Search Results - "Agiannitopoulos, Konstantinos"

Analysis of hereditary cancer syndromes by using a panel of genes: novel and multiple pathogenic mutations by Tsaousis, Georgios N, Papadopoulou, Eirini, Apessos, Angela, Agiannitopoulos, Konstantinos, Pepe, Georgia, Kampouri, Stavroula, Diamantopoulos, Nikolaos, Floros, Theofanis, Iosifidou, Rodoniki, Katopodi, Ourania, Koumarianou, Anna, Markopoulos, Christos, Papazisis, Konstantinos, Venizelos, Vasileios, Xanthakis, Ioannis, Xepapadakis, Grigorios, Banu, Eugeniu, Eniu, Dan Tudor, Negru, Serban, Stanculeanu, Dana Lucia, Ungureanu, Andrei, Ozmen, Vahit, Tansan, Sualp, Tekinel, Mehmet, Yalcin, Suayib, Nasioulas, George

“…Hereditary cancer predisposition syndromes are responsible for approximately 5-10% of all diagnosed cancer cases. In the past, single-gene analysis of specific…”
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miRNA polymorphisms and risk of premature coronary artery disease by Agiannitopoulos, Konstantinos, Samara, Pinelopi, Papadopoulou, Miranta, Efthymiadou, Astradeni, Papadopoulou, Eirini, Tsaousis, Georgios N., Mertzanos, George, Babalis, Dimitrios, Lamnissou, Klea

“…Several microRNA (miRNA) polymorphisms have been associated with susceptibility to specific health disorders, including cardiovascular diseases. The aim of the…”
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Characterization of the c.793-1G > A splicing variant in CHEK2 gene as pathogenic: a case report by Agiannitopoulos, Konstantinos, Papadopoulou, Eirini, Tsaousis, Georgios N, Pepe, Georgia, Kampouri, Stavroula, Kocdor, Mehmet Ali, Nasioulas, George

“…CHEK2 is involved in the DNA damage repair response Fanconi anemia (FA)-BRCA pathway. An increased risk for breast and other cancers has been documented in…”
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Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation by Tsoulos, Nikolaos, Papadopoulou, Eirini, Agiannitopoulos, Konstantinos, Grigoriadis, Dimitrios, Tsaousis, Georgios N, Bouzarelou, Dimitra, Gogas, Helen, Troupis, Theodore, Venizelos, Vassileios, Fountzilas, Elena, Theochari, Maria, Ziogas, Dimitrios C, Giassas, Stylianos, Koumarianou, Anna, Christopoulou, Athina, Busby, George, Nasioulas, George, Markopoulos, Christos

“…Breast cancer (BC) is the most prominent tumor type among women, accounting for 32% of newly diagnosed cancer cases. BC risk factors include inherited germline…”
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Report of a germline double heterozygote in MSH2 and PALB2 by Agiannitopoulos, Konstantinos, Papadopoulou, Eirini, Tsaousis, Georgios N., Pepe, Georgia, Kampouri, Stavroula, Patsea, Eleni, Lypas, George, Nasioulas, George

“…Background Carriers with pathogenic variants in MSH2 have increased risk to develop colorectal, endometrium, ovarian, and other types of cancer. The PALB2 is…”
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Determination of EGFR and KRAS mutational status in Greek non-small-cell lung cancer patients by PAPADOPOULOU, EIRINI, TSOULOS, NIKOLAOS, TSIRIGOTI, ANGELIKI, APESSOS, ANGELA, AGIANNITOPOULOS, KONSTANTINOS, METAXA-MARIATOU, VASILIKI, ZAROGOULIDIS, KONSTANTINOS, ZAROGOULIDIS, PAVLOS, KASARAKIS, DIMITRIOS, KAKOLYRIS, STYLIANOS, DAHABREH, JUBRAIL, VLASTOS, FOTIS, ZOUBLIOS, CHARALAMPOS, RAPTI, AGGELIKI, PAPAGEORGIOU, NIKI GEORGATOU, VELDEKIS, DIMITRIOS, GAGA, MINA, ARAVANTINOS, GERASIMOS, KARAVASILIS, VASILEIOS, KARAGIANNIDIS, NAPOLEON, NASIOULAS, GEORGE

“…It has been reported that certain patients with non-small-cell lung cancer (NSCLC) that harbor activating somatic mutations within the tyrosine kinase domain…”
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Molecular predictive markers in tumors of the gastrointestinal tract by Papadopoulou, Eirini, Metaxa-Mariatou, Vasiliki, Tsaousis, Georgios, Tsoulos, Nikolaos, Tsirigoti, Angeliki, Efstathiadou, Chrisoula, Apessos, Angela, Agiannitopoulos, Konstantinos, Pepe, Georgia, Bourkoula, Eugenia, Nasioulas, George

“…Gastrointestinal malignancies are among the leading causes of cancer-related deaths worldwide. Like all human malignancies they are characterized by…”
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Neuroendocrine Breast Tumors: Could Multigene Assays Help in Guiding Treatment Decisions? Case Presentation by Markopoulos, Christos, Tsoulos, Nikolaos, Agiannitopoulos, Konstantinos, Karagianni, Evangelia

“…Breast cancer remains the most prevalent type of cancer among women worldwide, and it remains the primary cause of cancer-related deaths in this demographic…”
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CLINICAL CHARACTERIZATION AND MUTATION SPECTRUM IN CRETAN PATIENTS WITH HEREDITARY POLYPOSIS SYNDROMES by Velegraki, Magdalini, Fostira, Florentia, Saloustros, Emmanouil, Strehle, Andreas, Agiannitopoulos, Konstantinos, Mavroudis, Dimitrios, Paspatis, Grigorios

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Clinical and Molecular Genetic Analysis of Cases with Ectodermal Dysplasia by Yapijakis, Christos, Douka, Anna, Gintoni, Iphigenia, Agiannitopoulos, Konstantinos, Vlachakis, Dimitrios, Chrousos, George P

“…Ectodermal dysplasias are a group of >200 clinically and congenitally heterogeneous disorders characterized by abnormal development in the ectodermal…”
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Reclassification of Splicing Gene Variants in Hereditary Cancer: Cases Report and Literature Review by Bouzarelou, Dimitra, Agiannitopoulos, Konstantinos, Tsaousis, Georgios N, Papadopoulou, Eirini, Nasioulas, George

“…Alternative splicing (AS), a crucial cellular process, is a source of transcriptomic expansion and protein variability. Its contribution to cancer development…”
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A novel deletion of exon 4 in the Ectodysplasin A gene associated with X-linked hypohidrotic ectodermal dysplasia by Agiannitopoulos, Konstantinos, Potska, Kevisa, Douka, Anna, Gintoni, Iphigenia, Tsaousis, Georgios N., Papadopoulou, Eirini, Nasioulas, George, Yapijakis, Christos

“…Identify the disease-causing mutation in a patient with features of X-linked hypohidrotic ectodermal dysplasia, which is a genetic disorder characterized by…”
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Abstract P5-12-07: Polygenic Risk Score in a cohort of 105 Breast Cancer patients previously tested with a multi gene panel for hereditary cancer by Tsoulos, Nikolaos, Agiannitopoulos, Konstantinos, Goga, Helen, Troupis, Theodoros, Markopoulos, Christos

“…Abstract AIM: Most patients tested by a 44-gene panel for hereditary cancer (HerediGene), even though they had a strong family history, have a negative result…”
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Genetic testing in patients with pancreatic cancer to reveal pathogenic variants in cancer susceptibility genes by Tsoulos, Nikolaos, Potska, Kevisa, Agiannitopoulos, Konstantinos, Tsaousis, Georgios, Ozdogan, Mustafa, Karabulut, Bulent, Croitoru, Adina-Emilia, Ziogas, Dimitrios C., Theochari, Maria, Christodoulou, Christos, Samantas, Epaminondas, Janinis, Dimitrios, Athanasiadis, Ilias, Koutras, Angelos, Papadopoulou, Eirini, Nasioulas, George

“…e16276 Background: Pancreatic cancer is one of the most fatal malignancies. It accounts for 2% of all cancers and 5% of cancer-related deaths. Hence, it is…”
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Expression of miR-208b and miR-499 in Greek Patients with Acute Myocardial Infarction by Agiannitopoulos, Konstantinos, Pavlopoulou, Panagiota, Tsamis, Konstantinos, Bampali, Konstantina, Samara, Pinelopi, Nasioulas, George, Mertzanos, George, Babalis, Dimitrios, Lamnissou, Klea

“…Certain microRNAs (miRs) present in human plasma are candidate biomarkers for cardiovascular diseases, including acute myocardial infarction (AMI). We examined…”
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Germline Co-deletion of CDKN2A and CDKN2B Genes in Pleomorphic Xanthoastrocytoma: Case Report by Agiannitopoulos, Konstantinos, Katseli, Anastasia, Potska, Kevisa, Ntogka, Christina, Tsaousis, Georgios N, Tsoulos, Nikolaos, Kampoli, Katerina, Ntavatzikos, Anastasios, Papadopoulou, Eirini, Nasioulas, George, Koumarianou, Anna

“…Gliomas are highly heterogeneous malignancies originating from diverse cell types within the brain. Although their precise etiology is frequently unknown, risk…”
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Study on the admission levels of circulating cell-free DNA in patients with acute myocardial infarction using different quantification methods by Agiannitopoulos, Konstantinos, Samara, Pinelopi, Papadopoulou, Eirini, Tsamis, Konstantinos, Mertzanos, George, Babalis, Dimitrios, Lamnissou, Klea

“…Circulating cell-free DNA (cf-DNA) is present in human biological fluids, mainly in plasma and serum, originating from cell death, a process that massively…”
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Abstract P2-09-10: Different CNVs account for 10.4% of pathogenic variants in 1418 patients referred for hereditary breast cancer testing by Tsoulos, Nikolaos, Agiannitopoulos, Konstantinos, Pepe, Georgia, Papadopoulou, Eirini, Tsaousis, Georgios N, Apostolopoulou, Despina, Meintani, Angeliki, Venizelos, Vassileios, Markopoulos, Christos, Iosifidou, Rodoniki, Karageorgopoulou, Sofia, Christodoulou, Christos, Natsiopoulos, Ioannis, Papazisis, Konstantinos, Vasilaki-Antonatou, Maria, Kabletsas, Eleftherios, Psyrri, Amanta, Giassas, Stylianos, Ziogas, Dimitrios, Lalla, Efthalia, Koumarianou, Anna, Papadimitriou, Christos, Ozmen, Vahit, Tansan, Sualp, Kaban, Kerim, Ozatlı, Tahsin, Eniu, Dan Tudor, Chiorean, Angelica, Blidaru, Alexandru, Nasioulas, George

“…Abstract Background: Breast cancer is the most frequently diagnosed cancer in women and about 10% of breast cancer cases are hereditary. BRCA1 and BRCA2 are…”
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Evidence for association of the rs605059 polymorphism of HSD17B1 gene with recurrent spontaneous abortions by Ntostis, Panagiotis, Agiannitopoulos, Konstantinos, Tsaousis, Georgios, Pantos, Konstantinos, Lamnissou, Klea

“…Objective: To investigate whether the missense rs605059 polymorphism of HSD17B1 gene, which is expressed mainly in the placenta, is associated with recurrent…”
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Copy Number Variations (CNVs) Account for 10.8% of Pathogenic Variants in Patients Referred for Hereditary Cancer Testing by AGIANNITOPOULOS, KONSTANTINOS, PEPE, GEORGIA, TSAOUSIS, GEORGIOS N., POTSKA, KEVISA, BOUZARELOU, DIMITRA, KATSELI, ANASTASIA, NTOGKA, CHRISTINA, MEINTANI, ANGELIKI, TSOULOS, NIKOLAOS, GIASSAS, STYLIANOS, VENIZELOS, VASSILEIOS, MARKOPOULOS, CHRISTOS, IOSIFIDOU, RODONIKI, KARAGEORGOPOULOU, SOFIA, CHRISTODOULOU, CHRISTOS, NATSIOPOULOS, IOANNIS, PAPAZISIS, KONSTANTINOS, VASILAKI-ANTONATOU, MARIA, KABLETSAS, ELEFTHERIOS, PSYRRI, AMANTA, ZIOGAS, DIMITRIOS, LALLA, EFTHALIA, KOUMARIANOU, ANNA, ANASTASAKOU, KORNILIA, PAPADIMITRIOU, CHRISTOS, OZMEN, VAHIT, TANSAN, SUALP, KABAN, KERIM, OZATLI, TAHSIN, ENIU, DAN TUDOR, CHIOREAN, ANGELICA, BLIDARU, ALEXANDRU, RINSMA, MARRIT, PAPADOPOULOU, EIRINI, NASIOULAS, GEORGE

“…Background/Aim: Germline copy number variation (CNV) is a type of genetic variant that predisposes significantly to inherited cancers. Today, next-generation…”
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