Search Results - "Adwan, Lina"
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Epigenetics: A novel therapeutic approach for the treatment of Alzheimer's disease
Published in Pharmacology & therapeutics (Oxford) (01-07-2013)“…Alzheimer's disease (AD) is the most common type of dementia in the elderly. It is characterized by the deposition of two forms of aggregates within the brain,…”
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Short-term treatment with tolfenamic acid improves cognitive functions in Alzheimer's disease mice
Published in Neurobiology of aging (01-10-2013)“…Abstract Tolfenamic acid lowers the levels of the amyloid precursor protein (APP) and amyloid beta (Aβ) when administered to C57BL/6 mice by lowering their…”
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3
Alarmingly high prevalence of high-risk drug use among palestinian males: a cross-sectional study
Published in BMC psychiatry (26-09-2023)“…The unique socioeconomic context in Palestine, characterized by political and economic tensions, creates conditions that facilitate the spread of illicit drug…”
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Clinical outcomes of COVID-19 in hemodialysis patients
Published in Frontiers in medicine (13-11-2023)“…Background The coronavirus disease 2019 (COVID-19) is known for its effects on the respiratory system. Three years after the pandemic morbid and mortal…”
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Composition, Anticholinesterase and Antipedicular Activities of Satureja capitata L. Volatile Oil
Published in Open life sciences (28-02-2020)“…The emergence of resistance for antipedicular agents and the need of potent acetylcholinesterase (AChE) therapeutics for the treatment of a neurodegenerative…”
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Reduction of amyloid-β deposition and attenuation of memory deficits by tolfenamic acid
Published in Journal of Alzheimer's disease (01-01-2015)“…We have previously reported that tolfenamic acid treatment decreases the amyloidogenic proteins in C57BL/6 and in old hemizygous R1.40 transgenic mice via the…”
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Cellular and Organismal Toxicity of the Anti-Cancer Small Molecule, Tolfenamic Acid: a Pre-Clinical Evaluation
Published in Cellular physiology and biochemistry (01-01-2013)“…Background/Aims: The small molecule, Tolfenamic acid (TA) has shown anti-cancer activity in pre-clinical models and is currently in Phase I clinical trials at…”
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Israel’s spatial and a-spatial strategy of dispossessing the Jordan Valley’s Palestinian Inhabitants
Published in GeoJournal (22-04-2023)“…The Jordan Valley’s territorial extent is defined for this study as an elongated stretch of border area, located west of Jordan’s boundary with the West Bank,…”
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Tolfenamic acid reduces tau and CDK5 levels: implications for dementia and tauopathies
Published in Journal of neurochemistry (01-04-2015)“…Tau and its aggregates are linked to the pathology of Alzheimer's disease (AD) and other tauopathies and, therefore, are explored as therapeutic targets for…”
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Tolfenamic acid downregulates BACE1 and protects against lead-induced upregulation of Alzheimer's disease related biomarkers
Published in Neuropharmacology (01-04-2014)“…Environmental exposure to lead (Pb) early in life results in a latent upregulation of genes and products associated with Alzheimer's disease (AD), particularly…”
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P4‐231: A novel approach for lowering multiple targets in Alzheimer's disease
Published in Alzheimer's & dementia (01-07-2012)Get full text
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A novel approach for lowering multiple targets in Alzheimer's disease
Published in Alzheimer's & dementia (01-07-2012)Get full text
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Tolfenamic acid reduces tau and CDK 5 levels: implications for dementia and tauopathies
Published in Journal of neurochemistry (01-04-2015)“…Abstract Tau and its aggregates are linked to the pathology of Alzheimer's disease (AD) and other tauopathies and, therefore, are explored as therapeutic…”
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Variability of Chemical Compositions and Antimicrobial and Antioxidant Activities of Ruta chalepensis Leaf Essential Oils from Three Palestinian Regions
Published in BioMed research international (01-01-2017)“…Introduction. Interest in essential oils was recently revived with their popularity increasing in medicine, pharmacy, and aromatherapy. This study was…”
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Screening of Antioxidant and Antimicrobial Activity of Micromeria fruticosa serpyllifolia Volatile Oils: A Comparative Study of Plants Collected from Different Regions of West Bank, Palestine
Published in BioMed research international (2020)“…Background. The investigation of volatile oils used in traditional medicine is vital to enhance the quality of healthcare. This study is aimed at screening the…”
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Short-term treatment with tolfenamic acid improves cognitive functions in AD mice
Published in Neurobiology of aging (30-04-2013)“…Tolfenamic acid lowers the levels of the amyloid precursor protein (APP) and amyloid beta (Aβ) when administered to C57BL/6 mice by lowering their…”
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Chemical composition, anthelmintic, antibacterial and antioxidant effects of Thymus bovei essential oil
Published in BMC complementary and alternative medicine (26-10-2016)“…It has been recently recognized that oxidative stress, helminth and microbial infections are the cause of much illness found in the underdeveloped, developing…”
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Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice
Published in Journal of Alzheimer's disease (01-01-2009)“…Alzheimer's disease (AD) is characterized by plaques of amyloid-beta (Abeta) peptide, cleaved from amyloid-beta protein precursor (AbetaPP). Our hypothesis is…”
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Pharmacodynamic mechanisms of tolfenamic acid induced Sp1 degradation relative to Alzheimer's disease pathology
Published 01-01-2013“…Alzheimer's disease (AD) continues to disrupt the lives of millions of patients and caregivers around the world. The few drugs currently used for AD have…”
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