Search Results - "Agostinho, P"
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1
Unsupervised analysis of whole transcriptome data from human pluripotent stem cells cardiac differentiation
Published in Scientific reports (07-02-2024)“…The main objective of the present work was to highlight differences and similarities in gene expression patterns between different pluripotent stem cell…”
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2
Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades
Published in Neuroscience (28-10-2008)“…Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily characterized by excessive deposition of amyloid-β (Aβ) peptides in the…”
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3
Spatial memory impairments in a prediabetic rat model
Published in Neuroscience (10-10-2013)“…Highlights • Short- and long-term spatial memory deficits are present in prediabetic rats. • Memory deficits are concurrent with increases of GluA1 and GLUN1…”
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4
Towards a diversified agricultural forest-based economy: Community views of planting sandalwood in Timor-Leste
Published in Forest and Society Online (01-11-2023)“…With growing awareness that export revenues derived from non-renewable oil and gas resources are in decline, Timor-Leste seeks to develop a more sustainable…”
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5
Functional interaction between pre‐synaptic α6β2‐containing nicotinic and adenosine A2A receptors in the control of dopamine release in the rat striatum
Published in British journal of pharmacology (01-08-2013)“…Background and Purpose Pre‐synaptic nicotinic ACh receptors (nAChRs) and adenosine A2A receptors (A2ARs) are involved in the control of dopamine release and…”
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6
Age-related changes in the synaptic density of amyloid-b protein precursor and secretases in the human cerebral cortex
Published in European neuropsychopharmacology (01-10-2016)Get full text
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7
Cell cycle re-entry in Alzheimer's disease: a major neuropathological characteristic?
Published in Current Alzheimer research (01-06-2009)“…Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills. With over 26 million patients in 2006,…”
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8
Alzheimer's disease-associated neurotoxic mechanisms and neuroprotective strategies
Published in Current drug targets. CNS & neurological disorders (01-08-2005)“…The characteristic hallmarks of Alzheimer's disease (AD), the most common form of dementia in the elderly, include senile plaques, mainly composed of…”
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9
Neurodegenerative pathways in Parkinson's disease: therapeutic strategies
Published in Current drug targets. CNS & neurological disorders (01-08-2005)“…Parkinson's disease (PD), considered one of the major neurological disorders, is characterized by the loss of dopaminergic neurons in the pars compacta of the…”
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10
Informing a Behavior Change Communication Strategy: Formative Research Findings From the Scaling Up Nutrition Movement in Mozambique
Published in Food and nutrition bulletin (01-09-2015)“…Background: Nutrition interventions targeting the first 1000 days show promise to improve nutritional status, but they require effective implementation…”
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11
Susceptibility of hippocampal neurons to Aβ peptide toxicity is associated with perturbation of Ca2+ homeostasis
Published in Brain research (01-04-2007)“…Abstract Neuritic dystrophy, loss of synapses and neuronal death in the cerebral cortex and hippocampus are hallmarks of Alzheimer's disease. The aim of the…”
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12
Vinpocetine attenuates the metabolic dysfunction induced by amyloid beta-peptides in PC12 cells
Published in Free radical research (01-01-2000)“…The cytoprotective effect of vinpocetine [14-ethoxycarbonyl-(3alpha, 16alpha-ethyl)-14,15-eburnamine] was investigated on PC12 cells treated with the amyloid…”
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13
P418Cine short-axis image quality optimisation on 3T cardiac MR
Published in European heart journal cardiovascular imaging (01-06-2019)Get full text
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14
Towards a diversified agricultural forest-based economy: Community views of planting sandalwood in Timor-Leste
Published in Forest and Society Online (01-09-2023)“…With growing awareness that export revenues derived from non-renewable oil and gas resources are in decline, Timor-Leste seeks to develop a more sustainable…”
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15
P.5.e.001 - Age-related changes in the synaptic density of amyloid-b protein precursor and secretases in the human cerebral cortex
Published in European neuropsychopharmacology (01-10-2016)Get full text
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16
Overexpression of UCP1 in tobacco induces mitochondrial biogenesis and amplifies a broad stress response
Published in BMC plant biology (28-05-2014)“…Uncoupling protein one (UCP1) is a mitochondrial inner membrane protein capable of uncoupling the electrochemical gradient from adenosine-5'-triphosphate (ATP)…”
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17
Oxidative stress affects the selective ion permeability of voltage-sensitive Ca 2+ channels in cultured retinal cells
Published in Neuroscience research (1997)“…The effect of ascorbate/Fe 2+-induced oxidative stress on the intracellular Ca 2+ concentration ([Ca 2+] i) and on the voltage-sensitive Ca 2+ channels (VSCC)…”
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18
A rare case of multiple variants of porokeratosis in the same patient: The clue of dermoscopy for diagnosis and therapeutical update
Published in Dermatologic therapy (01-05-2020)“…Porokeratosis (PK) consists of abnormal keratinization of the epidermis of uncertain etiology and was first described by Mibelli in 1893. Multiple clinical…”
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Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-β Levels in Patients with Alzheimer's Disease?
Published in Journal of Alzheimer's disease (01-01-2015)“…Caffeine may be protective against Alzheimer's disease (AD) by modulating amyloid-β (Aβ) metabolic pathways. The present work aimed to study a possible…”
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Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide
Published in Neuroscience research (2003)“…Acetylcholinesterase (AChE) activity is increased within and around amyloid plaques, which are present in Alzheimer's disease (AD) patient's brain. In this…”
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