Search Results - "Agnew, William"

Over-pulsing degrades activated iridium oxide films used for intracortical neural stimulation by Cogan, Stuart F, Guzelian, Andrew A, Agnew, William F, Yuen, Ted G.H, McCreery, Douglas B

“…Microelectrodes using activated iridium oxide (AIROF) charge-injection coatings have been pulsed in cat cortex at levels from near-threshold for neural…”
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A profile of alternative RNA splicing and transcript variation of CACNA1H, a human T-channel gene candidate for idiopathic generalized epilepsies by Zhong, Xiaoli, Liu, Jinrong R., Kyle, John W., Hanck, Dorothy A., Agnew, William S.

“…Highly alternatively spliced genes may provide complex targets for disease mutations. Structural changes created by missense mutations may differentially…”
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Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations by Emerick, Mark C, Stein, Rebecca, Kunze, Robin, McNulty, Megan M, Regan, Melissa R, Hanck, Dorothy A, Agnew, William S

“…We describe the regulated transcriptome of CACNA1G, a human gene for T-type Ca(v)3.1 calcium channels that is subject to extensive alternative RNA splicing…”
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Multivariate analysis and visualization of splicing correlations in single-gene transcriptomes by Emerick, Mark C, Parmigiani, Giovanni, Agnew, William S

“…RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with…”
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Evaluation of the stability of intracortical microelectrode arrays by Xindong Liu, McCreery, D.B., Bullara, L.A., Agnew, W.F.

“…In order to use recorded neural activities from the brain as control signals for neuroprosthesis devices, it is important to maintain a stable interface…”
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Protocol for the longitudinal study of neuroinflammation and reactive astrocytes in Lcn2CreERT2 mice by Ubina, Teresa, Agnew-Svoboda, William, Figueroa, Zoe A., Wilson, Emma H., Fiacco, Todd A., Riccomagno, Martin M.

“…During brain disease, astrocytes can reprogram into a reactive state that alters many of their functions. Here, we present a protocol for studying…”
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The effect of higher order RNA processes on changing patterns of protein domain selection: A developmentally regulated transcriptome of type 1 inositol 1,4,5-trisphosphate receptors by Regan, Melissa R., Lin, Doris D.M., Emerick, Mark C., Agnew, William S.

“…The domain structure of proteins synthesized from a single gene can be remodeled during tissue development by activities at the RNA level of gene expression…”
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The effects of prolonged intracortical microstimulation on the excitability of pyramidal tract neurons in the cat by McCreery, Douglas B, Agnew, William F, Bullara, Leo A

“…This study was conducted to examine the excitability changes induced in cerebral cortical neurons during prolonged microstimulation with a spatially dense…”
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The Type 1 Inositol 1,4,5-Trisphosphate Receptor Gene Is Altered in the opisthotonos Mouse by Street, Valerie A, Bosma, Martha M, Demas, Vasiliki P, Regan, Melissa R, Lin, Doras D, Robinson, Linda C, Agnew, William S, Tempel, Bruce L

“…The opisthotonos (opt) mutation arose spontaneously in a C57BL/Ks-db2J colony and is the only known, naturally occurring allele of opt. This mutant mouse was…”
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AI Ethics and Critique for Robotics by Agnew, William

“…In this thesis I consider using 3D computer vision for social good. In particular, I present a broad and deep array of AI ethics methodologies and practices…”
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The effects of instructional method on fourth-grade reading achievement: Phonics versus a balanced approach in language arts instruction by Agnew, William Thomas

“…Purpose, scope, and method of study. This study compared reading achievement between two groups of students in Christian schools: one used a phonics approach,…”
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Histopathologic and Physiologic Effects of Chronic Implantation of Microelectrodes in Sacral Spinal Cord of the Cat by Woodford, Barbara J, Carter, Randy R, McCreery, Douglas, Bullara, Leo A, Agnew, William F

“…Active microelectrodes were implanted for a period of 2 weeks to 3 months into the sacral spinal cord of 10 male cats in order to test the feasibility and the…”
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Primary structure and functional expression of a mammalian skeletal muscle sodium channel by Trimmer, J S, Cooperman, S S, Tomiko, S A, Zhou, J Y, Crean, S M, Boyle, M B, Kallen, R G, Sheng, Z H, Barchi, R L, Sigworth, F J

“…We describe the isolation and characterization of a cDNA encoding the alpha subunit of a new voltage-sensitive sodium channel, microI, from rat skeletal…”
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Serine-1321-Independent Regulation of the μ1 Adult Skeletal Muscle Na+Channel by Protein Kinase C by Said Bendahhou, Theodore R. Cummins, Jerald F. Potts, Jiefei Tong, William S. Agnew

“…The adult skeletal muscle Na+channel μ 1 possesses a highly conserved segment between subunit domains III and IV containing a consensus protein kinase C (PKC)…”
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Principal glycopeptide of the tetrodotoxin/saxitoxin binding protein from Electrophorus electricus: isolation and partial chemical and physical characterization by Miller, James A, Agnew, William S, Levinson, Simon R

“…Preparations of the tetrodotoxin (TTX) and saxitoxin binding protein isolated from the electroplax of Electrophorus electricus are of high specific activity…”
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Evolution and resolution of stimulation-induced axonal injury in peripheral nerve by Agnew, William F., McCreery, Douglas B., Yuen, Ted G. H., Bullara, Leo A.

“…We describe the evolution of axonal injury following the induction of neural damage by electrical stimulation. The sciatic nerves of cats were stimulated…”
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Proteins that bridge the gap by Agnew, William S

“…A report on what the molecular steps are by which electrical impulses induced on the surface of a muscle cell are converted to precisely controlled physical…”
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Design of Cardiovascular Energy Harvesting Devices by Agnew, William James

“…Two fields of cardiovascular energy harvesting are investigated, (1) stents and (2) leadless pacemaker. The demand for rechargeable technologies in…”
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Cloning of the SR foot by Agnew, William S

“…The cloning of the foot process of the sarcoplasmic reticulum (SR), a molecule associated with ion transport, is discussed. In muscle fibers, this molecule…”
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Profiling the array of Cav3.1 variants from the human T-type calcium channel gene CACNA1G: Alternative structures, developmental expression, and biophysical variations by Emerick, Mark C., Stein, Rebecca, Kunze, Robin, McNulty, Megan M., Regan, Melissa R., Hanck, Dorothy A., Agnew, William S.

“…We describe the regulated transcriptome of CACNA1G, a human gene for T‐type Cav3.1 calcium channels that is subject to extensive alternative RNA splicing…”
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