Impact of an antibiotic restriction program on antibiotic utilization in the treatment of community-acquired pneumonia in a Veterans Affairs Medical Center

Impact of an antibiotic restriction program on antibiotic utilization in the treatment of community-acquired pneumonia in a Veterans Affairs Medical Center

Purpose The impact of an antibiotic restriction program (ARP) on the patterns of antibiotic use in the treatment of community-acquired pneumonia (CAP) was examined. We also evaluated the association between the ARP and the length of hospital stay in regard to CAP treatment and cost savings associate...

Full description

Saved in:
Bibliographic Details
Published in:Infection Vol. 39; no. 1; pp. 53 - 58
Main Authors: Mansouri, M. D, Cadle, R. M, Agbahiwe, S. O, Musher, D. M
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Berlin/Heidelberg : Springer-Verlag 01-02-2011
Springer-Verlag
Springer
Springer Nature B.V
Subjects:
Aged
Aged, 80 and over
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - economics
Antibiotic restriction program
Antibiotics
Biological and medical sciences
Brief Report
Cohort Studies
Community-Acquired Infections - drug therapy
Drug Utilization - economics
Drug Utilization - standards
Drug Utilization - statistics & numerical data
Family Medicine
Female
General Practice
Health Care Costs
Hospital
Hospitals, Veterans
Humans
infection
Infectious Diseases
Internal Medicine
Length of Stay
Male
Medical sciences
Medicine
Medicine & Public Health
Middle Aged
Miscellaneous
Pneumonia - drug therapy
Public health. Hygiene
Public health. Hygiene-occupational medicine
Retrospective Studies
Treatment Outcome
Infection
Hospital
Antibiotics
Antibiotic restriction program
Prescription
Nosocomial infection
Costs
Pneumonia
Methodology
Residence time
Retrospective
Computer science
Antibiotic
Survey
Treatment
Hygiene
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose The impact of an antibiotic restriction program (ARP) on the patterns of antibiotic use in the treatment of community-acquired pneumonia (CAP) was examined. We also evaluated the association between the ARP and the length of hospital stay in regard to CAP treatment and cost savings associated with the implementation of the ARP. Methods A retrospective cohort study of patients admitted with CAP was conducted during two 6-month periods, one prior to the ARP and one after the ARP. The health system's computerized patient record system (CPRS) was used to obtain demographics, length of hospital stays, readmission rates, blood culture results, co-morbidities, antibiotic use, and durations of therapy. A total of 130 patients met the inclusion criteria for the final analyses. Average drug costs, employee salaries, and the cost of laboratory procedures were used to assess cost savings associated with the ARP. Results From a total of 132 antibiotics that were ordered to treat CAP in the pre-ARP period, 28 were restricted (21.2%). However, the number of restricted antibiotics ordered was significantly reduced to 12 out of 114 (10.2%) antibiotics ordered in the post-ARP period (P = 0.024). In post-ARP implementation, the mean length of hospital stay was also significantly reduced from 7.6 to 5.8 days (P = 0.017), and although not statistically significant, the 30-day readmission rates declined from 16.9 to 6.2% (P = 0.097). The ARP was also associated with a saving of $943 per patient treated for CAP. Conclusions In addition to a decrease in the antibiotic utilization and the mean length of hospital stay, the ARP may have yielded cost savings and reduced the readmission rates for those patients admitted and treated for CAP.
Bibliography:http://dx.doi.org/10.1007/s15010-010-0078-0
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0300-8126
1439-0973
DOI:10.1007/s15010-010-0078-0