Search Results - "Aggeler, J"

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane by Barcellos-Hoff, M H, Aggeler, J, Ram, T G, Bissell, M J

“…An essential feature of mammary gland differentiation during pregnancy is the formation of alveoli composed of polarized epithelial cells, which, under the…”
Get full text

Tools to Measure Cell Health and Cytotoxicity Using High Content Imaging and Analysis by Mandavilli, Bhaskar S, Aggeler, Robert J, Chambers, Kevin M

“…High content screening (HCS)-based multiparametric measurements are very useful in early toxicity testing and safety assessment during drug development, and…”
Get more information

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells by Li, M.L, Aggeler, J, Farson, D.A, Hatier, C, Hassell, J, Bissell, M.J

“…When primary mouse mammary epithelial cells are cultured on plastic, they rapidly lose their ability to synthesize and secrete most milk proteins even in the…”
Get full text

Initial Events during Phagocytosis by Macrophages Viewed from outside and inside the Cell: Membrane-Particle Interactions and Clathrin by Aggeler, Judith, Werb, Zena

“…The initial events during phagocytosis of latex beads by mouse peritoneal macrophages were visualized by high-resolution electron microscopy of platinum…”
Get full text

Commitment to Expression of the Metalloendopeptidases, Collagenase and Stromelysin: Relationship of Inducing Events to Changes in Cytoskeletal Architecture by Werb, Zena, Hembry, Rosalind M., Murphy, Gillian, Aggeler, Judith

“…Agents that alter the morphology of rabbit synovial fibroblasts induce synthesis of the metalloendopeptidases, collagenase and stromelysin. We studied the…”
Get full text

Changes in Cell Shape Correlate with Collagenase Gene Expression in Rabbit Synovial Fibroblasts by Aggeler, Judith, Frisch, Steven M., Werb, Zena

“…Induction of the neutral proteinase, collagenase, is a marker for a specific switch in gene expression observed in rabbit synovial fibroblasts. A variety of…”
Get full text

Dynamic reciprocity: how do extracellular matrix and hormones direct gene expression? by Bissell, M J, Aggeler, J

“…Using mouse mammary epithelial cells (MME) as a model, we show that extracellular matrix (ECM) plays a fundamental role in the maintenance of tissue-specific…”
Get more information

Collagenase Is a Major Gene Product of Induced Rabbit Synovial Fibroblasts by Aggeler, Judith, Frisch, Steven M., Werb, Zena

“…We have investigated the effects of the tumor-promoting phorbol diester, 12-O-tetradecanoylphorbol-13-acetate (TPA), on rabbit synovial fibroblasts, and found…”
Get full text

High-Resolution Three-Dimensional Views of Membrane-Associated Clathrin and Cytoskeleton in Critical-Point-Dried Macrophages by Aggeler, Judith, Takemura, Reiko, Werb, Zena

“…We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of…”
Get full text

Three-Dimensional Organization of the Extracellular Matrix Secreted by Cultured Rat Smooth Muscle Cells by Aggeler, Judith

“…Specific interactions between cells and the extracellular matrix (ECM) in which they are embedded play a vital role in tissue organization. In recent years,…”
Get full text

Proteases Induce Secretion of Collagenase and Plasminogen Activator by Fibroblasts by Werb, Zena, Aggeler, Judith

“…We have observed that treatment of rabbit synovial fibroblasts with proteolytic enzymes can induce secretion of collagenase (EC 3.4.24.7) and plasminogen…”
Get full text

Degradation of Extracellular Matrix by Mouse Trophoblast Outgrowths: A Model for Implantation by Glass, Robert H., Aggeler, Judith, Spindle, Akiko, Pedersen, Roger A., Werb, Zena

“…During implantation the embryo attaches to the endometrial surface and trophoblast traverses the uterine epithelium, anchoring in the uterine connective…”
Get full text

386 - Live Cell Analysis of Dynamic Changes in Glutathione Redox Potentials and Hydrogen Peroxide with Genetically Encoded Premo™ Sensors by Mandavilli, Bhaskar S, Aggeler, Robert J, Yan, Michelle, Hanson, George

Get full text

Live Cell Analysis of Dynamic Changes in Glutathione Redox Potentials and Hydrogen Peroxide with Genetically Encoded Premo™ Sensors by Mandavilli, Bhaskar S, Aggeler, Robert J, Yan, Michelle, Hanson, George

Get full text

Cytoskeletal dynamics in rabbit synovial fibroblasts: I. Effects of acrylamide on intermediate filaments and microfilaments by Aggeler, J, Seely, K

“…Rabbit synovial fibroblasts respond to changes in cell shape and cytoskeletal architecture by altering specific gene expression. We have tested the ability of…”
Get more information

Cell-Based Analysis of Oxidative Stress, Lipid Peroxidation and Lipid Peroxidation-Derived Protein Modifications using Fluorescence Microscopy by Mandavilli, Bhaskar S, Aggeler, Robert J, Singh, Upinder, Chol Kang, Hee, Gee, Kyle, Agnew, Brian, Janes, Michael S

Get full text

A model system for studying membrane biogenesis : overexpression of cytochrome b5 in yeast results in marked proliferation of the intracellular membrane by VERGERES, G, YEN, T. S. B, AGGELER, J, LAUSIER, J, WASKELL, L

“…Cytochrome b5 is an amphipathic microsomal protein that is anchored to the endoplasmic reticulum by a single hydrophobic transmembrane alpha-helix located near…”
Get full text

Structure, distribution and composition of the extracellular matrix of human oocytes and cumulus masses by Dandekar, P, Aggeler, J, Talbot, P

“…The structure, distribution and composition of the extracellular matrix present around the human oocyte and in the cumulus was examined following fixation in…”
Get more information

Cell-Based Analysis of Lipid Peroxidation and Lipid Peroxidation-Derived Protein Modifications Using Fluorescence Microscopy and High Content Imaging by Mandavilli, Bhaskar S., Aggeler, Robert J., Rukavishnikov, Aleksey, Pickens, Chad, Singh, Upinder, Kang, Hee Chol, Gee, Kyle, Agnew, Brian, Janes, Michael S.

Get full text

Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo by AGGELER, J, WARD, J, BLACKIE, L. M, BARCELLOS-HOFF, M. H, STREULI, C. H, BISSELL, M. J

“…In the present study we provide evidence that the cytodifferentiation of primary mouse mammary epithelial cells within the alveolar-like structures formed…”
Get full text