Search Results - "Agostoni, Valentina"
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Cytokine-induced killer cells for cell therapy of acute myeloid leukemia: improvement of their immune activity by expression of CD33-specific chimeric receptors
Published in Haematologica (Roma) (01-12-2010)“…Cytokine-induced killer cells are ex vivo-expanded cells with potent antitumor activity. The infusion of cytokine-induced killer cells in patients with acute…”
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Positively charged cyclodextrins as effective molecular transporters of active phosphorylated forms of gemcitabine into cancer cells
Published in Scientific reports (21-08-2017)“…Positively charged cyclodextrins (PCCDs) are molecular carriers of particular interest for their ability to readily enter into cancer cells. Of main interest,…”
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Host–Guest Interactions in Fe(III)-Trimesate MOF Nanoparticles Loaded with Doxorubicin
Published in The journal of physical chemistry. B (24-07-2014)“…Doxorubicin (DOX) entrapment in porous Fe(III)–trimesate metal organic frameworks (MIL-100(Fe)) nanoparticles was investigated in neutral Tris buffer via…”
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A “Ship in a Bottle” Strategy To Load a Hydrophilic Anticancer Drug in Porous Metal Organic Framework Nanoparticles: Efficient Encapsulation, Matrix Stabilization, and Photodelivery
Published in Journal of medicinal chemistry (23-01-2014)“…An essential challenge in the development of nanosized metal organic framework (nanoMOF) materials in biomedicine is to develop a strategy to stabilize their…”
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Flow field-flow fractionation and multi-angle light scattering as a powerful tool for the characterization and stability evaluation of drug-loaded metal–organic framework nanoparticles
Published in Analytical and bioanalytical chemistry (01-08-2018)“…Asymmetric flow field-flow fractionation (AF4) coupled with UV-Vis spectroscopy, multi-angle light scattering (MALS) and refractive index (RI) detection has…”
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A non-covalent “click chemistry” strategy to efficiently coat highly porous MOF nanoparticles with a stable polymeric shell
Published in Biochimica et biophysica acta. General subjects (01-06-2017)“…Metal-organic framework nanoparticles (nanoMOFs) are biodegradable highly porous materials with a remarkable ability to load therapeutic agents with a wide…”
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Preclinical evaluation of liposome-supported peritoneal dialysis for the treatment of hyperammonemic crises
Published in Journal of controlled release (10-12-2020)“…Liposome-supported peritoneal dialysis (LSPD) with transmembrane pH-gradient liposomes was previously shown to enhance ammonia removal in cirrhotic rats and…”
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Efficient "green" encapsulation of a highly hydrophilic anticancer drug in metal-organic framework nanoparticles
Published in Journal of drug targeting (14-09-2015)“…Metal-organic frameworks (MOFs) are coordination polymers of interest for biomedical applications. Of particular importance, nanoparticles made of iron(III)…”
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Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions
Published in Journal of controlled release (28-05-2018)“…Peritoneal dialysis (PD) performed with transmembrane pH-gradient liposomes was reported to efficiently remove ammonia from the body, representing a promising…”
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A “green” strategy to construct non-covalent, stable and bioactive coatings on porous MOF nanoparticles
Published in Scientific reports (21-01-2015)“…Nanoparticles made of metal-organic frameworks (nanoMOFs) attract a growing interest in gas storage, separation, catalysis, sensing and more recently,…”
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β-Cyclodextrin polymer nanoparticles as carriers for doxorubicin and artemisinin: a spectroscopic and photophysical study
Published in Photochemical & photobiological sciences (01-08-2012)“…The association of doxorubicin (DOX) and artemisinin (ART) to a β-CyD-epichlorohydrin crosslinked polymer (pβ-CyD), organized in nanoparticles of ca. 15 nm…”
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Liposome-Supported Peritoneal Dialysis for the Treatment of Hyperammonemia-Associated Encephalopathy
Published in Advanced functional materials (13-12-2016)“…Hyperammonemia can lead to cerebral dysfunction, encephalopathy, coma, and death if not treated adequately. The poor prognosis associated with this condition…”
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Towards an Improved anti-HIV Activity of NRTI via Metal-Organic Frameworks Nanoparticles
Published in Advanced healthcare materials (01-12-2013)“…Nanoscale mesoporous iron carboxylates metal–organic frameworks (nanoMOFs) have recently emerged as promising platforms for drug delivery, showing…”
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SuO015VS-01 - A PROMISING INTRAPERITONEAL TREATMENT TO MANAGE HEPATIC ENCEPHALOPATHY AND RENAL FAILURE IN CIRRHOTIC PATIENTS
Published in Nephrology, dialysis, transplantation (01-05-2018)Get full text
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In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor
Published in Blood (05-05-2011)“…Chronic lymphocytic leukemia (CLL) is characterized by an accumulation of mature CD19+CD5+CD20dim B lymphocytes that typically express the B-cell activation…”
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Hyperammonemia: Liposome-Supported Peritoneal Dialysis for the Treatment of Hyperammonemia-Associated Encephalopathy (Adv. Funct. Mater. 46/2016)
Published in Advanced functional materials (01-12-2016)“…On page 8382, J.‐C. Leroux and co‐workers describe a novel approach for treating hyperammonemia induced encephalopathy, based on the peritoneal infusion of…”
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Upregulation of adhesion molecules on leukemia targets improves the efficacy of cytotoxic T cells transduced with chimeric anti-CD19 receptor
Published in Journal of immunotherapy (1997) (01-04-2013)“…T lymphocytes engineered to express chimeric antigen receptors (CARs) interact directly with cell surface molecules, bypassing MHC antigen presentation…”
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In Vitro Comparison of Three Different Chimeric Receptor-modified Effector T-cell Populations for Leukemia Cell Therapy
Published in Journal of immunotherapy (1997) (01-07-2011)“…The identification of the optimal T-cell effector subtype is a crucial issue for adoptive cell therapy with chimeric receptor-modified T cells. The ideal T…”
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A New Chimeric Antigen Receptor (CAR) Targeting the CD23 Antigen Expressed by Chronic Lymphocytic Leukemia (B-CLL) Cells
Published in Blood (19-11-2010)“…Abstract 2446 B-Chronic lymphocytic leukemia (B-CLL) is characterized by a progressive accumulation of B-lymphocytes expressing CD19, CD20dim and aberrantly…”
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