Search Results - "Affabris, Elisabetta"

SARS-CoV-2 Evasion of the Interferon System: Can We Restore Its Effectiveness? by Sacchi, Alessandra, Giannessi, Flavia, Sabatini, Andrea, Percario, Zulema Antonia, Affabris, Elisabetta

“…Type I and III Interferons (IFNs) are the first lines of defense in microbial infections. They critically block early animal virus infection, replication,…”
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The Role of Extracellular Vesicles as Allies of HIV, HCV and SARS Viruses by Giannessi, Flavia, Aiello, Alessandra, Franchi, Francesca, Percario, Zulema Antonia, Affabris, Elisabetta

“…Extracellular vesicles (EVs) are lipid bilayer-enclosed entities containing proteins and nucleic acids that mediate intercellular communication, in both…”
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Thyroid Hormones Interaction With Immune Response, Inflammation and Non-thyroidal Illness Syndrome by De Luca, Roberto, Davis, Paul J, Lin, Hung-Yun, Gionfra, Fabio, Percario, Zulema A, Affabris, Elisabetta, Pedersen, Jens Z, Marchese, Cinzia, Trivedi, Pankaj, Anastasiadou, Eleni, Negro, Roberto, Incerpi, Sandra

“…The interdependence between thyroid hormones (THs), namely, thyroxine and triiodothyronine, and immune system is nowadays well-recognized, although not yet…”
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Nongenomic effects of thyroid hormones on the immune system cells: New targets, old players by De Vito, Paolo, Balducci, Valentina, Leone, Stefano, Percario, Zulema, Mangino, Giorgio, Davis, Paul J., Davis, Faith B., Affabris, Elisabetta, Luly, Paolo, Pedersen, Jens Z., Incerpi, Sandra

“…► l-Thyroxine increases ROS production in THP-1 monocytes, through interaction with αvβ3 integrin. ► ROS production by thyroid hormones may induce cell…”
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Virus-Induced Tumorigenesis and IFN System by Iuliano, Marco, Mangino, Giorgio, Chiantore, Maria Vincenza, Di Bonito, Paola, Rosa, Paolo, Affabris, Elisabetta, Romeo, Giovanna

“…Oncogenic viruses favor the development of tumors in mammals by persistent infection and specific cellular pathways modifications by deregulating cell…”
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HIV-1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line by Aiello, Alessandra, Giannessi, Flavia, Percario, Zulema Antonia, Fecchi, Katia, Arenaccio, Claudia, Leone, Stefano, Carollo, Maria, D'Aversa, Elisabetta, Chaperot, Laurence, Gambari, Roberto, Sargiacomo, Massimo, Affabris, Elisabetta

“…Plasmacytoid dendritic cells (pDCs) are a unique dendritic cell subset specialized in type I interferon production, whose role in Human Immunodeficiency Virus…”
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Macrophages treated with interferons induce different responses in lymphocytes via extracellular vesicles by Giannessi, Flavia, Percario, Zulema, Lombardi, Valentina, Sabatini, Andrea, Sacchi, Alessandra, Lisi, Veronica, Battistini, Luca, Borsellino, Giovanna, Affabris, Elisabetta, Angelini, Daniela F.

“…Limited information exists regarding the impact of interferons (IFNs) on the information carried by extracellular vesicles (EVs). This study aimed at…”
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Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles by Incerpi, Sandra, Gionfra, Fabio, De Luca, Roberto, Candelotti, Elena, De Vito, Paolo, Percario, Zulema A., Leone, Stefano, Gnocchi, Davide, Rossi, Miriam, Caruso, Francesco, Scapin, Sergio, Davis, Paul J., Lin, Hung-Yun, Affabris, Elisabetta, Pedersen, Jens Z.

“…Thyroid hormones, T 3 (triiodothyronine) and T 4 (thyroxine), induce a variety of long-term effects on important physiological functions, ranging from…”
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Role of the microenvironment in tumourigenesis: focus on virus-induced tumors by Chiantore, Maria Vincenza, Mangino, Giorgio, Zangrillo, Maria Simona, Iuliano, Marco, Affabris, Elisabetta, Fiorucci, Gianna, Romeo, Giovanna

“…Tumor microenvironment can differ considerably in various types of tumors in terms of cellular and cytokine networks and molecular drivers. The well known link…”
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In vivo antitumor effect of an intracellular single‐chain antibody fragment against the E7 oncoprotein of human papillomavirus 16 by Accardi, Luisa, Paolini, Francesca, Mandarino, Angela, Percario, Zulema, Bonito, Paola, Carlo, Valentina, Affabris, Elisabetta, Giorgi, Colomba, Amici, Carla, Venuti, Aldo

“…Human papillomavirus (HPV)‐associated tumors still represent an urgent problem of public health in spite of the efficacy of the prophylactic HPV vaccines…”
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HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity by Mangino, Giorgio, Famiglietti, Marylinda, Capone, Caterina, Veroni, Caterina, Percario, Zulema Antonia, Leone, Stefano, Fiorucci, Gianna, Lülf, Sebastian, Romeo, Giovanna, Agresti, Cristina, Persichini, Tiziana, Geyer, Matthias, Affabris, Elisabetta

“…The potential role of the human immunodeficiency virus-1 (HIV-1) accessory protein Nef in the pathogenesis of neuroAIDS is still poorly understood. Nef is a…”
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HMGB1 and cord blood: its role as immuno-adjuvant factor in innate immunity by Ciucci, Alessandra, Gabriele, Ida, Percario, Zulema A, Affabris, Elisabetta, Colizzi, Vittorio, Mancino, Giorgio

“…In newborn the innate immune system provides essential protection during primary infections before the generation of an appropriate adaptive immune response…”
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Interferon-β induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activity by Chiantore, Maria V, Vannucchi, Serena, Accardi, Rosita, Tommasino, Massimo, Percario, Zulema A, Vaccari, Gabriele, Affabris, Elisabetta, Fiorucci, Gianna, Romeo, Giovanna

“…Interferon (IFN)-β inhibits cell proliferation and affects cell cycle in keratinocytes transformed by both mucosal high risk Human Papilloma Virus (HPV) and…”
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Staphylococcus aureus Esx Factors Control Human Dendritic Cell Functions Conditioning Th1/Th17 Response by Cruciani, Melania, Etna, Marilena P, Camilli, Romina, Giacomini, Elena, Percario, Zulema A, Severa, Martina, Sandini, Silvia, Rizzo, Fabiana, Brandi, Valentina, Balsamo, Giuliana, Polticelli, Fabio, Affabris, Elisabetta, Pantosti, Annalisa, Bagnoli, Fabio, Coccia, Eliana M

“…The opportunistic pathogen ( ) is a major cause of nosocomial- and community-acquired infections. In addition, many antibiotic-resistant strains are emerging…”
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HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2 by Mangino, Giorgio, Percario, Zulema A, Fiorucci, Gianna, Vaccari, Gabriele, Acconcia, Filippo, Chiarabelli, Cristiano, Leone, Stefano, Noto, Alessia, Horenkamp, Florian A, Manrique, Santiago, Romeo, Giovanna, Polticelli, Fabio, Geyer, Matthias, Affabris, Elisabetta

“…HIV-1 Nef is a virulence factor that plays multiple roles during HIV replication. Recently, it has been described that Nef intersects the CD40 signalling in…”
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Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3 by Candelotti, Elena, De Luca, Roberto, Megna, Roberto, Maiolo, Mariangela, De Vito, Paolo, Gionfra, Fabio, Percario, Zulema Antonia, Borgatti, Monica, Gambari, Roberto, Davis, Paul J, Lin, Hung-Yun, Polticelli, Fabio, Persichini, Tiziana, Colasanti, Marco, Affabris, Elisabetta, Pedersen, Jens Z, Incerpi, Sandra

“…Interaction between thyroid hormones and the immune system is reported in the literature. Thyroid hormones, thyroxine, T , but also T , act non-genomically…”
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In Vitro Treatment of Human Monocytes/Macrophages with Myristoylated Recombinant Nef of Human Immunodeficiency Virus Type 1 Leads to the Activation of Mitogen-Activated Protein Kinases, IκB Kinases, and Interferon Regulatory Factor 3 and to the Release of Beta Interferon by Mangino, Giorgio, Percario, Zulema A., Fiorucci, Gianna, Vaccari, Gabriele, Manrique, Santiago, Romeo, Giovanna, Federico, Maurizio, Geyer, Matthias, Affabris, Elisabetta

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors by Federico, Maurizio, Percario, Zulema, Olivetta, Eleonora, Fiorucci, Gianna, Muratori, Claudia, Micheli, Alessandro, Romeo, Giovanna, Affabris, Elisabetta

“…Monocytes/macrophages play a predominant role in the immunologic network by secreting and reacting to a wide range of soluble factors. Human immunodeficiency…”
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Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell endocytotic machinery by Percario, Zulema, Olivetta, Eleonora, Fiorucci, Gianna, Mangino, Giorgio, Peretti, Silvia, Romeo, Giovanna, Affabris, Elisabetta, Federico, Maurizio

“…Increasing evidence indicates that the expression of the human immunodeficiency virus‐1 (HIV‐1) Nef protein significantly influences the activation state of…”
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Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism by Arenaccio, Claudia, Chiozzini, Chiara, Columba-Cabezas, Sandra, Manfredi, Francesco, Affabris, Elisabetta, Baur, Andreas, Federico, Maurizio

“…Resting CD4+ T lymphocytes resist human immunodeficiency virus (HIV) infection. Here, we provide evidence that exosomes from HIV-1-infected cells render…”
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