Search Results - "Aessopos, Athanassios"
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Cardiac magnetic resonance imaging R2 assessments and analysis of historical parameters in patients with transfusion-dependent thalassemia
Published in Haematologica (Roma) (01-01-2007)“…* From the First Department of Medicine, University of Athens, Laiko General Hospital, Aghio Thoma 17, Athens Greece; ° The Thalassemia Unit, "Aghia Sophia"…”
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Effect of deferiprone or deferoxamine on right ventricular function in thalassemia major patients with myocardial iron overload
Published in Journal of cardiovascular magnetic resonance (06-07-2011)“…Thalassaemia major (TM) patients need regular blood transfusions that lead to accumulation of iron and death from heart failure. Deferiprone has been reported…”
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Intensive chelation therapy in β-thalassemia and possible adverse cardiac effects of desferrioxamine
Published in International journal of hematology (01-10-2007)“…Combination chelation therapy with desferrioxamine and deferiprone has recently been suggested as a more effective tissue iron-chelating treatment for…”
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4
Comparison of echocardiographic (US) volumetry with cardiac magnetic resonance (CMR) imaging in transfusion dependent thalassemia major (TM)
Published in Cardiovascular ultrasound (14-07-2007)“…Despite advances in survival in patients with thalassemia major (TM) the most common cause of death is cardiac disease. Regular cardiac follow-up is imperative…”
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5
Predictive echo-Doppler indices of left ventricular impairment in B-thalassemic patients
Published in Annals of hematology (01-06-2007)“…Early detection of cardiac-function impairment by echo-Doppler indices can assist in preventing further cardiac damage by modifying disease progression and…”
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Prevention of Cardiomyopathy in Transfusion-Dependent Homozygous Thalassaemia Today and the Role of Cardiac Magnetic Resonance Imaging
Published in Advances in hematology (2009)“…Transfusion and iron chelation therapy revolutionised survival and reduced morbidity in patients with transfusion-dependent beta thalassaemia major. Despite…”
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7
The heart in transfusion dependent homozygous thalassaemia today - prediction, prevention and management
Published in European journal of haematology (01-02-2008)“…Cardiac disease remains the major cause of death in thalassaemia major. This review deals with the mechanisms involved in heart failure development, the…”
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Thalassemia intermedia today: should patients regularly receive transfusions?
Published in Transfusion (Philadelphia, Pa.) (01-05-2007)“…BACKGROUND: β‐Thalassemia is an inherited hemoglobin disorder characterized by reduced synthesis of β‐globin chain. The severity of clinical course…”
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Randomized controlled trial of deferiprone or deferoxamine in beta-thalassemia major patients with asymptomatic myocardial siderosis
Published in Blood (01-05-2006)“…Most deaths in beta-thalassemia major result from cardiac complications due to iron overload. Differential effects on myocardial siderosis may exist between…”
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10
Liver iron concentration and fibrosis in a cohort of transfusion-dependent patients on long-term desferrioxamine therapy
Published in The hematology journal : the official journal of the European Haematology Association (2005)“…Secondary iron overload is associated with significant mortality and morbidity. Although new, less invasive techniques are becoming available, the most…”
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11
Acute brucellosis: presentation, diagnosis, and treatment of 144 cases
Published in International journal of infectious diseases (01-01-2007)“…Summary Objectives Brucellosis, whether in an endemic region or not, remains a diagnostic puzzle due to occasional misleading unusual presentations and…”
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12
Overexpression of survivin levels in circulation and tissue samples of lung cancer patients
Published in Anticancer research (01-08-2013)“…Survivin, an apoptosis inhibitor protein, has multiple functions that favor cancer cell survival. We sought to determine survivin levels in blood samples and…”
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13
Extramedullary Hematopoiesis-Related Pleural Effusion: The Case of β-Thalassemia
Published in The Annals of thoracic surgery (01-06-2006)“…Thalassemia intermedia has a later clinical onset and a milder anemia than thalassemia major, characterized by high output state, left ventricle remodeling,…”
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14
Intensive Chelation Therapy in β-Thalassemia and Possible Adverse Cardiac Effects of Desferrioxamine
Published in International journal of hematology (01-10-2007)Get full text
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15
Intervertebral disc calcification in thalassemia intermedia
Published in European journal of haematology (01-02-2008)“…Objectives: Intervertebral disc calcification, an age‐related phenomenon of variable clinical significance is described in hemochromatosis. As β‐thalassemia…”
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Congestive Heart Failure and Treatment in Thalassemia Major
Published in Hemoglobin (2008)“…The homozygous β-thalassemias are a group of genetically inherited hemoglobin (Hb) disorders characterized by dyserythropoietic anemia. According to the degree…”
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Correlation of echocardiography parameters with cardiac magnetic resonance imaging in transfusion-dependent thalassaemia major
Published in European journal of haematology (01-01-2007)“…Background and objective: Heart iron load (cardiac Fe) can be indirectly quantified by cardiac magnetic resonance (CMR) T2*. CMR accessibility is limited,…”
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Effects of Combined Deferiprone and Deferoxamine Chelation Therapy on Iron Load Indices in β-Thalassemia
Published in Hemoglobin (2008)“…The benefits of combined deferoxamine (DFO) and deferiprone (L1) chelation therapy, focusing on reducing myocardial iron loading, have been widely reported…”
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Does Heterozygous β-Thalassemia Confer a Protection against Coronary Artery Disease?
Published in Annals of the New York Academy of Sciences (01-01-2005)“…: Six hundred and thirty‐eight patients who presented with clinical symptoms and/or electrocardiographic findings suggestive of stable angina pectoris were…”
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Lack of correlation between iron overload cardiac dysfunction and needle liver biopsy iron concentration
Published in Haematologica (Roma) (01-05-2005)“…In 58 patients with transfusion dependent anemia, we compared cardiac function, as assessed by gated pooled cardiac scan at rest and during exercise stress,…”
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