Search Results - "Adwanikar, Hita"

Long-Term Effects of Traumatic Brain Injury on Anxiety-Like Behaviors in Mice: Behavioral and Neural Correlates by Popovitz, Juliana, Mysore, Shreesh P, Adwanikar, Hita

“…Traumatic brain injury (TBI) has been frequently linked to affective disorders such as anxiety and depression. However, much remains to be understood about the…”
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Non-Pain-Related CRF1 Activation in the Amygdala Facilitates Synaptic Transmission and Pain Responses by Ji, Guangchen, Fu, Yu, Adwanikar, Hita, Neugebauer, Volker

“…Background Corticotropin-releasing factor (CRF) plays an important role in affective states and disorders. CRF is not only a “stress hormone” but also a…”
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Facilitation of Synaptic Transmission and Pain Responses by CGRP in the Amygdala of Normal Rats by Han, Jeong S, Adwanikar, Hita, Li, Zhen, Ji, Guangchen, Neugebauer, Volker

“…Calcitonin gene-related peptide (CGRP) plays an important role in peripheral and central sensitization. CGRP also is a key molecule in the…”
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Techniques for Assessing Knee Joint Pain in Arthritis by Neugebauer, Volker, Han, Jeong S, Adwanikar, Hita, Fu, Yu, Ji, Guangchen

“…The assessment of pain is of critical importance for mechanistic studies as well as for the validation of drug targets. This review will focus on knee joint…”
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Matrix Metalloproteinases and Neurotrauma: Evolving Roles in Injury and Reparative Processes by Zhang, Haoqian, Adwanikar, Hita, Werb, Zena, Noble-Haeusslein, Linda J.

“…Matrix metalloproteinases (MMPs) are involved in a wide range of proteolytic events in fetal development and normal tissue remodeling as well as wound healing…”
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PKA and ERK, but not PKC, in the Amygdala Contribute to Pain-Related Synaptic Plasticity and Behavior by Fu, Yu, Han, Jeong, Ishola, Titilope, Scerbo, Michelle, Adwanikar, Hita, Ramsey, Cara, Neugebauer, Volker

“…The laterocapsular division of the central nucleus of the amygdala (CeLC) has emerged as an important site of pain-related plasticity and pain modulation…”
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Pain-Related Synaptic Plasticity in Spinal Dorsal Horn Neurons: Role of CGRP by Bird, Gary C, Han, Jeong S, Fu, Yu, Adwanikar, Hita, Willis, William D, Neugebauer, Volker

“…Background The synaptic and cellular mechanisms of pain-related central sensitization in the spinal cord are not fully understood yet. Calcitonin gene-related…”
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Age is a determinant of leukocyte infiltration and loss of cortical volume after traumatic brain injury by Claus, Catherine P, Tsuru-Aoyagi, Kyoko, Adwanikar, Hita, Walker, Breset, Manvelyan, Hovhannes, Whetstone, William, Noble-Haeusslein, Linda J

“…There is increasing evidence that the inflammatory response differs in the injured developing brain as compared to the adult brain. Here we compared cerebral…”
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Impaired Inflammatory Pain and Thermal Hyperalgesia in Mice Expressing Neuron-Specific Dominant Negative Mitogen Activated Protein Kinase Kinase (MEK) by Karim, Farzana, Hu, Hui-Juan, Adwanikar, Hita, Kaplan, David, Robert, W Gereau

“…Background Numerous studies have implicated spinal extracellular signal-regulated kinases (ERKs) as mediators of nociceptive plasticity. These studies have…”
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Neural Markers of Vulnerability to Anxiety Outcomes after Traumatic Brain Injury by Popovitz, Juliana, Mysore, Shreesh P, Adwanikar, Hita

“…Anxiety outcomes after traumatic brain injury (TBI) are complex, and the underlying neural mechanisms are poorly understood. Here, we developed a…”
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Models of Traumatic Cerebellar Injury by Potts, Matthew B., Adwanikar, Hita, Noble-Haeusslein, Linda J.

“…Traumatic brain injury (TBI) is a major cause of morbidity and mortality worldwide. Studies of human TBI demonstrate that the cerebellum is sometimes affected…”
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Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation by Adwanikar, Hita, Karim, Farzana, Gereau, Robert W.

“…Group I metabotropic glutamate receptors (mGluRs) and their downstream signaling pathways, which involve the extracellular signal-regulated kinases (ERKs),…”
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Spinal CGRP1 receptors contribute to supraspinally organized pain behavior and pain-related sensitization of amygdala neurons by Adwanikar, Hita, Ji, Guangchen, Li, Weidong, Doods, Henri, Willis, William D., Neugebauer, Volker

“…CGRP receptor activation has been implicated in peripheral and central sensitization. The role of spinal CGRP receptors in supraspinal pain processing and…”
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Modulation of Presynaptic Calcium Transients by Metabotropic Glutamate Receptor Activation: A Differential Role in Acute Depression of Synaptic Transmission and Long-Term Depression by Faas, Guido C, Adwanikar, Hita, Gereau, Robert W., IV, Saggau, Peter

“…Activation of group I metabotropic glutamate receptors (mGluRs) can induce acute depression of excitatory synaptic transmission and long-term depression (LTD)…”
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