Search Results - "Agardh, Hanna E"
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Sustained Inflammation Due to Nuclear Factor-Kappa B Activation in Irradiated Human Arteries
Published in Journal of the American College of Cardiology (23-03-2010)“…Objectives The aim of this study was to investigate gene expression networks related to cardiovascular disease in radiated human arteries. Background Recent…”
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Journal Article -
2
Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response
Published in Proceedings of the National Academy of Sciences - PNAS (21-04-2015)“…The B-cell response in atherosclerosis is directed toward oxidation-specific epitopes such as phosphorylcholine (PC) that arise during disease-driven oxidation…”
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Journal Article -
3
Expression of 5-Lipoxygenase and Leukotriene A₄ Hydrolase in Human Atherosclerotic Lesions Correlates with Symptoms of Plaque Instability
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2006)“…Leukotrienes (LT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of atherosclerosis. Here we report…”
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Journal Article -
4
Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2013)“…Obesity promotes a chronic inflammatory condition in adipose tissue (AT). Impairment of insulin sensitivity coincides with infiltration of T cells into AT in…”
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Journal Article -
5
Endogenous control genes in complex vascular tissue samples
Published in BMC genomics (10-11-2009)“…Gene expression microarrays and real-time PCR are common methods used to measure mRNA levels. Each method has a fundamentally different approach of…”
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Journal Article -
6
Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy
Published in Molecular medicine (Cambridge, Mass.) (2012)“…Classic risk factors, including age, smoking, serum cholesterol, diabetes and blood pressure, constitute the basis of present risk prediction models but fail…”
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Journal Article -
7
Association of Genetic Risk Variants With Expression of Proximal Genes Identifies Novel Susceptibility Genes for Cardiovascular Disease
Published in Circulation. Cardiovascular genetics (01-08-2010)“…BACKGROUND—Population-based genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with cardiovascular…”
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Journal Article -
8
Fatty acid binding protein 4 in circulating leucocytes reflects atherosclerotic lesion progression in Apoe−/− mice
Published in Journal of cellular and molecular medicine (01-02-2013)“…Discovery of novel biomarkers for atherosclerosis is important to aid in early diagnosis of pre‐symptomatic patients at high risk of cardiovascular events. The…”
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Journal Article -
9
Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions
Published in Atherosclerosis (01-02-2007)“…Abstract Heparan sulfate in the extracellular matrix of the artery wall has been proposed to possess anti-atherogenic properties by interfering with…”
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Journal Article -
10
Expression of 5-lipoxygenase and leukotriene A^sub 4^ hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2006)“…Leukotrienes (IT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of atherosclerosis. Here we report…”
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Journal Article -
11
Identification of Inflammatory Genes Involved in the Pathogenesis of Human and Experimental Atherosclerosis
Published 01-01-2012“…Atherosclerosis is a chronic systemic inflammatory disease of large and medium sized arteries, developing slowly and silently over decades. The disease is…”
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Dissertation -
12
Expression of 5-lipoxygenase and leukotriene A sub(4) hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2006)“…Leukotrienes (LT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of atherosclerosis. Here we report…”
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Journal Article -
13
Expression of 5-lipoxygenase and leukotriene A 4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-2006)“…Leukotrienes (LT) are a group of proinflammatory lipid mediators that are implicated in the pathogenesis and progression of atherosclerosis. Here we report…”
Get full text
Journal Article