Search Results - "Agarwal, Shiuli"
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The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans
Published in Nature communications (11-12-2020)“…Long non-coding RNAs are important regulators of biological processes including immune responses. The immunoregulatory functions of lncRNAs have been revealed…”
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Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2
Published in Cell reports (Cambridge) (06-11-2018)“…An inducible gene expression program is a hallmark of the host inflammatory response. Recently, long intergenic non-coding RNAs (lincRNAs) have been shown to…”
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The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2
Published in Proceedings of the National Academy of Sciences - PNAS (03-01-2023)“…The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative feedback regulator of type I interferon and inflammatory cytokine…”
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Abstract 4933: Novel insight into hallmark switch in cancer metabolism using the Interrogative Biology™ discovery platform
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Cancer metabolism is an intergrative ensemble of disrupted enzyme kinetics and dysregulated metabolite utilization leading to loss of normal cellular function…”
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