Search Results - "Aggleton, J. P."

Distinct subdivisions of the cingulum bundle revealed by diffusion MRI fibre tracking: Implications for neuropsychological investigations by Jones, D.K., Christiansen, K.F., Chapman, R.J., Aggleton, J.P.

“…The cingulum is a prominent white matter tract that supports prefrontal, parietal, and temporal lobe interactions. Despite being composed of both short and…”
Get full text

Uncovering a Role for the Dorsal Hippocampal Commissure in Recognition Memory by Postans, M, Parker, G D, Lundell, H, Ptito, M, Hamandi, K, Gray, W P, Aggleton, J P, Dyrby, T B, Jones, D K, Winter, M

“…Abstract The dorsal hippocampal commissure (DHC) is a white matter tract that provides interhemispheric connections between temporal lobe brain regions…”
Get full text

Mapping parahippocampal systems for recognition and recency memory in the absence of the rat hippocampus by Kinnavane, L., Amin, E., Horne, M., Aggleton, J. P.

“…The present study examined immediate‐early gene expression in the perirhinal cortex of rats with hippocampal lesions. The goal was to test those models of…”
Get full text

Magnitude of the Object Recognition Deficit Associated With Perirhinal Cortex Damage in Rats: Effects of Varying the Lesion Extent and the Duration of the Sample Period by Albasser, M. M, Davies, M, Futter, J. E, Aggleton, J. P

“…The present study examines 2 factors that might moderate the object-recognition deficit seen after perirhinal cortex damage. Object recognition by normal rats…”
Get full text

The rat retrosplenial cortex is required when visual cues are used flexibly to determine location by Hindley, E.L., Nelson, A.J.D., Aggleton, J.P., Vann, S.D.

“…•Combined loss of areas 29 and 30 impairs place discriminations.•Area 30 is needed for the control of place learning by visual cues.•Novel discrimination tasks…”
Get full text

Anterior thalamic nuclei lesions in rats disrupt markers of neural plasticity in distal limbic brain regions by Dumont, J.R, Amin, E, Poirier, G.L, Albasser, M.M, Aggleton, J.P

“…Highlights ► Anterior thalamic lesions alter the ratio of hippocampal CREB to pCREB. ► Anterior thalamic lesions reduced pCREB in granular retrosplenial…”
Get full text

The role of the hippocampus in mnemonic integration and retrieval: complementary evidence from lesion and inactivation studies by Iordanova, M. D., Burnett, D. J., Aggleton, J. P., Good, M., Honey, R. C.

“…Two forms of account have been proposed for how animals form integrated memories for patterns of stimulation: the elemental account holds that the elements…”
Get full text

An experimental test of the role of postsynaptic calcium levels in determining synaptic strength using perirhinal cortex of rat by Cho, K., Aggleton, J. P., Brown, M. W., Bashir, Z. I.

“…We have investigated the prediction of a relationship between the magnitude of activity-dependent increases in postsynaptic calcium and both the magnitude and…”
Get full text

Hippocampal inputs mediate theta-related plasticity in anterior thalamus by Tsanov, M, Wright, N, Vann, S.D, Erichsen, J.T, Aggleton, J.P, O'Mara, S.M

“…Abstract Hippocampally-driven oscillatory activity at theta frequency is found in the diencephalon, but an understanding of the fundamental role of theta in…”
Get full text

Effects of selective excitotoxic prefrontal lesions on acquisition of nonmatching- and matching-to-place in the T-maze in the rat: differential involvement of the prelimbic-infralimbic and anterior cingulate cortices in providing behavioural flexibility by Dias, R., Aggleton, J. P.

“…The present study investigated the contributions of the medial prefrontal cortex and its major subdivisions, the dorsal anterior cingulate (ACd) and…”
Get full text

Novel spatial arrangements of familiar visual stimuli promote activity in the rat hippocampal formation but not the parahippocampal cortices: a c- fos expression study by Jenkins, T.A, Amin, E, Pearce, J.M, Brown, M.W, Aggleton, J.P

“…The novelty of a cue may arise from the presence of an element that has not previously been experienced or from familiar elements that have been rearranged…”
Get full text

Differential cognitive effects of colloid cysts in the third ventricle that spare or compromise the fornix by Aggleton, J. P., McMackin, D., Carpenter, K., Hornak, J., Kapur, N., Halpin, S., Wiles, C. M., Kamel, H., Brennan, P., Carton, S., Gaffan, D.

“…A series of twelve cases, all of whom had received surgery for the removal of a colloid cyst in the third ventricle, was examined on a series of memory tests…”
Get full text

Post-surgical interval and lesion location within the limbic thalamus determine extent of retrosplenial cortex immediate-early gene hypoactivity by Poirier, G.L, Aggleton, J.P

“…Abstract Four experiments examined the disruptive effects of selective lesions in limbic thalamic nuclei on retrosplenial cortex function, as characterized by…”
Get full text

Early-onset dysfunction of retrosplenial cortex precedes overt amyloid plaque formation in Tg2576 mice by Poirier, G.L, Amin, E, Good, M.A, Aggleton, J.P

“…Abstract A mouse model of amyloid pathology was used to first examine using a cross sectional design changes in retrosplenial cortex activity in transgenic…”
Get full text

Extending the spontaneous preference test of recognition: evidence of object-location and object-context recognition by Dix, Sophie L., Aggleton, John P.

“…The natural preference for novel objects which is displayed by rats has been used as a behavioural index to test object recognition. In this series of…”
Get full text

A comparison of egocentric and allocentric spatial memory in a patient with selective hippocampal damage by Holdstock, J.S, Mayes, A.R, Cezayirli, E, Isaac, C.L, Aggleton, J.P, Roberts, N

“…The spatial memory of a single patient (YR) was investigated. This patient, who had relatively selective bilateral hippocampal damage, showed the pattern of…”
Get full text

The effects of hippocampal system lesions on a novel temporal discrimination task for rats by Kyd, R.J., Pearce, J.M., Haselgrove, M., Amin, E., Aggleton, J.P.

“…A novel, appetitive, Pavlovian conditioning task was used to assess interval timing. Experiment 1 showed that normal rats could discriminate between tones of…”
Get full text

Selective lamina dysregulation in granular retrosplenial cortex (area 29) after anterior thalamic lesions: an in situ hybridization and trans-neuronal tracing study in rats by Amin, E, Wright, N, Poirier, G.L, Thomas, K.L, Erichsen, J.T, Aggleton, J.P

“…Abstract There is growing evidence that lesions of the anterior thalamic nuclei cause long-lasting intrinsic changes to retrosplenial cortex, with the…”
Get full text

The Frequency and Extent of Mammillary Body Atrophy Associated with Surgical Removal of a Colloid Cyst by Denby, C.E, Vann, S.D, Tsivilis, D, Aggleton, J.P, Montaldi, D, Roberts, N, Mayes, A.R

“…Patients who have had a colloid cyst removed from the third ventricle sometimes experience some difficulty with day-to-day memory. This study provided…”
Get full text

Benzodiazepine impairment of perirhinal cortical plasticity and recognition memory by Wan, H., Warburton, E. C., Zhu, X. O., Koder, T. J., Park, Y., Aggleton, J. P., Cho, K., Bashir, Z. I., Brown, M. W.

“…Benzodiazepines, including lorazepam, are widely used in human medicine as anxiolytics or sedatives, and at higher doses can produce amnesia. Here we…”
Get full text