Search Results - "Agdeppa, E D"
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Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Naphthylethylidene Derivatives as Positron Emission Tomography Imaging Probes for beta -Amyloid Plaques in Alzheimer's Disease
Published in The Journal of neuroscience (15-12-2001)“…Senile plaques (SPs) and neurofibrillary tangles (NFTs) are hallmark pathologies accompanying the neurodegeneration involved in Alzheimer's disease (AD), for…”
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In vitro detection of ( S)-naproxen and ibuprofen binding to plaques in the Alzheimer’s brain using the positron emission tomography molecular imaging probe 2-(1-{6-[(2-[ 18F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile
Published in Neuroscience (01-03-2003)“…Epidemiological studies have suggested that the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the relative risk of Alzheimer’s disease…”
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In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile
Published in Neuroscience (2003)“…Epidemiological studies have suggested that the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the relative risk of Alzheimer's disease…”
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In vivo brain imaging of tangle burden in humans
Published in Journal of molecular neuroscience (01-12-2002)“…Cerebral neurofibrillary tangles (NFTs) accumulate in a predictable sequence decades before the clinical symptoms of Alzheimer's disease emerge, and the degree…”
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