Search Results - "Aggarwal, Varinder K."

Metal-free photoinduced C(sp3)–H borylation of alkanes by Shu, Chao, Noble, Adam, Aggarwal, Varinder K.

“…Boronic acids and their derivatives are some of the most useful reagents in the chemical sciences 1 , with applications spanning pharmaceuticals, agrochemicals…”
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Lithiation–Borylation Methodology and Its Application in Synthesis by Leonori, Daniele, Aggarwal, Varinder K

“…Conspectus Developing new methods that enable the synthesis of new and complex molecules with complete control of their 3-D shape is central to the advancement…”
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Stereospecific Couplings of Secondary and Tertiary Boronic Esters by Leonori, Daniele, Aggarwal, Varinder K.

“…This Minireview highlights advances in the Suzuki–Miyaura cross‐coupling of secondary boron reagents for the creation of CC bonds with control of…”
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Photoredox‐Catalyzed Cyclobutane Synthesis by a Deboronative Radical Addition–Polar Cyclization Cascade by Shu, Chao, Noble, Adam, Aggarwal, Varinder K.

“…Photoredox‐catalyzed methylcyclobutanations of alkylboronic esters are described. The reactions proceed through single‐electron transfer induced deboronative…”
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Photoinduced decarboxylative borylation of carboxylic acids by Fawcett, Alexander, Pradeilles, Johan, Wang, Yahui, Mutsuga, Tatsuya, Myers, Eddie L., Aggarwal, Varinder K.

“…The conversion of widely available carboxylic acids into versatile boronic esters would be highly enabling for synthesis. We found that this transformation can…”
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Catalyst‐Free Deaminative Functionalizations of Primary Amines by Photoinduced Single‐Electron Transfer by Wu, Jingjing, Grant, Phillip S., Li, Xiabing, Noble, Adam, Aggarwal, Varinder K.

“…The use of pyridinium‐activated primary amines as photoactive functional groups for deaminative generation of alkyl radicals under catalyst‐free conditions is…”
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1,3‐Difunctionalizations of [1.1.1]Propellane via 1,2‐Metallate Rearrangements of Boronate Complexes by Yu, Songjie, Jing, Changcheng, Noble, Adam, Aggarwal, Varinder K.

“…1,3‐Disubstituted bicyclo[1.1.1]pentanes (BCPs) are valuable bioisosteres of para‐substituted aromatic rings. The most direct route to these structures is via…”
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Photoinduced Deoxygenative Borylations of Aliphatic Alcohols by Wu, Jingjing, Bär, Robin M., Guo, Lin, Noble, Adam, Aggarwal, Varinder K.

“…A photochemical method for converting aliphatic alcohols into boronic esters is described. Preactivation of the alcohol as a 2‐iodophenyl‐thionocarbonate…”
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Stereocontrolled Total Synthesis of (−)‐Stemaphylline by Varela, Ana, Garve, Lennart K. B., Leonori, Daniele, Aggarwal, Varinder K.

“…Homologation of readily available α‐boryl pyrrolidines with metal carbenoids is especially challenging even when good leaving groups (Cl−) are employed. By…”
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Synthesis of Functionalized Cyclopropanes from Carboxylic Acids by a Radical Addition–Polar Cyclization Cascade by Shu, Chao, Mega, Riccardo S., Andreassen, Björn J., Noble, Adam, Aggarwal, Varinder K.

“…Herein, we describe the development of a photoredox‐catalyzed decarboxylative radical addition–polar cyclization cascade approach to functionalized…”
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Strain-Release-Driven Homologation of Boronic Esters: Application to the Modular Synthesis of Azetidines by Fawcett, Alexander, Murtaza, Amna, Gregson, Charlotte H. U, Aggarwal, Varinder K

“…Azetidines are important motifs in medicinal chemistry, but there are a limited number of methods for their synthesis. Herein, we present a new method for…”
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Synthesis of hydroxyphthioceranic acid using a traceless lithiation–borylation–protodeboronation strategy by Rasappan, Ramesh, Aggarwal, Varinder K.

“…In planning organic syntheses, disconnections are most often made adjacent to functional groups, which assist in C–C bond formation. For molecules devoid of…”
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Asymmetric Synthesis of Secondary and Tertiary Boronic Esters by Collins, Beatrice S. L., Wilson, Claire M., Myers, Eddie L., Aggarwal, Varinder K.

“…Non‐racemic chiral boronic esters are recognised as immensely valuable building blocks in modern organic synthesis. Their stereospecific transformation into a…”
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Convergent Deboronative and Decarboxylative Phosphonylation Enabled by the Phosphite Radical Trap “BecaP” by Pagire, Santosh K., Shu, Chao, Reich, Dominik, Noble, Adam, Aggarwal, Varinder K.

“…Carbon–phosphorus bond formation is significant in synthetic chemistry because phosphorus-containing compounds offer numerous indispensable biochemical roles…”
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Toward Ideality: The Synthesis of (+)-Kalkitoxin and (+)-Hydroxyphthioceranic Acid by Assembly-Line Synthesis by Balieu, Sebastien, Hallett, Gayle E, Burns, Matthew, Bootwicha, Teerawut, Studley, John, Aggarwal, Varinder K

“…The iterative homologation of boronic esters using chiral lithiated benzoate esters and chloromethyllithium has been applied to the highly efficient syntheses…”
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Synthesis of Enantioenriched Alkylfluorides by the Fluorination of Boronate Complexes by Sandford, Christopher, Rasappan, Ramesh, Aggarwal, Varinder K

“…The enantiospecific conversion of chiral secondary boronic esters into alkylfluorides is reported. Boronate complexes derived from boronic esters and PhLi were…”
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Special Collection on Boron Chemistry by Aggarwal, Varinder K., Xie, Zuowei, Ito, Hajime

“…In this Guest Editorial, Varinder Aggarwal, Zuowei Xie and Hajime Ito introduce the joint EurJOC/AsianJOC special collection on boron chemistry, which features…”
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Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters by Fairchild, Molly E., Noble, Adam, Aggarwal, Varinder K.

“…The synthesis of molecules bearing two or more contiguous, quaternary stereocenters is challenging, owing to the difficulty in controlling stereochemistry…”
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Photoinduced Fragmentation Borylation of Cyclic Alcohols and Hemiacetals by Shu, Chao, Madhavachary, Rudrakshula, Noble, Adam, Aggarwal, Varinder K

“…A visible-light photoinduced fragmentation borylation of O-phthalimido cycloalkanols with bis­(catecholato)­diboron is described. Structurally diverse keto and…”
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Ring-Expansion Induced 1,2-Metalate Rearrangements: Highly Diastereoselective Synthesis of Cyclobutyl Boronic Esters by Hari, Durga Prasad, Abell, Joseph C, Fasano, Valerio, Aggarwal, Varinder K

“…The broad synthetic utility of organoboron compounds stems from their ready ability to undergo 1,2-migrations. Normally, such shifts are induced by α-leaving…”
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