Search Results - "Agata, N N"

Effects of Tumour Necrosis Factor Antagonists on Insulin Sensitivity/Resistance in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis by Burska, Agata N, Sakthiswary, Rajalingham, Sattar, Naveed

“…Beyond the joints, TNFi (tumour necrosis factor inhibitor) therapy may confer systemic benefits in rheumatoid arthritis (RA). Several studies have investigated…”
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Autophagy Brings an END to Aberrant Endocytosis by Makar, Agata N., Gammoh, Noor

“…Wilfling et al. (2020) characterize a selective autophagy pathway in yeast for early clathrin-mediated endocytosis (CME) proteins facilitated by the phase…”
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Age-related Changes in Bone Marrow Mesenchymal Stromal Cells: A Potential Impact on Osteoporosis and Osteoarthritis Development by Ganguly, Payal, El-Jawhari, Jehan J., Giannoudis, Peter V., Burska, Agata N., Ponchel, Frederique, Jones, Elena A.

“…Aging at the cellular level is a complex process resulting from accumulation of various damages leading to functional impairment and a reduced quality of life…”
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Membrane targeting of core autophagy players during autophagosome biogenesis by Dudley, Leo J., Makar, Agata N., Gammoh, Noor

“…Autophagosomes are vital organelles required to facilitate the lysosomal degradation of cytoplasmic cargo, thereby playing an important role in maintaining…”
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Lighting up mRNA localization in Drosophila oogenesis by Becalska, Agata N, Gavis, Elizabeth R

“…The asymmetric localization of four maternal mRNAs - gurken, bicoid, oskar and nanos - in the Drosophila oocyte is essential for the development of the…”
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Helminths of the black-headed gull (Chroicocephalus ridibundus) from breeding colonies in north-central Poland by Stapf, Agata N., Rząd, Izabella, Królaczyk, Katarzyna, Indykiewicz, Piotr, Gruszka, Wojciech

“…Among parasites of the digestive tract of the black-headed gull ( Chroicocephalus ridibundus ) in Poland, the best known are species of digenetic trematodes…”
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The V-ATPase complex component RNAseK is required for lysosomal hydrolase delivery and autophagosome degradation by Makar, Agata N., Boraman, Alina, Mosen, Peter, Simpson, Joanne E., Marques, Jair, Michelberger, Tim, Aitken, Stuart, Wheeler, Ann P., Winter, Dominic, von Kriegsheim, Alex, Gammoh, Noor

“…Autophagy is a finely orchestrated process required for the lysosomal degradation of cytosolic components. The final degradation step is essential for clearing…”
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Phase separation in polymer-based biomimetic structures containing planar membranes by Bina, Maryame, Sciortino, Flavien, Mahrir, Agata N

“…Phase separation in biological membranes is crucial for proper cellular functions, such as signaling and trafficking, as it mediates the interactions of…”
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Intrinsic lipid binding activity of ATG16L1 supports efficient membrane anchoring and autophagy by Dudley, Leo J, Cabodevilla, Ainara G, Makar, Agata N, Sztacho, Martin, Michelberger, Tim, Marsh, Joseph A, Houston, Douglas R, Martens, Sascha, Jiang, Xuejun, Gammoh, Noor

“…Membrane targeting of autophagy‐related complexes is an important step that regulates their activities and prevents their aberrant engagement on non‐autophagic…”
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Interferon-related gene expression in response to TNF inhibitor treatment in ankylosing spondylitis patients: a pilot study by Harrison, Stephanie R, Burska, Agata N, Emery, Paul, Marzo-Ortega, Helena, Ponchel, Frederique

“…Ankylosing spondylitis (AS) is a chronic inflammatory arthritis primarily affecting the spine and sacroiliac joints. TNF inhibitor (TNFi) drugs are recommended…”
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Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells by Funk, Maja C, Bera, Agata N, Menchen, Tabea, Kuales, Georg, Thriene, Kerstin, Lienkamp, Soeren S, Dengjel, Jörn, Omran, Heymut, Frank, Marcus, Arnold, Sebastian J

“…Mucociliary clearance and fluid transport along epithelial surfaces are carried out by multiciliated cells (MCCs). Recently, human mutations in Cyclin O ( CCNO…”
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How Have Leukocyte In Vitro Chemotaxis Assays Shaped Our Ideas about Macrophage Migration? by Rumianek, Agata N, Greaves, David R

“…Macrophage chemotaxis is crucial during both onset and resolution of inflammation and unique among all leukocytes. Macrophages are able to switch between…”
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The Vitamin C Enantiomers Possess a Comparable Potency in the Induction of Oxidative Stress in Cancer Cells but Differ in Their Toxicity by Begimbetova, Dinara, Burska, Agata N, Baltabekova, Aidana, Kussainova, Assiya, Kukanova, Assiya, Fazyl, Fatima, Ibragimova, Milana, Manekenova, Kenzhekyz, Makishev, Abay, Bersimbaev, Rakhmetkazhi I, Sarbassov, Dos D

“…The use of vitamin C (VC) in high doses demonstrates a potent tumor suppressive effect by mediating a glucose-dependent oxidative stress in Kirsten rat sarcoma…”
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Synovial Tissue Heterogeneity in Rheumatoid Arthritis and Changes With Biologic and Targeted Synthetic Therapies to Inform Stratified Therapy by Ouboussad, Lylia, Burska, Agata N, Melville, Andrew, Buch, Maya H

“…The treatment of rheumatoid arthritis (RA) has been transformed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARD) and more…”
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Quantifying circulating Th17 cells by qPCR: potential as diagnostic biomarker for rheumatoid arthritis by Burska, Agata N, Thu, Aye, Parmar, Rekha, Bzoma, Izabella, Samans, Bjoern, Raschke, Eva, Olek, Sven, Conaghan, Philip G, Emery, Paul, Ponchel, Frederique

“…Abstract Objective The diagnosis of RA patients remains a challenge, especially in ACPA-negative disease. Novel T-cell subsets, particularly Th17 may be…”
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Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals by Walsh, Rylie B, Dresselhaus, Erica C, Becalska, Agata N, Zunitch, Matthew J, Blanchette, Cassandra R, Scalera, Amy L, Lemos, Tania, Lee, So Min, Apiki, Julia, Wang, ShiYu, Isaac, Berith, Yeh, Anna, Koles, Kate, Rodal, Avital A

“…Neuronal extracellular vesicles (EVs) play important roles in intercellular communication and pathogenic protein propagation in neurological disease. However,…”
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T-cell subset abnormalities predict progression along the Inflammatory Arthritis disease continuum: implications for management by Ponchel, Frederique, Burska, Agata N., Hunt, Laura, Gul, Hanna, Rabin, Thibault, Parmar, Rekha, Buch, Maya H., Conaghan, Philip G., Emery, Paul

“…The presence of a disease continuum in inflammatory arthritis (IA) is a recognised concept, with distinct stages from at-risk stage (presence of anti…”
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Gene expression and functional comparison between multipotential stromal cells from lateral and medial condyles of knee osteoarthritis patients by Sanjurjo-Rodriguez, Clara, Baboolal, Thomas G., Burska, Agata N., Ponchel, Frederique, El-Jawhari, Jehan J., Pandit, Hemant, McGonagle, Dennis, Jones, Elena

“…Osteoarthritis (OA) is the most common degenerative joint disorder. Multipotential stromal cells (MSCs) have a crucial role in joint repair, but how OA…”
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A Human CD68 Promoter-Driven Inducible Cre-Recombinase Mouse Line Allows Specific Targeting of Tissue Resident Macrophages by Rumianek, Agata N, Davies, Ben, Channon, Keith M, Greaves, David R, Purvis, Gareth S D

“…Current genetic tools designed to target macrophages often target cells from all myeloid lineages. Therefore, we sought to generate a novel transgenic mouse…”
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Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis by Ponchel, Frédérique, Emery, Paul, Nissim, Ahuva, Vital, Ed, Ryan, Brent J., Strollo, Rocky, Boissinot, Marjorie, Hunt, Laura, Burska, Agata N., Winyard, Paul G.

“…Autoantibodies have been associated with human pathologies for a long time, particularly with autoimmune diseases (AIDs). Rheumatoid factor (RF) is known since…”
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