Search Results - "Ageedi, Waleed"

Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue by Li, Yanming, Ren, Pingping, Dawson, Ashley, Vasquez, Hernan G., Ageedi, Waleed, Zhang, Chen, Luo, Wei, Chen, Rui, Li, Yumei, Kim, Sangbae, Lu, Hong S., Cassis, Lisa A., Coselli, Joseph S., Daugherty, Alan, Shen, Ying H., LeMaire, Scott A.

“…Background: Ascending thoracic aortic aneurysm (ATAA) is caused by the progressive weakening and dilatation of the aortic wall and can lead to aortic…”
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AIM2 Inflammasome Activation Contributes to Aortic Dissection in a Sporadic Aortic Disease Mouse Model by Ageedi, Waleed, Zhang, Chen, Frankel, William Case, Dawson, Ashley, Li, Yang, Coselli, Joseph S., Shen, Hu Ying, LeMaire, Scott A.

“…•The AIM2 inflammasome signaling pathway was upregulated in human ascending thoracic aortic dissection and was associated with smooth muscle cell…”
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Abstract 15530: Single-cell Analysis in Aortic Aneurysmal Tissue From Patients With Marfan Syndrome Reveals Increased Tgf-beta Production but Downregulation of Downstream Canonical Tgf-beta Signaling Pathways by Dawson, Ashley, Li, Yanming, Ren, Pingping, Vasquez, Hernan, Zhang, Chen, Appel, Richard, Ageedi, Waleed, Luo, Wei, Zhang, Lin, Li, Yang, Sheppard, Mary B, Lu, Hong S, Cassis, Lisa A, Coselli, Joseph S, Daugherty, Alan, Shen, Ying H, Lemaire, Scott A

“…BackgroundMarfan syndrome (MFS) is caused by mutations in the gene for fibrillin-1 (FBN1); however, the mechanisms by which these mutations cause aortic…”
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Abstract 15539: Single-cell Analysis of Aortic Tissues From Patients With Marfan Syndrome Reveals Changes in Smooth Muscle Cell Differentiation by Dawson, Ashley, Li, Yanming, Ren, Pingping, Vasquez, Hernan, Zhang, Chen, Ageedi, Waleed, Luo, Wei, Zhang, Lin, Li, Yang, Sheppard, Mary B, Lu, Hong S, Cassis, Lisa A, Coselli, Joseph S, Daugherty, Alan, Shen, Ying H, Lemaire, Scott A

“…BackgroundThoracic aortic aneurysms associated with Marfan syndrome (MFS) carry a high risk of mortality; however, the molecular and cellular processes leading…”
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Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling by Dawson, Ashley, Li, Yanming, Li, Yang, Ren, Pingping, Vasquez, Hernan G, Zhang, Chen, Rebello, Kimberly R, Ageedi, Waleed, Azares, Alon R, Mattar, Aladdein Burchett, Sheppard, Mary Burchett, Lu, Hong S, Coselli, Joseph S, Cassis, Lisa A, Daugherty, Alan, Shen, Ying H, LeMaire, Scott A

“…The molecular and cellular processes leading to aortic aneurysm development in Marfan syndrome (MFS) remain poorly understood. In this study, we examined the…”
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