Search Results - "Agnès, Veyradier"

Thrombotic thrombocytopenic purpura by Joly, Bérangère S., Coppo, Paul, Veyradier, Agnès

“…Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe…”
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Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19 by Joly, Bérangère S., Siguret, Virginie, Veyradier, Agnès

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A new drug for an old concept: aptamer to von Willebrand factor for prevention of arterial and microvascular thrombosis by Veyradier, Agnès

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Von Willebrand Factor — A New Target for TTP Treatment? by Veyradier, Agnès

“…Thrombotic thrombocytopenic purpura (TTP), a rare thrombotic microangiopathy, is defined by a mechanical hemolytic anemia, severe thrombocytopenia, and…”
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Management of thrombotic microangiopathy in pregnancy and postpartum: report from an international working group by Fakhouri, Fadi, Scully, Marie, Provôt, François, Blasco, Miquel, Coppo, Paul, Noris, Marina, Paizis, Kathy, Kavanagh, David, Pène, Frédéric, Quezada, Sol, Hertig, Alexandre, Kissling, Sébastien, O'Brien, Patrick, Delmas, Yahsou, Alberio, Lorenzo, Winer, Norbert, Veyradier, Agnès, Cataland, Spero, Frémeaux-Bacchi, Véronique, Loirat, Chantal, Remuzzi, Giuseppe, Tsatsaris, Vassilis

“…Pregnancy and postpartum are high-risk periods for different forms of thrombotic microangiopathy (TMA). However, the management of pregnancy-associated TMA…”
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Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID‐19 patients by Joly, Bérangère S., Darmon, Michael, Dekimpe, Charlotte, Dupont, Thibault, Dumas, Guillaume, Yvin, Elise, Beranger, Nicolas, Vanhoorelbeke, Karen, Azoulay, Elie, Veyradier, Agnès

“…Background Critically ill patients with coronavirus disease 2019 (COVID‐19) are prone to developing macrothrombosis and microthrombosis. COVID‐19 has been…”
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A regimen with caplacizumab, immunosuppression, and plasma exchange prevents unfavorable outcomes in immune-mediated TTP by Coppo, Paul, Bubenheim, Michael, Azoulay, Elie, Galicier, Lionel, Malot, Sandrine, Bigé, Naïke, Poullin, Pascale, Provôt, François, Martis, Nihal, Presne, Claire, Moranne, Olivier, Benainous, Ruben, Dossier, Antoine, Seguin, Amélie, Hié, Miguel, Wynckel, Alain, Delmas, Yahsou, Augusto, Jean-François, Perez, Pierre, Rieu, Virginie, Barbet, Christelle, Lhote, François, Ulrich, Marc, Rumpler, Anne Charvet, de Witte, Sten, Krummel, Thierry, Veyradier, Agnès, Benhamou, Ygal

“…The anti–von Willebrand factor nanobody caplacizumab was licensed for adults with immune-mediated thrombotic thrombocytopenic purpura (iTTP) based on…”
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Unexpected frequency of Upshaw-Schulman syndrome in pregnancy-onset thrombotic thrombocytopenic purpura by Moatti-Cohen, Marie, Garrec, Céline, Wolf, Martine, Boisseau, Pierre, Galicier, Lionel, Azoulay, Elie, Stepanian, Alain, Delmas, Yahsou, Rondeau, Eric, Bezieau, Stéphane, Coppo, Paul, Veyradier, Agnès

“…Pregnancy may be complicated by a rare but life-threatening disease called thrombotic thrombocytopenic purpura (TTP). Most cases of TTP are due to an acquired…”
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Preemptive rituximab infusions after remission efficiently prevent relapses in acquired thrombotic thrombocytopenic purpura by Hie, Miguel, Gay, Julie, Galicier, Lionel, Provôt, François, Presne, Claire, Poullin, Pascale, Bonmarchand, Guy, Wynckel, Alain, Benhamou, Ygal, Vanhille, Philippe, Servais, Aude, Bordessoule, Dominique, Coindre, Jean-Philippe, Hamidou, Mohamed, Vernant, Jean-Paul, Veyradier, Agnès, Coppo, Paul

“…In acquired thrombotic thrombocytopenic purpura (TTP), the persistence of severe ADAMTS13 deficiency (<10%) during remission is associated with more relapse…”
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ADAMTS13 conformation is closed in non-immune acquired thrombotic thrombocytopenic purpura of unidentified pathophysiology by Joly, Bérangère S, Roose, Elien, Coppo, Paul, Vanhoorelbeke, Karen, Veyradier, Agnès

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ADAMTS13 Gene Mutations Influence ADAMTS13 Conformation and Disease Age-Onset in the French Cohort of Upshaw-Schulman Syndrome by Joly, Bérangère S, Boisseau, Pierre, Roose, Elien, Stepanian, Alain, Biebuyck, Nathalie, Hogan, Julien, Provot, François, Delmas, Yahsou, Garrec, Céline, Vanhoorelbeke, Karen, Coppo, Paul, Veyradier, Agnès

“…Congenital thrombotic thrombocytopaenic purpura (TTP) or Upshaw-Schulman syndrome (USS) is a rare, life-threatening, inherited thrombotic microangiopathy…”
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Immune-mediated thrombotic thrombocytopenic purpura following COVID-19 vaccination by Picod, Adrien, Rebibou, Jean-Michel, Dossier, Antoine, Cador, Bérengère, Ribes, David, Vasco-Moynet, Claire, Stephan, Caroline, Bellal, Mathieu, Wynckel, Alain, Poullin, Pascale, Péju, Edwige, Ricard, Laure, Kahn, Jean-Emmanuel, Bouzid, Raïda, Benhamou, Ygal, Joly, Bérangère, Veyradier, Agnès, Coppo, Paul

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Epidemiology and pathophysiology of adulthood-onset thrombotic microangiopathy with severe ADAMTS13 deficiency (thrombotic thrombocytopenic purpura): a cross-sectional analysis of the French national registry for thrombotic microangiopathy by Mariotte, Eric, MD, Azoulay, Elie, Prof, Galicier, Lionel, MD, Rondeau, Eric, Prof, Zouiti, Fouzia, MD, Boisseau, Pierre, PhD, Poullin, Pascale, MD, de Maistre, Emmanuel, MD, Provôt, François, MD, Delmas, Yahsou, MD, Perez, Pierre, MD, Benhamou, Ygal, MD, Stepanian, Alain, PhD, Coppo, Paul, Prof, Veyradier, Agnès, Prof

“…Summary Background Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy related to a severe deficiency of ADAMTS13 (a disintegrin and…”
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Acquired thrombotic thrombocytopenic purpura without detectable anti-ADAMTS13 antibodies: a possible underlying autoimmune mechanism by Simon, Delphine, Leclercq, Mathilde, Joly, Bérangère, Veyradier, Agnès, Coppo, Paul, Benhamou, Ygal

“…In up to 25% of patients with acquired TTP, anti-ADAMTS13 antibodies are not identified, the mechanism resulting from ADAMTS13 deficiency remains unidentified…”
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Coagulation disorders in patients with severe hemophagocytic lymphohistiocytosis by Valade, Sandrine, Joly, Bérangère S, Veyradier, Agnès, Fadlallah, Jehane, Zafrani, Lara, Lemiale, Virginie, Launois, Amélie, Stepanian, Alain, Galicier, Lionel, Fieschi, Claire, Mirouse, Adrien, Tudesq, Jean Jacques, Lepretre, Anne-Claire, Azoulay, Elie, Darmon, Michael, Mariotte, Eric

“…Background Coagulation disorders are common in patients with hemophagocytic lymphohistiocytosis (HLH), associated with an increased risk of bleeding and death…”
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Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers by Hrdinová, Johana, D'Angelo, Silvia, Graça, Nuno A G, Ercig, Bogac, Vanhoorelbeke, Karen, Veyradier, Agnès, Voorberg, Jan, Coppo, Paul

“…Although outstanding progress has been made in understanding the pathophysiology of thrombotic thrombocytopenic purpura (TTP), knowledge of the…”
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N-glycan–mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP by Ercig, Bogac, Graça, Nuno A.G., Kangro, Kadri, Arfman, Tom, Wichapong, Kanin, Hrdinová, Johana, Kaijen, Paul, van Alphen, Floris P.J., van den Biggelaar, Maartje, Vanhoorelbeke, Karen, Veyradier, Agnès, Coppo, Paul, Reutelingsperger, Chris, Nicolaes, Gerry A.F., Männik, Andres, Voorberg, Jan

“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is an autoimmune disorder caused by the development of autoantibodies targeting different domains of…”
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Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center by FROISSART, Antoine, BUFFET, Marc, BORDESSOULE, Dominique, GUIDET, Bertrand, AZOULAY, Elie, MARIOTTE, Eric, RONDEAU, Eric, MIRA, Jean-Paul, WYNCKEL, Alain, CLABAULT, Karine, CHOUKROUN, Gabriel, PRESNE, Claire, VEYRADIER, Agnès, POURRAT, Jacques, HAMIDOU, Mohamed, COPPO, Paul, POULLIN, Pascale, PROVOT, François, MALOT, Sandrine, SCHWARZINGER, Michael, GALICIER, Lionel, VANHILLE, Philippe, VEMANT, Jean-Paul

“…To assess the efficacy and safety of rituximab in adults responding poorly to standard treatment for severe autoimmune thrombotic thrombocytopenic purpura…”
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Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura by Graça, Nuno A G, Ercig, Bogac, Carolina Velásquez Pereira, Leydi, Kangro, Kadri, Kaijen, Paul, Nicolaes, Gerry A F, Veyradier, Agnès, Coppo, Paul, Vanhoorelbeke, Karen, Männik, Andres, Voorberg, Jan

“…Antibodies that develop in patients with immune thrombotic thrombocytopenic purpura (iTTP) commonly target the spacer epitope R568/F592/R660/Y661/Y665 (RFRYY)…”
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HLA-DRB111 is a strong risk factor for acquired thrombotic thrombocytopenic purpura in children by Joly, Bérangère S, Loiseau, Pascale, Darmon, Michael, Leblanc, Thierry, Chambost, Hervé, Fouyssac, Fanny, Guigonis, Vincent, Harambat, Jérôme, Stepanian, Alain, Coppo, Paul, Veyradier, Agnès

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