Search Results - "Agbani, Ejaife O"

Low α-Thrombin/GPIbα Interaction Is a Potential Contributor to Platelet Hyper-reactivity in COVID-19 Patients by Zaid, Younes, Khalki, Loubna, Jalali, Farid, Tijani, Youssef, Zaid, Nabil, Naya, Abdallah, Oudghiri, Mounia, Akarid, Khadija, Agbani, Ejaife O, Guessous, Fadila

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Aquaporins in platelet function by Agbani, Ejaife O., Poole, Alastair W.

“…Structurally, aquaporins (AQPs) are small channel proteins with monomers of ~ 30 kDa that are assembled as tetramers to form pores on cell membranes…”
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Temporal contribution of the platelet body and balloon to thrombin generation by Agbani, Ejaife O, Hers, Ingeborg, Poole, Alastair W

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Membrane Ballooning in Aggregated Platelets is Synchronised and Mediates a Surge in Microvesiculation by Agbani, Ejaife O., Williams, Christopher M., Hers, Ingeborg, Poole, Alastair W.

“…Human platelet transformation into balloons is part of the haemostatic response and thrombus architecture. Here we reveal that in aggregates of platelets in…”
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Natural history of antiplatelet nonresponders undergoing carotid artery stenting by Muram, Sandeep, Panchendrabose, Kapilan, Eagles, Matthew E, Salam, Mohammed S Abdul, Eesa, Muneer, Agbani, Ejaife O, Hill, Michael D, Riva-Cambrin, Jay, Mitha, Alim P

“…Routine antiplatelet responsiveness testing for patients undergoing carotid artery stenting procedures is not performed at most endovascular centers and…”
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Highly efficient platelet generation in lung vasculature reproduced by microfluidics by Zhao, Xiaojuan, Alibhai, Dominic, Walsh, Tony G., Tarassova, Nathalie, Englert, Maximilian, Birol, Semra Z., Li, Yong, Williams, Christopher M., Neal, Chris R., Burkard, Philipp, Cross, Stephen J., Aitken, Elizabeth W., Waller, Amie K., Beltrán, José Ballester, Gunning, Peter W., Hardeman, Edna C., Agbani, Ejaife O., Nieswandt, Bernhard, Hers, Ingeborg, Ghevaert, Cedric, Poole, Alastair W.

“…Platelets, small hemostatic blood cells, are derived from megakaryocytes. Both bone marrow and lung are principal sites of thrombopoiesis although underlying…”
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Opposing Roles of GSK3α and GSK3β Phosphorylation in Platelet Function and Thrombosis by Moore, Samantha F, Agbani, Ejaife O, Wersäll, Andreas, Poole, Alastair W, Williams, Chris M, Zhao, Xiaojuan, Li, Yong, Hutchinson, James L, Hunter, Roger W, Hers, Ingeborg

“…One of the mechanisms by which PI3 kinase can regulate platelet function is through phosphorylation of downstream substrates, including glycogen synthase…”
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Proteomics and Metabolomics Profiling of Platelets and Plasma Mediators of Thrombo-Inflammation in Gestational Hypertension and Preeclampsia by de Almeida, Luiz Gustavo N, Young, Daniel, Chow, Lorraine, Nicholas, Joshua, Lee, Adrienne, Poon, Man-Chiu, Dufour, Antoine, Agbani, Ejaife O

“…Platelets may be pivotal mediators of the thrombotic and coagulopathic complications of preeclampsia (PE), linking inflammation and thrombosis with endothelial…”
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Procoagulant platelets: generation, function, and therapeutic targeting in thrombosis by Agbani, Ejaife O., Poole, Alastair W.

“…Current understanding of how platelets localize coagulation to wound sites has come mainly from studies of a subpopulation of activated platelets. In this…”
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Membrane procoagulation and N‑terminomics/TAILS profiling in Montreal platelet syndrome kindred with VWF p.V1316M mutation by Agbani, Ejaife O., Young, Daniel, Chen, Si An, Smith, Sophie, Lee, Adrienne, Poole, Alastair W., Dufour, Antoine, Poon, Man-Chiu

“…Background The Montreal platelet syndrome kindred (MPS) with VWF p.V1316M mutation (2B-VWDMPS) is an extremely rare disorder. It has been associated with…”
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Letter by Agbani et al Regarding Article, “Clot Contraction Drives the Translocation of Procoagulant Platelets to Thrombus Surface” by Agbani, Ejaife O, Hers, Ingeborg, Poole, Alastair W

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Preeclampsia: Platelet procoagulant membrane dynamics and critical biomarkers by Agbani, Ejaife O., Skeith, Leslie, Lee, Adrienne

“…A state-of-the-art lecture titled “Preeclampsia and Platelet Procoagulant Membrane Dynamics” was presented at the International Society on Thrombosis and…”
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Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets by Agbani, Ejaife O, van den Bosch, Marion T.J, Brown, Ed, Williams, Christopher M, Mattheij, Nadine J.A, Cosemans, Judith M.E.M, Collins, Peter W, Heemskerk, Johan W.M, Hers, Ingeborg, Poole, Alastair W

“…BACKGROUND—Platelets are central to the process of hemostasis, rapidly aggregating at sites of blood vessel injury and acting as coagulation nidus sites. On…”
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Factor V Leiden (R506Q), Prothrombin G20210A, and MTHFR C677T Variants and Thrombophilia in Qatar Biobank Participants: A Case Control Study by Shibeeb, Sapha, Al-Rayashi, Nada, Shams, Nehal, Hadvan, Tameem, Agbani, Ejaife O, Abdallah, Atiyeh M

“…Thrombophilia, a predisposition to develop blood clots, is very common and can have serious sequelae. This study aimed to determine the prevalence of three…”
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Platelets and neutrophils co-drive procoagulant potential in secondary antiphospholipid syndrome during pregnancy by Agbani, Ejaife O., Mahe, Etienne, Chaturvedi, Shruti, Yamaura, Lisa, Schneider, Prism, Barber, Megan R.W., Choi, May, Lee, Adrienne, Skeith, Leslie

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Aquaporin-1 regulates platelet procoagulant membrane dynamics and in vivo thrombosis by Agbani, Ejaife O., Williams, Christopher M., Li, Yong, van den Bosch, Marion T.J., Moore, Samantha F., Mauroux, Adele, Hodgson, Lorna, Verkman, Alan S., Hers, Ingeborg, Poole, Alastair W.

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Platelet procoagulant membrane dynamics: a key distinction between thrombosis and hemostasis? by Agbani, Ejaife O., Hers, Ingeborg, Poole, Alastair W.

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Overexpression of facilitative glucose transporter-3 and membrane procoagulation in maternal platelets of preeclamptic pregnancy by Agbani, Ejaife O., Chow, Lorraine, Nicholas, Joshua, Skeith, Leslie, Schneider, Prism, Gregory, Alexander, Mahe, Etienne, Yamaura, Lisa, Young, Daniel, Dufour, Antoine, Paul, Padma Polash, Walker, Andrew M., Mukherjee, Priyanka G., Poole, Alastair W., Poon, Man-Chiu, Lee, Adrienne

“…Preeclampsia (PE) is a hypertensive disorder during pregnancy that results in significant adverse maternal and neonatal outcomes. Platelet activation is…”
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The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin αIIbβ3 Outside-in Signaling by Battram, Anthony M., Durrant, Tom N., Agbani, Ejaife O., Heesom, Kate J., Paul, David S., Piatt, Raymond, Poole, Alastair W., Cullen, Peter J., Bergmeier, Wolfgang, Moore, Samantha F., Hers, Ingeborg

“…The class I PI3K family of lipid kinases plays an important role in integrin αIIbβ3 function, thereby supporting thrombus growth and consolidation. Here, we…”
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Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis: Carbonic Anhydrase Inhibitors as Antithrombotics by Agbani, Ejaife O., Zhao, Xiaojuan, Williams, Christopher M., Aungraheeta, Riyaad, Hers, Ingeborg, Swenson, Erik R., Poole, Alastair W.

“…Carbonic anhydrase (CA) inhibitors have a long history of safe clinical use as mild diuretics, in the treatment of glaucoma and for altitude sickness…”
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