Search Results - "Afentakis, Maria"

Assessment of Molecular Relapse Detection in Early-Stage Breast Cancer by Garcia-Murillas, Isaac, Chopra, Neha, Comino-Méndez, Iñaki, Beaney, Matthew, Tovey, Holly, Cutts, Rosalind J, Swift, Claire, Kriplani, Divya, Afentakis, Maria, Hrebien, Sarah, Walsh-Crestani, Giselle, Barry, Peter, Johnston, Stephen R D, Ring, Alistair, Bliss, Judith, Russell, Simon, Evans, Abigail, Skene, Anthony, Wheatley, Duncan, Dowsett, Mitch, Smith, Ian E, Turner, Nicholas C

“…Current treatment cures most cases of early-stage, primary breast cancer. However, better techniques are required to identify which patients are at risk of…”
Get more information

Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors by Leal, Mariana Ferreira, Haynes, Ben P, Schuster, Eugene, Yeo, Belinda, Afentakis, Maria, Zabaglo, Lila, Martins, Vera, Buus, Richard, Dodson, Andrew, Cheang, Maggie C U, Smith, Ian E, Martin, Lesley-Ann, Dowsett, Mitch

“…To investigate the presence of mutations in primary estrogen-receptor-positive (ER ) breast cancer treated with extended (>4 weeks) neoadjuvant (presurgical)…”
Get full text

Abstract 3608: Molecular fingerprint sequencing for minimal residual disease detection in breast cancer by Comino-Mendez, Iñaki, Cutts, Ros, García-Murillas, Isaac, Chopra, Neha, Afentakis, Maria, Evans, Abigail, Wheatley, Duncan, Skene, Anthony, Russell, Simon, Varughese, Mohini, Dowsett, Mitch, Smith, Ian E., Turner, Nick

“…Introduction: The substantial majority of breast cancers present with early-stage disease, although micro-metastatic disease may be established at the time of…”
Get full text

Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas by López-Knowles, Elena, Gao, Qiong, Cheang, Maggie Chon U, Morden, James, Parker, Joel, Martin, Lesley-Ann, Pinhel, Isabel, McNeill, Fiona, Hills, Margaret, Detre, Simone, Afentakis, Maria, Zabaglo, Lila, Dodson, Andrew, Skene, Anthony, Holcombe, Chris, Robertson, John, Smith, Ian, Bliss, Judith M, Dowsett, Mitch

“…Gene expression is widely used for the characterisation of breast cancers. Variability due to tissue heterogeneity or measurement error or systematic change…”
Get full text

Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: a TransATAC study by Afentakis, Maria, Dowsett, Mitch, Sestak, Ivana, Salter, Janine, Howell, Tony, Buzdar, Aman, Forbes, John, Cuzick, Jack

“…BAG1 is a multifunctional anti-apoptotic protein located on chromosome 9q12, which binds to Bcl-2. BAG1 is present as a separate module in the GHI-RS 21-gene…”
Get full text

Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: a TransATAC study by Afentakis, Maria, Dowsett, Mitch, Sestak, Ivana, Salter, Janine, Howell, Tony, Buzdar, Aman, Forbes, John, Cuzick, Jack

“…BAG1 is a multifunctional anti-apoptotic protein located on chromosome 9q12, which binds to Bcl-2. BAG1 is present as a separate module in the GHI-RS 21-gene…”
Get full text

Menstrual cycle associated changes in hormone-related gene expression in oestrogen receptor positive breast cancer by Haynes, Ben P., Ginsburg, Ophira, Gao, Qiong, Folkerd, Elizabeth, Afentakis, Maria, Buus, Richard, Quang, Le Hong, Thi Han, Pham, Khoa, Pham Hong, Dinh, Nguyen Van, To, Ta Van, Clemons, Mark, Holcombe, Chris, Osborne, Caroline, Evans, Abigail, Skene, Anthony, Sibbering, Mark, Rogers, Clare, Laws, Siobhan, Noor, Lubna, Smith, Ian E., Dowsett, Mitch

“…The major changes in hormone levels that occur through the menstrual cycle have been postulated to affect the expression of hormone-regulated and…”
Get full text

Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy by Haynes, Ben P., Ginsburg, Ophira, Gao, Qiong, Folkerd, Elizabeth, Afentakis, Maria, Quang, Le Hong, Han, Pham Thi, Khoa, Pham Hong, Dinh, Nguyen Van, To, Ta Van, Clemons, Mark, Smith, Ian E., Dowsett, Mitch

“…For premenopausal women with primary ER + breast cancer, oophorectomy (OvX) is an evidence-based cost-effective option and is standard treatment in many…”
Get full text