Search Results - "Agianian, B"
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Synthesis of folate- pegylated polyester nanoparticles encapsulating ixabepilone for targeting folate receptor overexpressing breast cancer cells
Published in Journal of materials science. Materials in medicine (01-12-2015)“…The aim of this study was the preparation of novel polyester nanoparticles based on folic acid (FA)–functionalized poly(ethylene glycol)–poly(propylene…”
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Folate and Pegylated Aliphatic Polyester Nanoparticles for Targeted Anticancer Drug Delivery
Published in International journal of nanomedicine (01-01-2020)“…The use of chemotherapeutic agents to combat cancer is accompanied by high toxicity due to their inability to discriminate between cancer and normal cells…”
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Crystallization and preliminary X-ray analysis of Drosophila glutathione S-transferase-2
Published in Acta crystallographica. Section D, Biological crystallography. (01-05-2001)“…The σ‐class glutathione S‐transferase‐2 (GST‐2) from Drosophila melanogaster is predominantly found within the indirect flight muscles (IFMs), where it is…”
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Structure of a Drosophila Sigma Class Glutathione S-transferase Reveals a Novel Active Site Topography Suited for Lipid Peroxidation Products
Published in Journal of molecular biology (07-02-2003)“…Insect glutathione- S-transferases (GSTs) are grouped in three classes, I, II and recently III; class I (Delta class) enzymes together with class III members…”
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A troponin switch that regulates muscle contraction by stretch instead of calcium
Published in The EMBO journal (25-02-2004)“…The flight muscles of many insects have a form of regulation enabling them to contract at high frequencies. The muscles are activated by periodic stretches at…”
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p-Nitrophenyl α-d-Mannopyranoside Ethanol Solvate
Published in Acta crystallographica. Section C, Crystal structure communications (15-06-1997)Get full text
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Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14
Published in The Journal of biological chemistry (26-02-1999)“…Import of matrix proteins into peroxisomes requires two targeting signal-specific import receptors, Pex5p and Pex7p, and their binding partners at the…”
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The Regulation of Myosin Binding to Actin Filaments by Lethocerus Troponin
Published in Journal of molecular biology (26-10-2007)“…Lethocerus indirect flight muscle has two isoforms of troponin C, TnC-F1 and F2, which are unusual in having only a single C-terminal calcium binding site…”
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ATP increases the affinity between MutS ATPase domains. Implications for ATP hydrolysis and conformational changes
Published in The Journal of biological chemistry (15-10-2004)“…MutS is the key protein of the Escherichia coli DNA mismatch repair system. It recognizes mispaired and unpaired bases and has intrinsic ATPase activity. ATP…”
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Structure of apo-phosphatidylinositol transfer protein α provides insight into membrane association
Published in The EMBO journal (01-05-2002)“…Phosphatidylinositol transfer protein α (PITPα) is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of…”
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Troponin C in different insect muscle types: identification of two isoforms in Lethocerus, Drosophila and Anopheles that are specific to asynchronous flight muscle in the adult insect
Published in Biochemical journal (01-05-2003)“…The indirect flight muscles (IFMs) of Lethocerus (giant water bug) and Drosophila (fruitfly) are asynchronous: oscillatory contractions are produced by…”
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glutamine-rich domain of the Drosophila GAGA factor is necessary for amyloid fibre formation in vitro, but not for chromatin remodelling
Published in Journal of molecular biology (15-01-1999)“…The Drosophila GAGA factor binds specifically to the sequence GAGAG, and synergises with nucleosome remodelling factor to remodel chromatin in vitro. It…”
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Biophysical Characterization of the Influence of Salt on Tetrameric SecB
Published in Biophysical journal (01-07-2001)“…SecB is a tetrameric chaperone, with a monomeric molecular mass of 17 kDa, that is involved in protein translocation in Escherichia coli. It has been…”
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The Crystal Structure of the Complexes of Concanavalin A with 4′-Nitrophenyl-α-d-mannopyranoside and 4′-Nitrophenyl-α-d-glucopyranoside
Published in Journal of structural biology (01-05-1996)“…Concanavalin A (Con A) is the best-known plant lectin and has importantin vitrobiological activities arising from its specific saccharide-binding ability. Its…”
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A Triclinic Crystal Form of the Lectin Concanavalin A
Published in Journal of structural biology (01-07-1996)“…The molecular structure of a triclinic crystal form of concanavalin A has been refined at 2.4 Å resolution. The crystals have unit cell dimensionsa= 78.8 Å,b=…”
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