Search Results - "Agapkina, Yu Yu"

SFPQ and NONO Proteins and Long Non-Coding NEAT1 RNA: Cellular Functions and Role in the HIV-1 Life Cycle by Shadrina, O. A., Kikhay, T. F., Agapkina, Yu. Yu, Gottikh, M. B.

“…About 20 years ago, large RNA–protein complexes called paraspeckles were discovered in cell nuclei. The main components of these complexes are SFPQ and NONO…”
Get full text

Characterization of HIV-1 integrase interaction with human Ku70 protein and initial implications for drug targeting by Anisenko, Andrey N., Knyazhanskaya, Ekaterina S., Zalevsky, Artur O., Agapkina, Julia Yu, Sizov, Aleksander I., Zatsepin, Timofey S., Gottikh, Marina B.

“…Human Ku70/Ku80 protein is known to influence HIV-1 replication. One of the possible reasons may be the protection of integrase from proteasomal degradation by…”
Get full text

Nitrobenzofuroxane derivatives as dual action HIV-1 inhibitors by Korolev, S. P., Pustovarova, M. A., Starosotnikov, A. M., Bastrakov, M. A., Agapkina, Yu. Yu, Shevelev, S. A., Gottikh, M. B.

“…Human immunodeficiency virus type 1 (HIV-1) causes one of the most dangerous diseases, HIV infection and AIDS. The search for new inhibitors of the virus still…”
Get full text

Influence of Drug Resistance Mutations on the Activity of HIV-1 Subtypes A and B Integrases: a Comparative Study by Shadrina, O A, Zatsepin, T S, Agapkina, Yu Yu, Isaguliants, M G, Gottikh, M B

“…Integration of human immunodeficiency virus (HIV-1) DNA into the genome of an infected cell is one of the key steps in the viral replication cycle. The viral…”
Get full text

Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects by Korolev, S P, Agapkina, Yu Yu, Gottikh, M B

“…The HIV-1 integrase enzyme is responsible for one of the key stages of retroviral replication; it acts as a catalyst for the integration of viral cDNA into the…”
Get full text

Isolation and structure of a novel peptide inhibitor of HIV-1 integrase from marine polychaetes by Elyakova, L. A., Vaskovsky, B. V., Khoroshilova, N. I., Vantseva, S. I., Agapkina, Yu. Yu

“…A homogeneous peptide with a mass of 683 Da which inhibits HIV-1 integrase with IC 50 3 × 10 −5 M was separated from aqueous extracts of a marine worm…”
Get full text

polymorphisms G(−174)C in IL6 gene and G(−1082)A in IL10 gene are associated with poor outcomes in patients with acute coronary syndrome by Blagodatskikh, K. A, Evdokimova, M. A, Agapkina, Yu. V, Nikitin, A. G, Brovkin, A. N, Pushkov, A. A, Blagodatskikh, E. G, Kudryashova, O. Yu, Osmolovskaya, V. S, Minushkina, L. O, Kochkina, M. S, Selezneva, N. D, Dankovtseva, E. N, Chumakova, O. S, Baklanova, T. N, Talyzin, P. A, Reznichenko, N. E, Donetskaya, O. P, Tereshchenko, S. N, Krasil'nikova, E. S, Dzhaiani, N. A, Akatova, E. V, Glezer, M. G, Galyavich, A. S, Zakirova, V. B, Koziolova, N. A, Timofeeva, I. V, Yagoda, A. V, Boeva, O. I, Katel'nitskaya, L. I, Khorolets, E. V, Shlyk, S. V, Volkova, E. G, Margaryan, M. P, Guz', I. O, Konstantinov, V. O, Timofeeva, N. V, Sidorenko, B. A, Zateishchikov, D. A, Nosikov, V. V

“…Association between the rates of poor outcomes in the patient cohort with acute coronary syndrome and polymorphisms G(−174)C in the IL6 gene and G(−1082)A in…”
Get full text

HIV-1 integrase inhibition by dimeric bisbenzimidazoles with different spacer structures by Korolev, S. P, Tashlitsky, V. N, Smolov, M. A, Gromyko, A. V, Zhuze, A. L, Agapkina, Yu. Yu, Gottikh, M. B

“…HIV-1 integrase is responsible for one of the key stages in virus replication, namely, integration of viral cDNA into the host cell genome. Integration…”
Get full text

Association of the polymorphic markers G(−455)A in the FGB gene and C(−1654)T in the PROC gene with hereditary predisposition to unfavourable outcome in patients with history of acute coronary syndrome by Agapkina, Yu. V, Nikitin, A. G, Brovkin, A. N, Pushkov, A. A, Evdokimova, M. A, Aseycheva, O. Yu, Osmolovskaya, V. S, Minushkina, L. O, Kochkina, M. S, Selezneva, N. D, Dankovtseva, E. N, Chumakova, O. S, Baklanova, T. N, Talyzin, P. A, Reznichenko, N. E, Donetskaya, O. P, Tereschenko, S. N, Krasil'nikova, E. S, Dzhaiani, N. A, Akatova, E. V, Glezer, M. G, Galyavich, A. S, Zakirova, V. B, Koziolova, N. A, Timofeeva, I. V, Yagoda, A. V, Boyeva, O. I, Katelnitskaya, L. I, Horolets, E. V, Shlyk, S. V, Volkova, E. G, Margaryan, M. P, Guz, I. O, Konstantinov, V. O, Timofeyeva, A. N, Sidorenko, B. A, Zateyshchikov, D. A, Nosikov, V. V

“…Associations of polymorphisms of genes FGB G(−455)A and PROC C(−1654)T with the frequency of poor outcomes in patients with the history of acute coronary…”
Get full text

Polymorphic markers Ala455Val of the THBD gene and Arg353Gln of the F7 gene and genetic association with unfavorable outcomes of coronary atherosclerosis in patients with a history of acute ischemic heart disease by Pushkov, A. A., Blagodatskikh, K. A., Nikitin, A. G., Agapkina, Yu. V., Brovkin, A. N., Chudakova, D. A., Evdokimova, M. A., Aseycheva, O. Yu, Osmolovskaya, V. S., Minushkina, L. O., Baklanova, T. N., Talyzin, P. A., Donetskaya, O. P., Tereschenko, S. N., Dzhaiani, N. A., Akanova, E. V., Glezer, M. G., Galyavich, A. S., Zakirova, V. B., Koziolova, N. A., Yagoda, A. V., Boyeva, O. I., Horolets, E. V., Shlyk, S. V., Volkova, E. G., Margaryan, M. P., Guz, I. O., Konstantinov, V. O., Sidorenko, B. A., Zeteyshchikov, D. A., Nosikov, V. V.

“…The polymorphic markers Ala455Val of the THBD gene and Arg353Gln of the F7 gene were tested for association with the frequency of unfavorable outcomes in…”
Get full text

Consensus Integrase of a New HIV-1 Genetic Variant CRF63_02A1 by Agapkina, Y Y, Pustovarova, M A, Korolev, S P, Zyryanova, D P, Ivlev, V V, Totmenin, A V, Gashnikova, N M, Gottikh, M B

“…The high genetic variability of the human immunodeficiency virus (HIV-1) leads to a constant emergence of new genetic variants, including the recombinant virus…”
Get full text

Nitrobenzofuroxane derivatives as dual action hiv-1 inhibitors by Korolev, S P, Pustovarova, M A, Starosotnikov, A M, Bastrakov, M A, Agapkina, Yu Yu, Shevelev, S A, Gottikh, M B

“…Human immunodeficiency virus first type (HIV-1) is a main cause of one of the most dangerous diseases, AIDS. The search for new inhibitors of the virus still…”
Get more information

Role of I182, R187, and K188 Amino Acid Residues in the Catalytic Domain of HIV-1 Integrase in the Processes of Reverse Transcription and Integration by Kikhai, Tatiana F., Agapkina, Yulia Yu, Prikazchikova, Tatiana A., Vdovina, Maria V., Shekhtman, Sofia P., Fomicheva, Sofia V., Korolev, Sergey P., Gottikh, Marina B.

“…Structural organization of HIV-1 integrase is based on a tetramer formed by two protein dimers. Within this tetramer, the catalytic domain of one subunit of…”
Get full text

DNA sequence-specific ligands. XVIII. Synthesis, physico-chemical properties; genetic, virological, and biochemical studies of fluorescent dimeric bisbenzimidazoles DBPA(n) by Koval, Vasiliy S., Arutyunyan, Albert F., Salyanov, Victor I., Kostyukov, Alexey A., Melkina, Olga E., Zavilgelsky, Gennadii B., Klimova, Regina R., Kushch, Alla A., Korolev, Sergey P., Agapkina, Yulia Yu, Gottikh, Marina B., Vaiman, Andrey V., Rybalkina, Ekaterina Yu, Susova, Olga Yu, Zhuze, Alexei L.

“…[Display omitted] A set of AT-specific fluorescent dimeric bisbenzimidazoles DBPA(n) with linkers of different lengths bound to DNA in the minor groove were…”
Get full text

Genetic predisposition to unfavorable course of ischemic heart disease in patients after acute coronary syndrome by Zakirova, V B, Brovkin, A N, Galeeva, Z M, Nikitin, A G, Galiavich, A S, Agapkina, Iu V, Evdokimova, M A, Iakunina, N Iu, Osmolovskaia, V S, Aseĭcheva, O Iu, Nosikov, V V, Zateĭshchikov, D A

Get more information