Search Results - "Afonina, Irina A"

The Role of Cyclooxygenase 2 in Ulcerative Colitis-Associated Neoplasia by Agoff, S. Nicholas, Brentnall, Teresa A., Crispin, David A., Taylor, Shari L., Raaka, Stuart, Haggitt, Rodger C., Reed, Michael W., Afonina, Irina A., Rabinovitch, Peter S., Stevens, Allyn C., Feng, Ziding, Bronner, Mary P.

“…Cyclooxygenase 2 (COX-2) overexpression has been described in sporadic colonic neoplasia, but its role in ulcerative colitis (UC) neoplastic progression…”
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3'-minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures by Kutyavin, I V, Afonina, I A, Mills, A, Gorn, V V, Lukhtanov, E A, Belousov, E S, Singer, M J, Walburger, D K, Lokhov, S G, Gall, A A, Dempcy, R, Reed, M W, Meyer, R B, Hedgpeth, J

“…DNA probes with conjugated minor groove binder (MGB) groups form extremely stable duplexes with single-stranded DNA targets, allowing shorter probes to be used…”
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Single nucleotide polymorphism genotyping by two colour melting curve analysis using the MGB Eclipse Probe System in challenging sequence environment by Belousov, Yevgeniy S, Welch, Robert A, Sanders, Silvia, Mills, Alan, Kulchenko, Alena, Dempcy, Robert, Afonina, Irina A, Walburger, David K, Glaser, Cynthia L, Yadavalli, Sunita, Vermeulen, Nicolaas M J, Mahoney, Walt

“…Probe and primer design for single nucleotide polymorphism (SNP) detection can be very challenging for A-T DNA-rich targets, requiring long sequences with…”
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Reduced aggregation and improved specificity of G‐rich oligodeoxyribonucleotides containing pyrazolo[3,4‐d]pyrimidine guanine bases by Kutyavin, Igor V., Lokhov, Sergey G., Afonina, Irina A., Dempcy, Robert, Gall, Alexander A., Gorn, Vladimir V., Lukhtanov, Eugene, Metcalf, Mark, Mills, Alan, Reed, Michael W., Sanders, Sylvia, Shishkina, Irina, Vermeulen, Nicolaas M. J.

“…Guanine (G)‐rich oligodeoxyribonucleotides (ODNs) can form undesired complexes by self association through non‐Watson–Crick interactions. These aggregates can…”
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3'-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures by Kutyavin, I. V.

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Improved biplex quantitative real-time polymerase chain reaction with modified primers for gene expression analysis by Afonina, Irina A, Mills, Alan, Sanders, Silvia, Kulchenko, Alena, Dempcy, Robert, Lokhov, Sergey, Vermeulen, Nicolaas M J, Mahoney, Walt

“…Stabilizing modified bases incorporated in primers allows the reduction of housekeeping gene primer concentration not possible with regular primers without…”
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Triplex targeting of a native gene in permeabilized intact cells: Covalent modification of the gene for the chemokine receptor CCR5 by Belousov, Evgeniy S., Afonina, Irina A., Kutyavin, Igor V., Gall, Alexander A., Reed, Michael W., Gamper, Howard B., Wydro, Robert M., Meyer, Rich B.

“…A 12 nucleotide oligodeoxyribopurine tract in the gene for the chemokine receptor CCR5 has been targeted and covalently modified in intact cells by a 12mer…”
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Reduced aggregation and improved specificity of G-rich oligodeoxyribonucleotides containing pyrazolo3,4-dpyrimidine guanine bases by Kutyavin, Igor V, Lokhov, Sergey G, Afonina, Irina A, Dempcy, Robert, Gall, Alexander A, Gorn, Vladimir V, Lukhtanov, Eugene, Metcalf, Mark, Mills, Alan, Reed, Michael W, Sanders, Sylvia, Shishkina, Irina, Vermeulen, Nicolaas M J

“…Guanine (G)-rich oligodeoxyribonucleotides (ODNs) can form undesired complexes by self association through non-Watson-Crick interactions. These aggregates can…”
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Sequence-specific targeting and covalent modification of human genomic DNA by Belousov, Evgeniy S., Afonina, Irina A., Podyminogin, Mikhail A., Gamper, Howard B., Reed, Michael W., Wydro, Robert M., Meyer, Rich B.

“…We compare two techniques which enable selective, nucleotide-specific covalent modification of human genomic DNA, as assayed by quantitative ligationmediated…”
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