Search Results - "Agadjanyan, M.G"
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Active immunization with tau epitope in a mouse model of tauopathy induced strong antibody response together with improvement in short memory and pSer396-tau pathology
Published in Neurobiology of disease (01-02-2020)“…Abnormal tau hyperphosphorylation and its aggregation into neurofibrillary tangles are a hallmark of tauopathies, neurodegenerative disorders that include…”
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Inflammatory changes parallel the early stages of Alzheimer disease
Published in Neurobiology of aging (01-12-2007)“…Abstract Alzheimer disease (AD) is the most prominent cause of dementia in the elderly. To determine changes in the AD brain that may mediate the transition…”
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A fresh perspective from immunologists and vaccine researchers: Active vaccination strategies to prevent and reverse Alzheimer's disease
Published in Alzheimer's & dementia (01-10-2015)“…Abstract Traditional vaccination against infectious diseases relies on generation of cellular and humoral immune responses that act to protect the host from…”
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DNA prime-protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice
Published in Gene therapy (01-02-2010)“…Recently, we reported that a DNA vaccine, composed of three copies of a self B cell epitope of amyloid-β (Aβ 42 ) and the foreign T-cell epitope, Pan DR…”
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