Search Results - "Aggarwal, Neil"

Diverse macrophage populations mediate acute lung inflammation and resolution by Aggarwal, Neil R, King, Landon S, D'Alessio, Franco R

“…Acute respiratory distress syndrome (ARDS) is a devastating disease with distinct pathological stages. Fundamental to ARDS is the acute onset of lung…”
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Advancing President Biden’s Equity Agenda — Lessons from Disparities Work by Aggarwal, Neil K

“…On his first day in office, President Biden signed an executive order on advancing racial equity and supporting underserved communities. This policy presents…”
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Diversity and Inclusion Training in Health Care: What the Evidence Suggests by Aggarwal, Neil Krishan

“…On September 22, 2020, then-President Donald Trump signed Executive Order 13950, titled “Combating Race and Sex Stereotyping.” This order restricted the types…”
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Reporting Grantee Demographics for Diversity, Equity, and Inclusion in Neuroscience by Choudhury, Suparna, Aggarwal, Neil K

“…Professional neuroscience organizations have recently pledged their commitments to diversity, equity, and inclusion in examining institutional discrimination;…”
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Real-world use of nirmatrelvir–ritonavir in outpatients with COVID-19 during the era of omicron variants including BA.4 and BA.5 in Colorado, USA: a retrospective cohort study by Aggarwal, Neil R, Molina, Kyle C, Beaty, Laurel E, Bennett, Tellen D, Carlson, Nichole E, Mayer, David A, Peers, Jennifer L, Russell, Seth, Wynia, Matthew K, Ginde, Adit A

“…Nirmatrelvir is a protease inhibitor with in-vitro activity against SARS-CoV-2, and ritonavir-boosted nirmatrelvir can reduce the risk of progression to severe…”
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A New Era in Critical Care Trials: Linking ICU Practice to Long-Term Outcomes by Hippensteel, Joseph A, Aggarwal, Neil R, Mikkelsen, Mark E

“…A new era in critical care trials is emerging, focusing on the link between ICU practice and long-term outcomes. The COPILOT study, published in the American…”
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Acute Lung Injury Review by Tsushima, Kenji, King, Landon S., Aggarwal, Neil R., Gorordo, Antonio De, D'Alessio, Franco R., Kubo, Keishi

“…The first report of acute respiratory distress syndrome (ARDS) was published in 1967, and even now acute lung injury (ALI) and ARDS are severe forms of diffuse…”
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Oxygen Exposure Resulting in Arterial Oxygen Tensions Above the Protocol Goal Was Associated With Worse Clinical Outcomes in Acute Respiratory Distress Syndrome by Aggarwal, Neil R., Brower, Roy G., Hager, David N., Thompson, B. Taylor, Netzer, Giora, Shanholtz, Carl, Lagakos, Adrian, Checkley, William

“…OBJECTIVES:High fractions of inspired oxygen may augment lung damage to exacerbate lung injury in patients with acute respiratory distress syndrome…”
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HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation by Brune, Kieran A, Ferreira, Fernanda, Mandke, Pooja, Chau, Eric, Aggarwal, Neil R, D'Alessio, Franco R, Lambert, Allison A, Kirk, Gregory, Blankson, Joel, Drummond, M Bradley, Tsibris, Athe M, Sidhaye, Venkataramana K

“…Several clinical studies show that individuals with HIV are at an increased risk for worsened lung function and for the development of COPD, although the…”
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Real-World Evidence of the Neutralizing Monoclonal Antibody Sotrovimab for Preventing Hospitalization and Mortality in COVID-19 Outpatients by Aggarwal, Neil R, Beaty, Laurel E, Bennett, Tellen D, Carlson, Nichole E, Davis, Christopher B, Kwan, Bethany M, Mayer, David A, Ong, Toan C, Russell, Seth, Steele, Jeffrey, Wogu, Adane F, Wynia, Matthew K, Zane, Richard D, Ginde, Adit A

“…It is not known whether sotrovimab, a neutralizing monoclonal antibody (mAb) treatment authorized for early symptomatic coronavirus disease 2019 (COVID-19)…”
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CD4+CD25+Foxp3+ Tregs resolve experimental lung injury in mice and are present in humans with acute lung injury by D'Alessio, Franco R, Tsushima, Kenji, Aggarwal, Neil R, West, Erin E, Willett, Matthew H, Britos, Martin F, Pipeling, Matthew R, Brower, Roy G, Tuder, Rubin M, McDyer, John F, King, Landon S

“…Acute lung injury (ALI) is characterized by rapid alveolar injury, inflammation, cytokine induction, and neutrophil accumulation. Although early events in the…”
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Advancing precision medicine for acute respiratory distress syndrome by Beitler, Jeremy R, Thompson, B Taylor, Baron, Rebecca M, Bastarache, Julie A, Denlinger, Loren C, Esserman, Laura, Gong, Michelle N, LaVange, Lisa M, Lewis, Roger J, Marshall, John C, Martin, Thomas R, McAuley, Daniel F, Meyer, Nuala J, Moss, Marc, Reineck, Lora A, Rubin, Eileen, Schmidt, Eric P, Standiford, Theodore J, Ware, Lorraine B, Wong, Hector R, Aggarwal, Neil R, Calfee, Carolyn S

“…Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome. Understanding of the complex pathways involved in lung injury pathogenesis,…”
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Radicalization to Violence: A View from Cultural Psychiatry by Rousseau, Cécile, Aggarwal, Neil K., Kirmayer, Laurence J.

“…This article introduces a thematic issue of Transcultural Psychiatry with selected papers from the McGill Advanced Study Institute in Cultural Psychiatry on…”
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Flow-cytometric method for simultaneous analysis of mouse lung epithelial, endothelial, and hematopoietic lineage cells by Singer, Benjamin D, Mock, Jason R, D'Alessio, Franco R, Aggarwal, Neil R, Mandke, Pooja, Johnston, Laura, Damarla, Mahendra

“…Flow cytometry is a powerful tool capable of simultaneously analyzing multiple parameters on a cell-by-cell basis. Lung tissue preparation for flow cytometry…”
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Change in effectiveness of sotrovimab for preventing hospitalization and mortality for at-risk COVID-19 outpatients during an Omicron BA.1 and BA.1.1-predominant phase by Aggarwal, Neil R., Beaty, Laurel E., Bennett, Tellen D., Carlson, Nichole E., Mayer, David A., Molina, Kyle C., Peers, Jennifer L., Russell, Seth, Wynia, Matthew K., Ginde, Adit A.

“…•Adult outpatients infected with Omicron BA.1 or BA.1.1 were administered sotrovimab.•Sotrovimab did not reduce hospitalization compared to all untreated…”
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Opportunities for improved clinical trial designs in acute respiratory distress syndrome by Wick, Katherine D, Aggarwal, Neil R, Curley, Martha A Q, Fowler, Alpha A, Jaber, Samir, Kostrubiec, Maciej, Lassau, Nathalie, Laterre, Pierre François, Lebreton, Guillaume, Levitt, Joseph E, Mebazaa, Alexandre, Rubin, Eileen, Sinha, Pratik, Ware, Lorraine B, Matthay, Michael A

“…The acute respiratory distress syndrome (ARDS) is a common critical illness syndrome with high morbidity and mortality. There are no proven pharmacological…”
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Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment by Garibaldi, Brian T, D'Alessio, Franco R, Mock, Jason R, Files, D Clark, Chau, Eric, Eto, Yoshiki, Drummond, M Bradley, Aggarwal, Neil R, Sidhaye, Venkataramana, King, Landon S

“…Acute lung injury (ALI) causes significant morbidity and mortality. Fibroproliferation in ALI results in worse outcomes, but the mechanisms governing…”
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Culture, Psychology, and National Security Against War on Terror Detainees by Aggarwal, Neil K.

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Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines—Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials by Buchman, Timothy G., Draghia-Akli, Ruxandra, Adam, Stacey J., Aggarwal, Neil R., Fessel, Joshua P., Higgs, Elizabeth S., Menetski, Joseph P., Read, Sarah W., Hughes, Eric A.

“…Given the urgent need for coronavirus disease 2019 therapeutics, early in the pandemic the Accelerating Coronavirus Disease 2019 Therapeutic Interventions and…”
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Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation by Singer, Benjamin D, Mock, Jason R, Aggarwal, Neil R, Garibaldi, Brian T, Sidhaye, Venkataramana K, Florez, Marcus A, Chau, Eric, Gibbs, Kevin W, Mandke, Pooja, Tripathi, Ashutosh, Yegnasubramanian, Srinivasan, King, Landon S, D'Alessio, Franco R

“…Acute respiratory distress syndrome (ARDS) is a common and often fatal inflammatory lung condition without effective targeted therapies. Regulatory T cells…”
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