Search Results - "Aghdassi, A."

A structured weight loss program increases gut microbiota phylogenetic diversity and reduces levels of Collinsella in obese type 2 diabetics: A pilot study by Frost, Fabian, Storck, Lena J, Kacprowski, Tim, Gärtner, Simone, Rühlemann, Malte, Bang, Corinna, Franke, Andre, Völker, Uwe, Aghdassi, Ali A, Steveling, Antje, Mayerle, Julia, Weiss, Frank U, Homuth, Georg, Lerch, Markus M

“…The global obesity epidemic constitutes a major cause of morbidity and mortality challenging public health care systems worldwide. Thus, a better understanding…”
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Physical Activity, Energy Expenditure, Nutritional Habits, Quality of Sleep and Stress Levels in Shift-Working Health Care Personnel by Roskoden, Frederick Charles, Krüger, Janine, Vogt, Lena Johanna, Gärtner, Simone, Hannich, Hans Joachim, Steveling, Antje, Lerch, Markus M, Aghdassi, Ali A

“…Among health care personnel working regular hours or rotating shifts can affect parameters of general health and nutrition. We have investigated physical…”
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Examination of duodenal and colonic microbiome changes in mouse models of acute and chronic pancreatitis by Lange, Rabea, Glaubitz, Juliane, Frost, Fabian, Geisz, Andreas, Aghdassi, Ali A., Weiss, F. Ulrich, Sendler, Matthias

“…The exocrine pancreas is the main source of digestive enzymes which are released from secretory vesicles of acinar cells into the small intestine. Enzymes,…”
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Molecular Mechanism Contributing to Malnutrition and Sarcopenia in Patients with Liver Cirrhosis by Meyer, Fatuma, Bannert, Karen, Wiese, Mats, Esau, Susanne, Sautter, Lea F, Ehlers, Luise, Aghdassi, Ali A, Metges, Cornelia C, Garbe, Leif-A, Jaster, Robert, Lerch, Markus M, Lamprecht, Georg, Valentini, Luzia

“…Liver cirrhosis is frequently accompanied by disease-related malnutrition (DRM) and sarcopenia, defined as loss of skeletal muscle mass and function. DRM and…”
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In mouse chronic pancreatitis CD25+FOXP3+ regulatory T cells control pancreatic fibrosis by suppression of the type 2 immune response by Glaubitz, Juliane, Wilden, Anika, Golchert, Janine, Homuth, Georg, Völker, Uwe, Bröker, Barbara M., Thiele, Thomas, Lerch, Markus M., Mayerle, Julia, Aghdassi, Ali A., Weiss, Frank U., Sendler, Matthias

“…Chronic pancreatitis (CP) is characterized by chronic inflammation and the progressive fibrotic replacement of exocrine and endocrine pancreatic tissue. We…”
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Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis by Aghdassi, Ali A., John, Daniel S., Sendler, Matthias, Weiss, F. Ulrich, Reinheckel, Thomas, Mayerle, Julia, Lerch, Markus M.

“…Acute pancreatitis is a complex disorder involving both premature intracellular protease activation and inflammatory cell invasion. An initiating event is the…”
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Nutritional status in patients with chronic pancreatitis and liver cirrhosis is related to disease conditions and not dietary habits by Bruns, Niklas, Meyer, Fatuma, Rischmüller, Karen, Frost, Fabian, Tran, Quang Trung, Ittermann, Till, Bahls, Martin, Valentini, Luzia, Lamprecht, Georg, Lerch, Markus M., Aghdassi, Ali A., Wiese, Mats L.

“…Malnutrition is a common complication of chronic pancreatitis (CP) and liver cirrhosis (LC). Inadequate food intake is considered a relevant driver of…”
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Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin by John, Daniel S., Aschenbach, Julia, Krüger, Burkhard, Sendler, Matthias, Weiss, F. Ulrich, Mayerle, Julia, Lerch, Markus M., Aghdassi, Ali A.

“…Acute pancreatitis is characterized by premature intracellular protease activation and infiltration of inflammatory cells, mainly neutrophil granulocytes and…”
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Systemic Bile Acids Affect the Severity of Acute Pancreatitis in Mice Depending on Their Hydrophobicity and the Disease Pathogenesis by Tran, Quang Trung, Sendler, Matthias, Wiese, Mats L., Doller, Julia, Zierke, Lukas, Gischke, Marcel, Glaubitz, Juliane, Tran, Van Huy, Lalk, Michael, Bornscheuer, Uwe T., Weiss, Frank Ulrich, Lerch, Markus M., Aghdassi, Ali A.

“…Acute pancreatitis (AP) is a major, globally increasing gastrointestinal disease and a biliary origin is the most common cause. However, the effects of bile…”
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Carrying asymptomatic gallstones is not associated with changes in intestinal microbiota composition and diversity but cholecystectomy with significant dysbiosis by Frost, Fabian, Kacprowski, Tim, Rühlemann, Malte, Weiss, Stefan, Bang, Corinna, Franke, Andre, Pietzner, Maik, Aghdassi, Ali A., Sendler, Matthias, Völker, Uwe, Völzke, Henry, Mayerle, Julia, Weiss, Frank U., Homuth, Georg, Lerch, Markus M.

“…Gallstone disease affects up to twenty percent of the population in western countries and is a significant contributor to morbidity and health care…”
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Genetic Testing for Rare Diseases: A Systematic Review of Ethical Aspects by Kruse, Judith, Mueller, Regina, Aghdassi, Ali A, Lerch, Markus M, Salloch, Sabine

“…Genetic testing is associated with many ethical challenges on the individual, organizational and macro level of health care systems. The provision of genetic…”
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A GWAS meta‐analysis from 5 population‐based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome by Bonfiglio, F., Henström, M., Nag, A., Hadizadeh, F., Zheng, T., Cenit, M. C., Tigchelaar, E., Williams, F., Reznichenko, A., Ek, W. E., Rivera, N. V., Homuth, G., Aghdassi, A. A., Kacprowski, T., Männikkö, M., Karhunen, V., Bujanda, L., Rafter, J., Wijmenga, C., Ronkainen, J., Hysi, P., Zhernakova, A., D'Amato, M.

“…Background Irritable bowel syndrome (IBS) shows genetic predisposition, however, large‐scale, powered gene mapping studies are lacking. We sought to exploit…”
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Identification of early predictors for infected necrosis in acute pancreatitis by Wiese, Mats L, Urban, Steffi, von Rheinbaben, Sabrina, Frost, Fabian, Sendler, Matthias, Weiss, Frank Ulrich, Bülow, Robin, Kromrey, Marie-Luise, Tran, Quang Trung, Lerch, Markus M, Schauer, Birgit, Aghdassi, Ali A

“…Background In acute pancreatitis, secondary infection of pancreatic necrosis is a complication that mostly necessitates interventional therapy. A reliable…”
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Efficiency of a 15-Week Weight-Loss Program, Including a Low-Calorie Formula Diet, on Glycemic Control in Patients with Type 2 Diabetes Mellitus and Overweight or Obesity by Storck, Lena J., Meffert, Peter J., Rausch, Janine, Gärtner, Simone, Aghdassi, Ali A., Kühn, Jens-Peter, Kraft, Matthias, Pietzner, Maik, Lerch, Markus M., Steveling, Antje

“…Introduction: Patients who are overweight or obese have an increased risk of developing type 2 diabetes mellitus (T2DM). Weight loss can have a positive effect…”
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Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation by Frost, Fabian, Weiss, Stefan, Hertel, Johannes, Rühlemann, Malte, Bang, Corinna, Franke, Andre, Nauck, Matthias, Dörr, Marcus, Völzke, Henry, Roggenbuck, Dirk, Schierack, Peter, Völker, Uwe, Homuth, Georg, Aghdassi, Ali A, Sendler, Matthias, Lerch, Markus M, Weiss, Frank U

“…Antimicrobial autoantigenic glycoprotein 2 (GP2) is an important component of the innate immune system which originates from the exocrine pancreas as well as…”
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Magnetic Resonance Imaging of Changes in Abdominal Compartments in Obese Diabetics during a Low-Calorie Weight-Loss Program by Vogt, Lena J, Steveling, Antje, Meffert, Peter J, Kromrey, Marie-Luise, Kessler, Rebecca, Hosten, Norbert, Krüger, Janine, Gärtner, Simone, Aghdassi, Ali A, Mayerle, Julia, Lerch, Markus M, Kühn, Jens-Peter

“…To investigate changes in the fat content of abdominal compartments and muscle area during weight loss using confounder-adjusted chemical-shift-encoded…”
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An intensified trans-sectoral nutritional intervention in malnourished patients with chronic pancreatitis improves diseases prognosis and identifies potential biomarkers of nutritional status by Wiese, Mats L, Frost, Fabian, Meyer, Fatuma, Müller, Josefine, Valentini, Luzia, Rischmüller, Karen, Lamprecht, Georg, Steveling, Antje, Lerch, Markus M, Aghdassi, Ali A

“…Malnutrition is a common complication in chronic pancreatitis and associated with reduced quality of life and life expectancy. Nutritional support is…”
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Comparison of pancreatic size measurements in transabdominal ultrasound and magnetic resonance imaging and its dependence on age, gender, and body mass index in a population-based cohort by Aghdassi, A., Schauer, B., Duscha, D., Ittermann, T., Moskwa, P., Kromrey, M., Bülow, R., Völzke, H., Kühn, J., Lerch, M.

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Early Parenteral Nutrition in Patients with Biliopancreatic Mass Lesions, a Prospective, Randomized Intervention Trial by Krüger, Janine, Meffert, Peter J, Vogt, Lena J, Gärtner, Simone, Steveling, Antje, Kraft, Matthias, Mayerle, Julia, Lerch, Markus M, Aghdassi, Ali A

“…Patients with biliopancreatic tumors frequently suffer from weight loss and cachexia. The in-hospital work-up to differentiate between benign and malignant…”
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Animal models for investigating chronic pancreatitis by Aghdassi, Alexander A, Mayerle, Julia, Christochowitz, Sandra, Weiss, Frank U, Sendler, Matthias, Lerch, Markus M

“…Chronic pancreatitis is defined as a continuous or recurrent inflammatory disease of the pancreas characterized by progressive and irreversible morphological…”
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