Search Results - "Agius, Thomas"
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Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Published in Nature communications (05-02-2024)“…Dietary restriction promotes resistance to surgical stress in multiple organisms. Counterintuitively, current medical protocols recommend short-term…”
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Acellular Perfusate is an Adequate Alternative to Packed Red Blood Cells During Normothermic Human Kidney Perfusion
Published in Transplantation direct (01-04-2024)“…Brief normothermic machine perfusion is increasingly used to assess and recondition grafts before transplant. During normothermic machine perfusion, metabolic…”
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Sodium Hydrosulfide Treatment During Porcine Kidney Ex Vivo Perfusion and Transplantation
Published in Transplantation direct (01-11-2023)“…Background. In rodents, hydrogen sulfide (H 2 S) reduces ischemia-reperfusion injury and improves renal graft function after transplantation. Here, we…”
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Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using 31P Magnetic Resonance Spectroscopic Imaging
Published in Transplantation direct (01-10-2022)“…Background. The ideal preservation temperature for donation after circulatory death kidney grafts is unknown. We investigated whether subnormothermic (22 °C)…”
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Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization
Published in JVS-vascular science (01-01-2023)“…Hydrogen sulfide is a proangiogenic gas produced primarily by the transsulfuration enzyme cystathionine-γ-lyase (CGL). CGL-dependent hydrogen sulfide…”
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In vivo magnetic resonance 31 P-Spectral Analysis With Neural Networks: 31P-SPAWNN
Published in Magnetic resonance in medicine (01-01-2023)“…We have introduced an artificial intelligence framework, 31P-SPAWNN, in order to fully analyze phosphorus-31 ( P) magnetic resonance spectra. The flexibility…”
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In vivo magnetic resonance 31P‐Spectral Analysis With Neural Networks: 31P‐SPAWNN
Published in Magnetic resonance in medicine (01-01-2023)“…Purpose We have introduced an artificial intelligence framework, 31P‐SPAWNN, in order to fully analyze phosphorus‐31 (31$$ {}^{31} $$P) magnetic resonance…”
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Ex Vivo Analysis of Kidney Graft Viability Using 31P Magnetic Resonance Imaging Spectroscopy
Published in Transplantation (01-09-2020)“…BACKGROUND.The lack of organs for kidney transplantation is a growing concern. Expansion in organ supply has been proposed through the use of organs after…”
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Two‐day Static Cold Preservation of α1,3‐Galactosyltransferase Knockout Kidney Grafts Before Simulated Xenotransplantation
Published in Xenotransplantation (Københaven) (01-07-2024)“…ABSTRACT Transplantation remains the preferred treatment for end‐stage kidney disease but is critically limited by the number of available organs. Xenografts…”
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Modified Tail Vein and Penile Vein Puncture for Blood Sampling in the Rat Model
Published in Journal of visualized experiments (30-06-2023)“…Blood samples are required in most experimental animal designs to assess various hematological parameters. This paper presents two procedures for blood…”
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Dietary or pharmacological inhibition of insulin-like growth factor-1 protects from renal ischemia-reperfusion injury in mice
Published in iScience (20-12-2024)“…One-week protein restriction (PR) limits ischemia-reperfusion (IR) damages and improves metabolic fitness. Similarly, longer-term calory restriction results in…”
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Role of post-transplant graft scintigraphy in kidney donation after circulatory death
Published in Frontiers in transplantation (19-12-2022)“…There is no consensus on how to predict post-transplant function of donation after circulatory death ( ) kidneys. Thus, we aimed to identify renal scintigraphy…”
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National Health Service
Published in British Medical Journal (21-02-1948)Get full text
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