Search Results - "Agostinone, Jessica"
-
1
Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells
Published in Gene therapy (01-06-2021)“…Small and cell-type restricted promoters are important tools for basic and preclinical research, and clinical delivery of gene therapies. In clinical gene…”
Get full text
Journal Article -
2
AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
Published in Molecular neurodegeneration (29-06-2021)“…The maintenance of complex dendritic arbors and synaptic transmission are processes that require a substantial amount of energy. Bioenergetic decline is a…”
Get full text
Journal Article -
3
Insulin signalling promotes dendrite and synapse regeneration and restores circuit function after axonal injury
Published in Brain (London, England : 1878) (01-07-2018)“…See Peterson and Benowitz (doi:10.1093/brain/awy165) for a scientific commentary on this article. Dendrites retract and disconnect from their cellular partners…”
Get full text
Journal Article -
4
An Antagonistic Axon-Dendrite Interplay Enables Efficient Neuronal Repair in the Adult Zebrafish Central Nervous System
Published in Molecular neurobiology (01-05-2019)“…Neural insults and neurodegenerative diseases typically result in permanent functional deficits, making the identification of novel pro-regenerative molecules…”
Get full text
Journal Article -
5
Retinal ganglion cell dendrite pathology and synapse loss: Implications for glaucoma
Published in Progress in brain research (2015)“…Dendrites are exquisitely specialized cellular compartments that critically influence how neurons collect and process information. Retinal ganglion cell (RGC)…”
Get more information
Journal Article -
6
New MiniPromoter Ple345 (NEFL) Drives Strong and Specific Expression in Retinal Ganglion Cells of Mouse and Primate Retina
Published in Human gene therapy (01-03-2019)“…Retinal gene therapy is leading the neurological gene therapy field, with 32 ongoing clinical trials of recombinant adeno-associated virus (rAAV)-based…”
Get more information
Journal Article