Search Results - "Aglione, Johnpaul"
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A cynomolgus monkey E. coli urinary tract infection model confirms efficacy of new FimH vaccine candidates
Published in Infection and immunity (15-10-2024)“…The increase in urinary tract infections (UTI) caused by antibiotic-resistant requires the development of new therapeutic agents and prophylactic vaccines. To…”
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Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys
Published in Endocrinology (Philadelphia) (01-08-2015)“…Antagonizing glucagon action represents an attractive therapeutic option for reducing hepatic glucose production in settings of hyperglycemia where glucagon…”
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Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice
Published in Endocrinology (Philadelphia) (01-12-2015)“…Secreted frizzled-related protein 4 (SFRP4) is an extracellular regulator of the wingless-type mouse mammary tumor virus integration site family (WNT) pathway…”
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