Search Results - "Agirre, E."

Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition by Agirre, E., Oldfield, A. J., Bellora, N., Segelle, A., Luco, R. F.

“…Alternative splicing relies on the combinatorial recruitment of splicing regulators to specific RNA binding sites. Chromatin has been shown to impact this…”
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Word n-gram attention models for sentence similarity and inference by Lopez-Gazpio, I., Maritxalar, M., Lapata, M., Agirre, E.

“…•Bag-of-Words models boost their performance when making use of context.•Context in the form of arbitrary n-grams outperforms informed baselines.•Trainable…”
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Interpretable semantic textual similarity: Finding and explaining differences between sentences by Lopez-Gazpio, I., Maritxalar, M., Gonzalez-Agirre, A., Rigau, G., Uria, L., Agirre, E.

“…•We address interpretability, the ability of machines to explain their reasoning.•We formalize it for textual similarity as graded typed alignment between 2…”
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PhrasIS: Phrase Inference and Similarity benchmark by Lopez-Gazpio, I, Gaviria, J, García, P, Sanjurjo-González, H, Sanz, B, Zarranz, A, Maritxalar, M, Agirre, E

“…Abstract We present PhrasIS, a benchmark dataset composed of natural occurring Phrase pairs with Inference and Similarity annotations for the evaluation of…”
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Study of the influence of different variables on membrane fouling in submerged membrane bioreactors by Urkiaga, A., Iturbe, D., Etxebarria, J., Agirre, E.

“…Membrane fouling is still the greatest handicap to overcome in membrane bioreactor (MBR) technology. In this study, a multi-factorial experimental design was…”
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Chromatin and alternative splicing by Alló, M, Schor, I E, Muñoz, M J, de la Mata, M, Agirre, E, Valcárcel, J, Eyras, E, Kornblihtt, A R

“…Alternative splicing affects more than 90% of human genes. Coupling between transcription and splicing has become crucial in the complex network underlying…”
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On the Use of Automatically Acquired Examples for All-Nouns Word Sense Disambiguation by Martinez, D., Lopez de Lacalle, O., Agirre, E.

“…This article focuses on Word Sense Disambiguation (WSD), which is a Natural Language Processing task that is thought to be important for many Language…”
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Is the MNA an indicator of functional recovery in patients with hip fracture? by Artaza, I, Fernandez, N, Urkiza, M, Garcia, I, Uriarte, I, Agirre, E

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Regression and multilayer perceptron-based models to forecast hourly O3 and NO2 levels in the Bilbao area by Agirre-Basurko, E., Ibarra-Berastegi, G., Madariaga, I.

“…In this paper, we present the results obtained using three prognostic models to forecast ozone (O3) and nitrogen dioxide (NO2) levels in real-time up to 8h…”
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An Atlas of Vagal Sensory Neurons and Their Molecular Specialization by Kupari, Jussi, Häring, Martin, Agirre, Eneritz, Castelo-Branco, Gonçalo, Ernfors, Patrik

“…Sensory functions of the vagus nerve are critical for conscious perceptions and for monitoring visceral functions in the cardio-pulmonary and gastrointestinal…”
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Altered human oligodendrocyte heterogeneity in multiple sclerosis by Jäkel, Sarah, Agirre, Eneritz, Mendanha Falcão, Ana, van Bruggen, David, Lee, Ka Wai, Knuesel, Irene, Malhotra, Dheeraj, ffrench-Constant, Charles, Williams, Anna, Castelo-Branco, Gonçalo

“…Oligodendrocyte pathology is increasingly implicated in neurodegenerative diseases as oligodendrocytes both myelinate and provide metabolic support to axons…”
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Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation by Marisca, Roberta, Hoche, Tobias, Agirre, Eneritz, Hoodless, Laura Jane, Barkey, Wenke, Auer, Franziska, Castelo-Branco, Gonçalo, Czopka, Tim

“…Recent reports have revealed that oligodendrocyte precursor cells (OPCs) are heterogeneous. It remains unclear whether such heterogeneity reflects different…”
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Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis by Falcão, Ana Mendanha, van Bruggen, David, Marques, Sueli, Meijer, Mandy, Jäkel, Sarah, Agirre, Eneritz, Samudyata, Floriddia, Elisa M., Vanichkina, Darya P., ffrench-Constant, Charles, Williams, Anna, Guerreiro-Cacais, André Ortlieb, Castelo-Branco, Gonçalo

“…Multiple sclerosis (MS) is characterized by an immune system attack targeting myelin, which is produced by oligodendrocytes (OLs). We performed single-cell…”
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A lncRNA regulates alternative splicing via establishment of a splicing-specific chromatin signature by Gonzalez, Inma, Munita, Roberto, Agirre, Eneritz, Dittmer, Travis A, Gysling, Katia, Misteli, Tom, Luco, Reini F

“…The evolutionarily conserved antisense long noncoding RNA asFGFR2 influences cell type–specific alternative-splicing patterns of FGFR2 by recruiting chromatin…”
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A reproducible survey on word embeddings and ontology-based methods for word similarity: Linear combinations outperform the state of the art by Lastra-Díaz, Juan J., Goikoetxea, Josu, Hadj Taieb, Mohamed Ali, García-Serrano, Ana, Ben Aouicha, Mohamed, Agirre, Eneko

“…Human similarity and relatedness judgements between concepts underlie most of cognitive capabilities, such as categorisation, memory, decision-making and…”
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Spatial epigenome–transcriptome co-profiling of mammalian tissues by Zhang, Di, Deng, Yanxiang, Kukanja, Petra, Agirre, Eneritz, Bartosovic, Marek, Dong, Mingze, Ma, Cong, Ma, Sai, Su, Graham, Bao, Shuozhen, Liu, Yang, Xiao, Yang, Rosoklija, Gorazd B., Dwork, Andrew J., Mann, J. John, Leong, Kam W., Boldrini, Maura, Wang, Liya, Haeussler, Maximilian, Raphael, Benjamin J., Kluger, Yuval, Castelo-Branco, Gonçalo, Fan, Rong

“…Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics, are becoming powerful tools for profiling of cellular states in the…”
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Single-cell transcriptomic analysis of oligodendrocyte lineage cells by van Bruggen, David, Agirre, Eneritz, Castelo-Branco, Gonçalo

“…•Several studies catalogued central nervous system cell types by bulk and single-cell RNA-seq.•An unexpected heterogeneity of oligodendrocyte lineage cells is…”
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Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility by Meijer, Mandy, Agirre, Eneritz, Kabbe, Mukund, van Tuijn, Cassandra A., Heskol, Abeer, Zheng, Chao, Mendanha Falcão, Ana, Bartosovic, Marek, Kirby, Leslie, Calini, Daniela, Johnson, Michael R., Corces, M. Ryan, Montine, Thomas J., Chen, Xingqi, Chang, Howard Y., Malhotra, Dheeraj, Castelo-Branco, Gonçalo

“…Multiple sclerosis (MS) is characterized by a targeted attack on oligodendroglia (OLG) and myelin by immune cells, which are thought to be the main drivers of…”
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Mbp translocates to the nucleus in oligodendroglia to interact with DNA by Carlstrom, K, Kabbe, M, Agirre, E, Castelo-Branco, G

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A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development by Sahu, Sanjeeb Kumar, Agirre, Eneritz, Inayatullah, Mohammed, Mahesh, Arun, Tiwari, Neha, Lavin, Deborah P., Singh, Aditi, Strand, Susanne, Diken, Mustafa, Luco, Reini F., Belmonte, Juan Carlos Izpisua, Tiwari, Vijay K.

“…Epithelial-to-mesenchymal transition (EMT) renders epithelial cells migratory properties. While epigenetic and splicing changes have been implicated in EMT,…”
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