelista, Daniela, Finazzi Agrò, Alessandro, Avigliano, Luciana, Maccarrone, Mauro

“…Platelets are stored at 22°C, since incubation at 37°C results in loss of viability. Nonetheless, in our body (37°C), platelets survive for 8-10 days. This…”
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Characterization of the Endocannabinoid System in Human Neuronal Cells and Proteomic Analysis of Anandamide-induced Apoptosis by Pasquariello, Nicoletta, Catanzaro, Giuseppina, Marzano, Valeria, Amadio, Daniele, Barcaroli, Daniela, Oddi, Sergio, Federici, Giorgio, Urbani, Andrea, Finazzi Agrò, Alessandro, Maccarrone, Mauro

“…Anandamide (AEA) is an endogenous agonist of type 1 cannabinoid receptors (CB1R) that, along with metabolic enzymes of AEA and congeners, compose the…”
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Analysis of TAp73-Dependent Signaling via Omics Technologies by D’Alessandro, Angelo, Marrocco, Cristina, Rinalducci, Sara, Peschiaroli, Angelo, Timperio, Anna Maria, Bongiorno-Borbone, Lucilla, Finazzi Agrò, Alessandro, Melino, Gerry, Zolla, Lello

“…Transactivation-proficient (TA) p73 is a transcription factor belonging to the p53 family, which regulates a variety of biological processes, including…”
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Lipid rafts regulate 2-arachidonoylglycerol metabolism and physiological activity in the striatum by Maccarrone, Mauro, De Chiara, Valentina, Gasperi, Valeria, Viscomi, Maria Teresa, Rossi, Silvia, Oddi, Sergio, Molinari, Marco, Musella, Alessandra, Finazzi-Agrò, Alessandro, Centonze, Diego

“…Several G protein-associated receptors and synaptic proteins function within lipid rafts, which are subdomains of the plasma membranes that contain high…”
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Effect of Lipid Rafts on Cb2 Receptor Signaling and 2-Arachidonoyl-Glycerol Metabolism in Human Immune Cells by Bari, Monica, Spagnuolo, Paola, Fezza, Filomena, Oddi, Sergio, Pasquariello, Nicoletta, Finazzi-Agro, Alessandro, Maccarrone, Mauro

“…Recently, we have shown that treatment of rat C6 glioma cells with the raft disruptor methyl-beta-cyclodextrin (MCD) doubles the binding of anandamide (AEA) to…”
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Estrogen stimulates arachidonoylethanolamide release from human endothelial cells and platelet activation by Maccarrone, Mauro, Bari, Monica, Battista, Natalia, Finazzi-Agrò, Alessandro

“…Estrogen replacement therapy has been associated with reduction of cardiovascular events in postmenopausal women, though the mechanism for this benefit remains…”
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Levodopa treatment reverses endocannabinoid system abnormalities in experimental parkinsonism by Maccarrone, Mauro, Gubellini, Paolo, Bari, Monica, Picconi, Barbara, Battista, Natalia, Centonze, Diego, Bernardi, Giorgio, Finazzi‐Agrò, Alessandro, Calabresi, Paolo

“…Cannabinoid receptors and their endogenous ligands are potent inhibitors of neurotransmitter release in the brain. Here, we show that in a rat model of…”
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The importance of being dimeric by Mei, Giampiero, Di Venere, Almerinda, Rosato, Nicola, Finazzi‐Agrò, Alessandro

“…Why are there so many dimeric proteins and enzymes? While for heterodimers a functional explanation seems quite reasonable, the case of homodimers is more…”
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A Critical Interaction between Dopamine D2 Receptors and Endocannabinoids Mediates the Effects of Cocaine on Striatal GABAergic Transmission by CENTONZE, Diego, BATTISTA, Natalia, ROSSI, Silvia, MERCURI, Nicola B, FINAZZI-AGRO, Alessandro, BERNARDI, Giorgio, CALABRESI, Paolo, MACCARRONE, Mauro

“…Compelling evidence indicates that endocannabinoids are implicated in drug addiction. In the present study, we have addressed the interaction between cocaine…”
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