Search Results - "Aerts, Jordan T."
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Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry
Published in Nature protocols (01-04-2013)“…Single-cell mass spectrometry (MS) empowers metabolomic investigations by decreasing analytical dimensions to the size of individual cells and subcellular…”
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Patch Clamp Electrophysiology and Capillary Electrophoresis–Mass Spectrometry Metabolomics for Single Cell Characterization
Published in Analytical chemistry (Washington) (18-03-2014)“…The visual selection of specific cells within an ex vivo brain slice, combined with whole-cell patch clamp recording and capillary electrophoresis (CE)–mass…”
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Zero-Degree Celsius Capillary Electrophoresis Electrospray Ionization for Hydrogen Exchange Mass Spectrometry
Published in Analytical chemistry (Washington) (17-01-2023)“…Currently, fast liquid chromatographic separations at low temperatures are exclusively used for the separation of peptides generated in hydrogen deuterium…”
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Electrochemically Etched Tapered-Tip Stainless-Steel Electrospray-Ionization Emitters for Capillary Electrophoresis–Mass Spectrometry
Published in Journal of proteome research (07-04-2023)“…We have used household consumables to facilitate electrochemical etching of stainless-steel hypodermic tubing to produce tapered-tip emitters suitable for…”
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Analysis of endogenous nucleotides by single cell capillary electrophoresis-mass spectrometry
Published in Analyst (London) (21-11-2014)“…Analytical technologies that enable investigations at the single cell level facilitate a range of studies; here a lab-fabricated capillary…”
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Enantioselective CE–MS analysis of ketamine metabolites in urine
Published in Electrophoresis (01-01-2023)“…The chiral drug ketamine has long‐lasting antidepressant effects with a fast onset and is also suitable to treat patients with therapy‐resistant depression…”
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Rapid Metabolic Profiling of 1 μL Crude Cerebrospinal Fluid by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Can Differentiate De Novo Parkinson’s Disease
Published in Analytical chemistry (Washington) (19-12-2023)“…Parkinson’s disease (PD) is a highly prevalent neurodegenerative disorder affecting the motor system. However, the correct diagnosis of PD and atypical…”
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MALDI-guided SIMS: Multiscale Imaging of Metabolites in Bacterial Biofilms
Published in Analytical chemistry (Washington) (16-09-2014)“…Mass spectrometry imaging (MSI) is a versatile tool for visualizing molecular distributions in complex biological specimens, but locating microscopic chemical…”
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Small-Volume Analysis of Cell―Cell Signaling Molecules in the Brain
Published in Neuropsychopharmacology (New York, N.Y.) (01-01-2014)“…Modern science is characterized by integration and synergy between research fields. Accordingly, as technological advances allow new and more ambitious quests…”
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Inquiry-based Learning of Proteomics and Metabolomics
Published in Journal of chemical education (13-02-2024)“…Given the rapid development of data-driven experimental procedures within the life sciences, it is important to equip students with proper skills and knowledge…”
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