Search Results - "Aganna, E"

Circulating MMP9, vitamin D and variation in the TIMP‐1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders? by Timms, P.M., Mannan, N., Hitman, G.A., Noonan, K., Mills, P.G., Syndercombe‐court, D., Aganna, E., Price, C.P., Boucher, B.J.

“…Background: Vitamin‐D deficiency and vitamin‐D receptor genotype (VDR) are risk factors for several disorders with inflammatory components, including coronary…”
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TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study by Gordon, A C, Lagan, A L, Aganna, E, Cheung, L, Peters, C J, McDermott, M F, Millo, J L, Welsh, K I, Holloway, P, Hitman, G A, Piper, R D, Garrard, C S, Hinds, C J

“…Tumour necrosis factor (TNF) is an important pro-inflammatory cytokine produced in sepsis. Studies examining the association of individual TNF single…”
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Allelic variation in the vitamin D receptor influences susceptibility to IDDM in Indian Asians by MCDERMOTT, M. F, RAMACHANDRAN, A, OGUNKOLADE, B. W, AGANNA, E, CURTIS, D, BOUCHER, B. J, SNEHALATHA, C, HITMAN, G. A

“…Vitamin D has important immunomodulatory properties and prevents development of diabetes mellitus in an animal model of insulin-dependent diabetes (IDDM). We…”
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Allelic variants in genes associated with hereditary periodic fever syndromes as susceptibility factors for reactive systemic AA amyloidosis by Aganna, E, Hawkins, P N, Ozen, S, Pettersson, T, Bybee, A, McKee, S A, Lachmann, H J, Karenko, L, Ranki, A, Bakkaloglu, A, Besbas, N, Topaloglu, R, Hoffman, H M, Hitman, G A, Woo, P, McDermott, M F

“…We investigated the hypothesis that low-penetrance mutations in genes (TNFRSF1A, MEFV and NALP3/CIAS1) associated with hereditary periodic fever syndromes…”
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Vitamin d receptor gene polymorphisms influence insulin secretion in Bangladeshi Asians by HITMAN, G. A, MANNAN, N, MCDERMOTT, M. F, AGANNA, E, OGUNKOLADE, B. W, HALES, C. N, BOUCHER, B. J

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Hyper IgD syndrome (HIDS) associated with in vitro evidence of defective monocyte TNFRSF1A shedding and partial response to TNF receptor blockade with etanercept by ARKWRIGHT, P. D., MCDERMOTT, M. F., HOUTEN, S. M., FRENKEL, J., WATERHAM, H. R., AGANNA, E., HAMMOND, L. J., MIRAKIAN, R. M., TOMLIN, P. I., VIJAYDURAI, P. I., CANT, A. J.

“…Summary Hereditary periodic fever syndromes comprise a group of distinct disease entities linked by the defining feature of recurrent febrile episodes. Hyper…”
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Periodic fever due to a novel TNFRSF1A mutation in a heterozygous Chinese carrier of MEFV E148Q by Stojanov, S., Lohse, P., McDermott, M. F., Renner, E. D., Kéry, A., Mirakian, R., Hammond, L. J., Aganna, E., Hoffmann, F., Zellerer, S., Belohradsky, B. H.

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Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a Dutch family: evidence for a TNFRSF1A mutation with reduced penetrance by Aganna, E, Aksentijevich, I, Hitman, G A, Kastner, D L, Hoepelman, A I, Posma, F D, Zweers, E J, McDermott, M F

“…Mutations of the tumor necrosis factor receptor 1 (TNFRSF1A) gene underly susceptibility to a subset of autosomal dominant recurrent fevers (ADRFs). We report…”
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Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study by Chowdhury, Z Md, McDermott, M F, Davey, S, Hassan, Z, Sinnott, P J, Hemmatpour, S K, Sherwin, S, Ali, L, Aganna, E, Allotey, R A, North, B V, Cassell, P G, Azad Khan, A K, Hitman, G A

“…Fibrocalculous pancreatic diabetes (FCPD) is an uncommon cause of diabetes, seen mainly in developing countries. A family-based study was carried out in 67…”
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Infevers: An evolving mutation database for auto-inflammatory syndromes by Touitou, Isabelle, Lesage, Suzanne, McDermott, Michael, Cuisset, Laurence, Hoffman, Hal, Dode, Catherine, Shoham, Nitza, Aganna, Ebun, Hugot, Jean-Pierre, Wise, Carol, Waterham, Hans, Pugnere, Denis, Demaille, Jacques, de Menthiere, Cyril Sarrauste

“…The Infevers database (http://fmf.igh.cnrs.fr/infevers/) was established in 2002 to provide investigators with access to a central source of information about…”
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F008: Relationship between metalloproteinase9 tissue inhibitor of metalloproteinase-1 and vitamin D status: Its relevance to ischaemic heart disease in asians by Timms, P.M., Mannan, N., Hitman, G.A., Aganna, E., Noonan, K., Mills, P.M., Syndercombe-Court, D., Patet, B., Price, C.P., Boucher, B.J.

“…Vitamin D deficiency is associated with hypertension and cardiovascular disease. Metalloproteinases (MMP) and their tissue inhibitors (TIMP) control tissue…”
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Tumour necrosis factor receptor associated periodic syndrome (TRAPS) with central nervous system involvement by Minden, K, Aganna, E, McDermott, M F, Zink, A

“…Tumour necrosis factor receptor associated periodic syndrome (TRAPS) is an autosomal dominant disorder resulting from mutations in the TNFRSF1A gene, 1…”
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Calpain facilitates actin reorganization during glucose-stimulated insulin secretion by Turner, Mark D., Fulcher, F. Kent, Jones, Cristina V., Smith, Bethany T., Aganna, Ebun, Partridge, Christopher J., Hitman, Graham A., Clark, Anne, Patel, Yashomati M.

“…Calpain-10 (CAPN10) has been identified as a diabetes susceptibility gene. Previous studies have shown that alterations in calpain activity alter both glucose…”
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Interaction between smoking and the glycoprotein IIIa P1(A2) polymorphism in non-ST-elevation acute coronary syndromes by Barakat, K, Kennon, S, Hitman, G A, Aganna, E, Price, C P, Mills, P G, Ranjadayalan, K, North, B, Clarke, H, Timmis, A D

“…The goal of this study was to determine the interaction between smoking and the glycoprotein IIIa P1(A2) polymorphism in patients admitted with…”
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Spectrum of clinical features in Muckle‐Wells syndrome and response to anakinra by Hawkins, Philip N., Lachmann, Helen J., Aganna, Ebun, McDermott, Michael F.

“…Objective Mutations in the NALP3/CIAS1/PYPAF1 gene are associated with the autoinflammatory diseases Muckle‐Wells syndrome (MWS), familial cold…”
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TNF RECEPTOR POLYMORPHISMS: RELATIONSHIP TO OUTCOME FROM SEVERE SEPSIS AND SEPTIC SHOCK: 22 by Gordon, A. C., Aganna, E., Cheung, L., Peters, C. J., Piper, R. D., Mirakian, R. M., McDermott, M. F., Hitman, G. A., Hinds, C. J.

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Pancreatitis in fibrocalculous pancreatic diabetes mellitus is not associated with common mutations in the trypsinogen gene by Hassan, Zahid, Mohan, Viswanathan, McDermott, Michael F., Ali, Liaquat, Ogunkolade, William B., Aganna, Ebun, Cassell, Paul G., Deepa, Raj, Azad Khan, A. K., Hitman, Graham A.

“…Background A distinct type of pancreatitis associated with diabetes, termed fibrocalculous pancreatic diabetes (FCPD), has been reported in tropical developing…”
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Relationship between metalloproteinase9 tissue inhibitor of metalloproteinase-1 and vitamin D status: its relevance to ischaemic heart disease in asians by Timms, P.M., Mannan, N., Hitman, G.A., Aganna, E., Noonan, K., Mills, P.M., Syndercombe-Court, D., Patet, B., Price, C.P., Boucher, B.J.

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Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis by Aganna, Ebun, Martinon, Fabio, Hawkins, Philip N., Ross, John B., Swan, Daniel C., Booth, David R., Lachmann, Helen J., Gaudet, Roxanne, Woo, Patricia, Feighery, Conleth, Cotter, Finbarr E., Thome, Margot, Hitman, Graham A., Tschopp, Jürg, McDermott, Michael F.

“…Objective Familial cold urticaria (FCU) and Muckle‐Wells syndrome (MWS) are dominantly inherited autoinflammatory disorders that cause rashes, fever,…”
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Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study by Chowdhury, Z Md, McDermott, M F, Davey, S, Hassan, Z, Sinnott, P J, Hemmatpour, S K, Sherwin, S, Ali, L, Aganna, E, Allotey, R A, North, B V, Cassell, P G, Azad Khan, A K, Hitman, G A

“…Fibrocalculous pancreatic diabetes (FCPD) is an uncommon cause of diabetes, seen mainly in developing countries. A family-based study was carried out in 67…”
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