Search Results - "Afshar, Saeid"
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1
Investigating the role of peptides in effective therapies against cancer
Published in Cancer cell international (27-03-2022)“…Early diagnosis and effective treatment of cancer are challenging. To diagnose and treat cancer effectively and to overcome these challenges, fundamental…”
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2
Deciphering the role of miR-71 and let-7 in the fertility of cystic echinococcosis cysts: a preliminary assessment
Published in Parasitology research (1987) (01-12-2022)“…Cystic echinococcosis (CE) is a neglected helminthic zoonosis in many parts of the world. Some CE cysts in the intermediate host are non-fertile. Considering…”
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Using machine learning approach for screening metastatic biomarkers in colorectal cancer and predictive modeling with experimental validation
Published in Scientific reports (08-11-2023)“…Colorectal cancer (CRC) liver metastasis accounts for the majority of fatalities associated with CRC. Early detection of metastasis is crucial for improving…”
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4
Novel biomarkers for neoplastic progression from ulcerative colitis to colorectal cancer: a systems biology approach
Published in Scientific reports (28-02-2023)“…In recent studies, the void of evaluation and in-depth understanding of unknown clinically relevant potential molecular biomarkers involved in colorectal…”
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5
Enhancing autophagy in Alzheimer's disease through drug repositioning
Published in Pharmacology & therapeutics (Oxford) (01-09-2022)“…Alzheimer's disease (AD) is one of the biggest human health threats due to increases in aging of the global population. Unfortunately, drugs for treating AD…”
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Assessment of lncRNA DANCR, miR-145-5p and NRAS axis as biomarkers for the diagnosis of colorectal cancer
Published in Molecular biology reports (01-04-2021)“…Recent evidence reveals that miRNA sponges neutralize miRNAs activity by binding to miRNAs and sequester them from their relevant targets to regulate…”
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Introducing novel key genes and transcription factors associated with rectal cancer response to chemoradiation through co-expression network analysis
Published in Heliyon (01-08-2023)“…Preoperative radiochemotherapy is a promising therapeutic method for locally advanced rectal cancer patients. However, the response of colorectal cancer (CRC)…”
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8
Near-infrared 940-nm diode laser photobiomodulation of inflamed periodontal ligament stem cells
Published in Lasers in medical science (01-02-2022)“…Photobiomodulation (PBM) is an acceptable method of stimulating stem cells through its non-invasive absorption by the cell photoreceptors and the induction of…”
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Human exposure to low dose ionizing radiation affects miR-21 and miR-625 expression levels
Published in Molecular biology reports (01-02-2022)“…Background Recently exposure to ionizing radiation driven by artificial radiation sources such as Medical X-rays and Nuclear medicine has increased hastily…”
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10
Identification of gene profiles related to the development of oral cancer using a deep learning technique
Published in BMC medical genomics (27-02-2023)“…Oral cancer (OC) is a debilitating disease that can affect the quality of life of these patients adversely. Oral premalignant lesion patients have a high risk…”
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Psoriasis Associated Hub Genes Revealed by Weighted Gene Co-Expression Network Analysis
Published in Cell journal (Yakhteh) (01-06-2023)“…Psoriasis, an immune-mediated disorder, is a multifactorial disease with unidentified cause(s). This study aimed to discover possible biomarkers of this…”
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A Randomized, Controlled, Parallel-Group, Trial on the Effects of Melatonin on Fatigue Associated with Breast Cancer and Its Adjuvant Treatments
Published in Integrative cancer therapies (2021)“…Objective: Fatigue associated with malignant conditions and their treatments is a disabling condition. This trial assessed the anti-fatigue effects of…”
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Assessment of Association between miR-146a Polymorphisms and Expression of miR-146a, TRAF-6, and IRAK-1 Genes in Patients with Brucellosis
Published in Molecular biology reports (01-03-2022)“…Background Brucellosis is a major zoonosis all over the world. MicroRNAs are significant gene expression regulators and could be involved during the infections…”
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14
Association between risk of brucellosis and genetic variations in MicroRNA-146a
Published in BMC infectious diseases (16-10-2021)“…Single nucleotide polymorphisms (SNPs) are the most common types of DNA changes in the human genome that leading to phenotypic differences in humans. MicroRNAs…”
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15
Identification of Prognostic Biomarkers for Breast Cancer Metastasis Using Penalized Additive Hazards Regression Model
Published in Cancer informatics (01-01-2023)“…Background: Breast cancer (BC) has been reported as one of the most common cancers diagnosed in females throughout the world. Survival rate of BC patients is…”
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Involvement of miR-155/FOXO3a and miR-222/PTEN in acquired radioresistance of colorectal cancer cell line
Published in Japanese journal of radiology (01-11-2017)“…Purpose Finding a novel biomarker for determining the radiosensitivity of colorectal cancer (CRC) is critical. The aim of this study is to evaluate the role of…”
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Cross-Resistance of Acquired Radioresistant Colorectal Cancer Cell Line to gefitinib and regorafenib
Published in Iranian journal of medical sciences (01-01-2020)“…Usually, chemoradiotherapy can be used for the treatment of locally advanced colorectal cancer (CRC) before surgery. On the other hand, some studies have shown…”
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MiR-15b and let-7a as Non-invasive Diagnostic Biomarkers of Alzheimer’s Disease Using an Artificial Neural Network
Published in Avicenna journal of medical biochemistry (29-12-2023)“…Background: Gaining insight into the underlying molecular mechanisms of Alzheimer’s disease (AD) is crucial. Objectives: This study aimed to employ a systems…”
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Identifying Key Genes and Approved Medications Associated with Major Depressive Disorder Using Network Analysis and Systems Biology
Published in Iranian journal of psychiatry (29-09-2024)“…Objective: Major depressive disorder (MDD) stands as one of the serious psychiatric conditions that detrimentally affect patients' quality of life and leads to…”
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In Silico and In Vitro Evaluation of Selected Herbal Compounds as Robust HER-2 Inhibitors for Effective Treatment of Breast Cancer
Published in Research journal of pharmacognosy (01-07-2023)“…Background and objectives: Breast cancer is the most frequently reported malignancy in women worldwide and is a heterogeneous disease. Due to different levels…”
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