Search Results - "Advances in experimental medicine and biology"

Circular RNAs Act as miRNA Sponges by Panda, Amaresh Chandra

“…Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular RNAs, circular (circ)RNAs include a large family of noncoding…”
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Glucose Metabolism in Cancer: The Warburg Effect and Beyond by Bose, Sminu, Zhang, Cissy, Le, Anne

“…Otto Warburg observed a peculiar phenomenon in 1924, unknowingly laying the foundation for the field of cancer metabolism. While his contemporaries…”
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Epidemiology of skin cancer by Leiter, Ulrike, Eigentler, Thomas, Garbe, Claus

“…Melanoma and nonmelanoma skin cancer (NMSC) are now the most common types of cancer in white populations. Both tumor entities show an increasing incidence rate…”
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Regulation of Autophagy by mTOR Signaling Pathway by Wang, Ying, Zhang, Hongbing

“…Autophagy plays a crucial role in maintaining cellular homeostasis, and is closely related to the occurrence of variety of human diseases. It is known that…”
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The Role of Early Life Stress in HPA Axis and Anxiety by Juruena, Mario F, Eror, Filip, Cleare, Anthony J, Young, Allan H

“…Substantial evidence from various studies suggests a preeminent role for early adverse experiences in the development of psychopathology. The most recent…”
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Insulin Resistance, Obesity and Lipotoxicity by Yazıcı, Dilek, Sezer, Havva

“…Lipotoxicity , originally used to describe the destructive effects of excess fat accumulation on glucose metabolism, causes functional impairments in several…”
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The Role of NCOA4-Mediated Ferritinophagy in Ferroptosis by Santana-Codina, Naiara, Gikandi, Ajami, Mancias, Joseph D

“…Nuclear receptor coactivator 4 (NCOA4) is a selective cargo receptor that mediates the autophagic degradation of ferritin, the cytosolic iron storage complex,…”
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Immunotherapy in NSCLC: A Promising and Revolutionary Weapon by Rolfo, Christian, Caglevic, Christian, Santarpia, Mariacarmela, Araujo, Antonio, Giovannetti, Elisa, Gallardo, Carolina Diaz, Pauwels, Patrick, Mahave, Mauricio

“…Lung cancer is the leader malignancy worldwide accounting 1.5 millions of deaths every year. In the United States the 5 year-overall survival is less than 20%…”
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Regulation of Glucose Homeostasis by Glucocorticoids by Kuo, Taiyi, McQueen, Allison, Chen, Tzu-Chieh, Wang, Jen-Chywan

“…Glucocorticoids are steroid hormones that regulate multiple aspects of glucose homeostasis. Glucocorticoids promote gluconeogenesis in liver, whereas in…”
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Overview of Histone Modification by Zhang, Yanjun, Sun, Zhongxing, Jia, Junqi, Du, Tianjiao, Zhang, Nachuan, Tang, Yin, Fang, Yuan, Fang, Dong

“…Epigenetics is the epi-information beyond the DNA sequence that can be inherited from parents to offspring. From years of studies, people have found that…”
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NF-kB and Inflammatory Cytokine Signalling: Role in Skeletal Muscle Atrophy by Thoma, Anastasia, Lightfoot, Adam P

“…Atrophy is a classical hallmark of an array of disorders that affect skeletal muscle, ranging from inherited dystrophies, acquired inflammatory myopathies,…”
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Comorbid Anxiety and Depression: Clinical and Conceptual Consideration and Transdiagnostic Treatment by Choi, Kwan Woo, Kim, Yong-Ku, Jeon, Hong Jin

“…Although anxiety and depression have been considered as two distinct entities according to the diagnostic criteria, anxious depression (comorbid anxiety and…”
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Deep Learning in Medical Image Analysis by Chan, Heang-Ping, Samala, Ravi K, Hadjiiski, Lubomir M, Zhou, Chuan

“…Deep learning is the state-of-the-art machine learning approach. The success of deep learning in many pattern recognition applications has brought excitement…”
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Circular RNA and Alzheimer's Disease by Akhter, Rumana

“…Circular RNAs (circRNAs) represent a special group of noncoding single-stranded highly stable ribonucleic acid entities abundant in the eukaryotic…”
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The Definition and Prevalence of Obesity and Metabolic Syndrome by Engin, Atilla

“…Increase in prevalence of obesity has become a worldwide major health problem in adults, as well as among children and adolescents. Furthermore, total…”
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Neuron-Specific Enolase as a Biomarker: Biochemical and Clinical Aspects by Isgrò, Maria Antonietta, Bottoni, Patrizia, Scatena, Roberto

“…Neuron-specific enolase (NSE) is known to be a cell specific isoenzyme of the glycolytic enzyme enolase. In vertebrate organisms three isozymes of enolase,…”
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Amyloid-β and Tau at the Crossroads of Alzheimer's Disease by Gallardo, Gilbert, Holtzman, David M

“…Alzheimer's disease (AD) is the most common form of dementia characterized neuropathologically by senile plaques and neurofibrillary tangles (NFTs). Early…”
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MicroRNAs in human cancer by Farazi, Thalia A, Hoell, Jessica I, Morozov, Pavel, Tuschl, Thomas

“…Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20-23-nucleotide (nt) length that control gene expression in many cellular processes. These…”
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The prevalence of congenital anomalies in Europe by Dolk, Helen, Loane, Maria, Garne, Ester

“…EUROCAT (European Surveillance of Congenital Anomalies) is the network of population-based registers of congenital anomaly in Europe, with a common protocol…”
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Sonodynamic Therapy: Concept, Mechanism and Application to Cancer Treatment by McHale, Anthony P, Callan, John F, Nomikou, Nikolitsa, Fowley, Colin, Callan, Bridgeen

“…Sonodynamic therapy (SDT) represents an emerging approach that offers the possibility of non-invasively eradicating solid tumors in a site-directed manner. It…”
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