Search Results - "Agha, Azza M"
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Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats
Published in European journal of pharmacology (05-10-2014)“…Pulmonary hypertension is a progressive disease of various origins that is associated with right ventricular dysfunction. In the present study, the protective…”
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2
Naringenin adds to the protective effect of l-arginine in monocrotaline-induced pulmonary hypertension in rats: Favorable modulation of oxidative stress, inflammation and nitric oxide
Published in European journal of pharmaceutical sciences (01-10-2014)“…[Display omitted] The present study was directed to investigate the possible modulatory effect of naringenin when co-administered with l-arginine in…”
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3
The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury
Published in Molecular neurobiology (01-02-2018)“…Adenosine impacts cerebral ischemia reperfusion (IR) through the inhibitory A 1 and the excitatory A 2 receptors. The present study aimed at investigating the…”
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4
Chloroquine ameliorates bone loss induced by d-galactose in male rats via inhibition of ERK associated osteoclastogenesis and antioxidant effect
Published in Toxicology reports (01-01-2021)“…[Display omitted] •Cloroquine (CQ) has reduced the adverse bone changes caused by d-galactose.•It improved bone health, switched off nuclear factor kappa-B…”
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5
Role of nitric oxide and KATP channel in the protective effect mediated by nicorandil in bile duct ligation-induced liver fibrosis in rats
Published in Biochemical pharmacology (01-05-2018)“…[Display omitted] Liver fibrosis is one of the most serious conditions affecting patients worldwide. In the present study, the role of nitric oxide and KATP…”
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6
Telmisartan: An angiotensin receptor blocker regulates osteoclastogenesis via inhibition of the ERK triggering in osteoporotic male rats
Published in Fundamental & clinical pharmacology (01-10-2022)“…Great attention was recently given to the importance of RAS in controlling inflammatory bone diseases, following the discovery of its local existence in…”
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17β-Estradiol augments antidepressant efficacy of escitalopram in ovariectomized rats: Neuroprotective and serotonin reuptake transporter modulatory effects
Published in Psychoneuroendocrinology (01-12-2016)“…Highlights • Estrogen augmented escitalopram’s effect in relieving menopausal depression. • Estrogen’s antidepressant effect was abolished by pretreatment with…”
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8
Pharmacological preconditioning with nicorandil and pioglitazone attenuates myocardial ischemia/reperfusion injury in rats
Published in European journal of pharmacology (01-08-2011)“…The present investigation was designed to study the cardioprotective effects of nicorandil and pioglitazone preconditioning in myocardial…”
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9
The Combination of α-Tocopheryl Succinate and Sodium Selenite on Breast Cancer: A Merit or a Demerit?
Published in Oxidative medicine and cellular longevity (01-01-2016)“…α-Tocopheryl succinate (α-TOS), a mitochondria-targeting agent, induces apoptosis in malignant cells in vitro and in vivo. Selenite is a nutritional supplement…”
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10
Potential protective effect of honey against paracetamol-induced hepatotoxicity
Published in Archives of Iranian medicine (01-11-2012)“…Paracetamol overdose causes severe hepatotoxicity that leads to liver failure in both humans and experimental animals. The present study investigates the…”
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11
Mechanisms Involved in the Anti-inflammatory and Vascular Effects of Iberis amara Extract
Published in Planta medica (01-08-2015)“…The anti-inflammatory potential and vasoprotective effects of an Iberis amara extract in a rat model of arthritis were investigated. I. amara, or bitter…”
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12
Red yeast rice and coenzyme Q10 as safe alternatives to surmount atorvastatin-induced myopathy in hyperlipidemic rats
Published in Canadian journal of physiology and pharmacology (01-06-2014)“…Statins are the first line treatment for the management of hyperlipidemia. However, the primary adverse effect limiting their use is myopathy. This study…”
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13
Comparative study of the cardioprotective effects of local and remote preconditioning in ischemia/reperfusion injury
Published in Life sciences (1973) (13-02-2012)“…Though the cardioprotective effects of local or remote preconditioning have been estimated, it is still unclear which of them is more reliable and provides…”
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14
Cardioprotective effects of ozone oxidative preconditioning in an in vivo model of ischemia/reperfusion injury in rats
Published in Scandinavian journal of clinical and laboratory investigation (01-09-2012)“…Abstract Background. Several studies have demonstrated the beneficial effects of ozone oxidative preconditioning in several pathologies characterized by…”
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15
Effects of Captopril on Interleukin-6, Leukotriene B4, and Oxidative Stress Markers in Serum and Inflammatory Exudate of Arthritic Rats: Evidence of Antiinflammatory Activity
Published in Toxicology and applied pharmacology (15-10-2000)“…We previously demonstrated that captopril (CP) exhibited a high ability to inhibit enzymatically generated leukotrienes, particularly LTB4, from stimulated…”
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16
Sildenafil inhibits agonist-evoked rat uterine contractility: influence of guanylyl cyclase inhibition
Published in European journal of pharmacology (12-10-2001)“…Sildenafil shows a potent relaxant effect on corpus cavernosum smooth muscles by prolonging cyclic guanosine monophosphate (cGMP) actions. We investigated…”
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17
Prophylactic Effect Of Aqueous Propolis Extract Against Acute Experimental Hepatotoxicity In Vivo
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-03-2002)“…Propolis has been extensively used in folk medicine for the management of a wide spectrum of disorders. In a previous study, we demonstrated the protective…”
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18
Central Adenosine A2A Receptor Blockade Modulates Reperfusion Injury Following Bilateral Carotid Occlusion
Published in The FASEB journal (01-04-2011)“…Prolonged oxygen and glucose deprivation to the brain of, if persistent, may eventually lead to neuronal death. In the present study, the effects of SCH 58261,…”
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The Combination of [alpha]-Tocopheryl Succinate and Sodium Selenite on Breast Cancer: A Merit or a Demerit?
Published in Oxidative medicine and cellular longevity (01-01-2016)“…α-Tocopheryl succinate (α-TOS), a mitochondria-targeting agent, induces apoptosis in malignant cells in vitro and in vivo. Selenite is a nutritional supplement…”
Get full text
Journal Article -
20
The Ying and Yang of Adenosine A 1 and A 2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury
Published in Molecular neurobiology (01-02-2018)“…Adenosine impacts cerebral ischemia reperfusion (IR) through the inhibitory A and the excitatory A receptors. The present study aimed at investigating the…”
Get full text
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