Search Results - "Agathanggelou, A"

BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia by Da Costa, D, Agathanggelou, A, Perry, T, Weston, V, Petermann, E, Zlatanou, A, Oldreive, C, Wei, W, Stewart, G, Longman, J, Smith, E, Kearns, P, Knapp, S, Stankovic, T

“…Paediatric B-precursor ALL is a highly curable disease, however, treatment resistance in some patients and the long-term toxic effects of current therapies…”
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Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours by AGATHANGGELOU, Angelo, HONORIO, Sofia, HOSOE, Shigeto, LERMAN, Michael I, MINNA, John D, MAHER, Eamonn R, LATIF, Farida, MACARTNEY, Donia P, MARTINEZ, Alonso, DALLOL, Ashraf, RADER, Janet, FULLWOOD, Paul, CHAUHAN, Anita, WALKER, Rosemary, SHAW, Jacqueline A

“…Previously we analysed overlapping homozygous deletions in lung and breast tumours/tumour lines and defined a small region of 120 kb (part of LCTSGR1) at…”
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Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma by Hogg, R.P, Honorio, S, Martinez, A, Agathanggelou, A, Dallol, A, Fullwood, P, Weichselbaum, R, Kuo, M.J, Maher, E.R, Latif, F

“…Studies of allelic imbalance and suppression of tumourigenicity have consistently suggested that the short arm of chromosome three (3p) harbours tumour…”
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Identification of the E1A-regulated transcription factor p120(E4F) as an interacting partner of the RASSF1A candidate tumor suppressor gene by Fenton, S. L., Dallol, A., Agathanggelou, A., Hesson, L., Ahmed-Choudhury, J., Baksh, S., Sardet, C., Dammann, R., Minna, J. D., Downward, J., Maher, E. R., Latif, F.

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2.2 Controlled Depletion of Autologous T Cells Facilitates a Lasting CLL Proliferation in the CLL Xenograft Model by Skowronska, A, Odreive, C, Agathanggelou, A, Pratt, G, Moss, P, Taylor, A.M.R, Stankovic, T

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5.2 Combinatory Effect of PARP Inhibition with Existing Low-Toxicity Chromatin Modifying Agents (HDAC Inhibitors) Sensitizes CLL Tumors with DNA Damage Response Defect by Stankovic, T, Agathanggelou, A, Oldreive, C, Weston, V, Moss, P, Taylor, A, Pratt, G

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Frequent expression of interleukin-10 by Epstein-Barr virus-harboring tumor cells of Hodgkin's disease by HERBST, H, FOSS, H.-D, SAMOL, J, ARAUJO, I, KLOTZBACH, H, KRAUSE, H, AGATHANGGELOU, A, NIEDOBITEK, G, STEIN, H

“…Tumor cells of Epstein-Barr virus (EBV)-associated Hodgkin's disease (HD) express the viral protein, latent infection membrane protein-1 (LMP1), but evade…”
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1.1 Inhibition of Deubiquitinating Enzyme USP7 Sensitizes CLL Tumor with ATM and p53 Dysfunction by Targeting Both Mdm2/p53 Loop and DNA Repair by Agathanggelou, A, Zlatanou, N, Gulshanara, A, Stewart, G, Pratt, G, Taylor, A, Colland, F, Stankovic, T

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Heterogeneous Expression of Epstein-Barr Virus Latent Proteins in Endemic Burkitt's Lymphoma by Niedobitek, G., Agathanggelou, A., Rowe, M., Jones, E.L., Jones, D.B., Turyaguma, P., Oryema, J., Wright, D.H., Young, L.S.

“…Epstein-Barr virus (EBV)-infected cells may sustain three distinct forms of virus latency. In lymphoblastoid cell lines, six EBV-encoded nuclear antigens…”
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Expression of immune regulatory molecules in Epstein-Barr virus- associated nasopharyngeal carcinomas with prominent lymphoid stroma. Evidence for a functional interaction between epithelial tumor cells and infiltrating lymphoid cells by Agathanggelou, A, Niedobitek, G, Chen, R, Nicholls, J, Yin, W, Young, LS

“…Undifferentiated nasopharyngeal carcinomas (UNPC) are characterized by an association with Epstein-Barr virus and an abundant lymphoid stroma. The role of this…”
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Epstein-Barr virus (EBV) in infectious mononucleosis: detection of the virus in tonsillar B lymphocytes but not in desquamated oropharyngeal epithelial cells by Niedobitek, G, Agathanggelou, A, Steven, N, Young, L S

“…Aims—Despite its well established tropism for B cells, the nature of the cellular compartment(s) mediating primary and persistent Epstein-Barr virus (EBV)…”
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Role of the ras-association domain family 1 tumor suppressor gene in human cancers by AGATHANGGELOU, Angelo, COOPER, Wendy N, LATIF, Farida

“…In recent years, the list of tumor suppressor genes (or candidate TSG) that are inactivated frequently by epigenetic events rather than classic…”
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Identification of a single nucleotide polymorphism in the human alpha 2 delta 2 calcium channel subunit gene by Honorio, S., Gordon, K., MacCartney, D., Agathanggelou, A., Latif, F.

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Non-Hodgkin's lymphoma, coeliac disease, and Epstein-Barr virus: a study of 13 cases of enteropathy-associated T- and B-cell lymphoma by Ilyas, M, Niedobitek, G, Agathanggelou, A, Barry, R E, Read, A E, Tierney, R, Young, L S, Rooney, N

“…A group of 166 patients with coeliac disease was followed for a period of up to 25 years. During this time, 17 patients developed intestinal tumours that were…”
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Latent Epstein-Barr virus infection in cottontop tamarins. A possible model for Epstein-Barr virus infection in humans by Niedobitek, G, Agathanggelou, A, Finerty, S, Tierney, R, Watkins, P, Jones, EL, Morgan, A, Young, LS, Rooney, N

“…The association of Epstein-Barr virus (EBV) with a growing number of human malignancies underlines the importance of efforts aimed at preventing the infection…”
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The expression of variant CD44 in nasopharyngeal carcinoma is unrelated to expression of LMP-1 by Brooks, L, Niedobitek, G, Agathanggelou, A, Farrell, PJ

“…CD44 expression in undifferentiated nasopharyngeal carcinoma has been analyzed by sequencing cDNA clones and by immunohistochemical staining using monoclonal…”
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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants by Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R, Stankovic, Tatjana

“…Inactivation of the Ataxia Telangiectasia Mutated gene in chronic lymphocytic leukemia results in resistance to p53-dependent apoptosis and inferior responses…”
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Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma by MORRISSEY, Catherine, MARTINEZ, Alonso, YAO, Masahiro, SCHRAML, Peter, LATIF, Farida, MAHER, Eamonn R, ZATYKA, Malgorzata, AGATHANGGELOU, Angelo, HONORIO, Sofia, ASTUTI, Dewi, MORGAN, Neil V, MOCH, Holger, RICHARDS, Frances M, KISHIDA, Takeshi

“…Renal cell carcinoma (RCC), the most common adult kidney neoplasm, is histopathologically heterogeneous, with most sporadic RCCs ( approximately 80%)…”
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Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours by HONORIO, Sofia, AGATHANGGELOU, Angelo, WERNERT, Nicolas, ROTHE, Marcus, MAHER, Eamonn R, LATIF, Farida

“…Testicular germ cell tumours (TGCTs) are histologically heterogeneous neoplasms with variable malignant potential. Previously, we demonstrated frequent 3p…”
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Involvement of the RASSF1A tumor suppressor gene in controlling cell migration by DALLOL, Ashraf, AGATHANGGELOU, Angelo, TOMMASI, Stella, PFEIFER, Gerd P, MAHER, Eamonn R, LATIF, Farida

“…We have previously shown that RASSF1A associates with the microtubules. This association alters the microtubule dynamics and seems essential for RASSF1A tumor…”
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