Search Results - "Advanced drug delivery reviews"

The role of lipid components in lipid nanoparticles for vaccines and gene therapy by Hald Albertsen, Camilla, Kulkarni, Jayesh A., Witzigmann, Dominik, Lind, Marianne, Petersson, Karsten, Simonsen, Jens B.

“…[Display omitted] Lipid nanoparticles (LNPs) play an important role in mRNA vaccines against COVID-19. In addition, many preclinical and clinical studies,…”
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Liposome composition in drug delivery design, synthesis, characterization, and clinical application by Large, Danielle E., Abdelmessih, Rudolf G., Fink, Elizabeth A., Auguste, Debra T.

“…[Display omitted] Liposomal drug delivery represents a highly adaptable therapeutic platform for treating a wide range of diseases. Natural and synthetic…”
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Extracellular vesicles as drug delivery systems: Why and how? by Elsharkasy, Omnia M., Nordin, Joel Z., Hagey, Daniel W., de Jong, Olivier G., Schiffelers, Raymond M., Andaloussi, Samir EL, Vader, Pieter

“…Over the past decades, a multitude of synthetic drug delivery systems has been developed and introduced to the market. However, applications of such systems…”
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Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications by Dadfar, Seyed Mohammadali, Roemhild, Karolin, Drude, Natascha I., von Stillfried, Saskia, Knüchel, Ruth, Kiessling, Fabian, Lammers, Twan

“…Many different iron oxide nanoparticles have been evaluated over the years, for a wide variety of biomedical applications. We here summarize the synthesis,…”
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Tumor targeting via EPR: Strategies to enhance patient responses by Golombek, Susanne K., May, Jan-Niklas, Theek, Benjamin, Appold, Lia, Drude, Natascha, Kiessling, Fabian, Lammers, Twan

“…The tumor accumulation of nanomedicines relies on the enhanced permeability and retention (EPR) effect. In the last 5–10 years, it has been increasingly…”
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Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers by Fang, Jun, Islam, Waliul, Maeda, Hiroshi

“…The enhanced permeability and retention (EPR) effect is a unique phenomenon of solid tumors that is related to their particular anatomical and…”
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Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine by Donahue, Nathan D., Acar, Handan, Wilhelm, Stefan

“…Nanoparticle-based therapeutics and diagnostics are commonly referred to as nanomedicine and may significantly impact the future of healthcare. However, the…”
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Self-assembled mRNA vaccines by Kim, Jeonghwan, Eygeris, Yulia, Gupta, Mohit, Sahay, Gaurav

“…mRNA vaccines have evolved from being a mere curiosity to emerging as COVID-19 vaccine front-runners. Recent advancements in the field of RNA technology,…”
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Therapeutic strategies for enhancing angiogenesis in wound healing by Veith, Austin P., Henderson, Kayla, Spencer, Adrianne, Sligar, Andrew D., Baker, Aaron B.

“…The enhancement of wound healing has been a goal of medical practitioners for thousands of years. The development of chronic, non-healing wounds is a…”
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Physical and mechanical properties of PLA, and their functions in widespread applications — A comprehensive review by Farah, Shady, Anderson, Daniel G., Langer, Robert

“…Poly(lactic acid) (PLA), so far, is the most extensively researched and utilized biodegradable aliphatic polyester in human history. Due to its merits, PLA is…”
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Hepatic stellate cells as key target in liver fibrosis by Higashi, Takaaki, Friedman, Scott L., Hoshida, Yujin

“…Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more than one million deaths annually via development of cirrhosis,…”
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To PEGylate or not to PEGylate: Immunological properties of nanomedicine’s most popular component, polyethylene glycol and its alternatives by Shi, Da, Beasock, Damian, Fessler, Adam, Szebeni, Janos, Ljubimova, Julia Y., Afonin, Kirill A., Dobrovolskaia, Marina A.

“…[Display omitted] Polyethylene glycol or PEG has a long history of use in medicine. Many conventional formulations utilize PEG as either an active ingredient…”
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COVID-19 vaccines: The status and perspectives in delivery points of view by Chung, Jee Young, Thone, Melissa N., Kwon, Young Jik

“…Due to the high prevalence and long incubation periods often without symptoms, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has infected…”
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Advanced drug delivery systems and artificial skin grafts for skin wound healing by Kim, Hye Sung, Sun, Xiaoyan, Lee, Jung-Hwan, Kim, Hae-Won, Fu, Xiaobing, Leong, Kam W.

“…Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require painstakingly long-term treatment with an immense financial burden to…”
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PEGylation as a strategy for improving nanoparticle-based drug and gene delivery by Suk, Jung Soo, Xu, Qingguo, Kim, Namho, Hanes, Justin, Ensign, Laura M.

“…Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a commonly used approach for improving the efficiency of drug and gene…”
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Liposomes: Advancements and innovation in the manufacturing process by Shah, Sanket, Dhawan, Vivek, Holm, René, Nagarsenker, Mangal S., Perrie, Yvonne

“…Liposomes are well recognised as effective drug delivery systems, with a range of products approved, including follow on generic products. Current…”
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Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals by Kozma, Gergely Tibor, Shimizu, Taro, Ishida, Tatsuhiro, Szebeni, Janos

“…Conjugation of polyethylene glycols (PEGs) to proteins or drug delivery nanosystems is a widely accepted method to increase the therapeutic index of complex…”
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In situ forming injectable hydrogels for drug delivery and wound repair by Dimatteo, Robert, Darling, Nicole J., Segura, Tatiana

“…Hydrogels have been utilized in regenerative applications for many decades because of their biocompatibility and similarity in structure to the native…”
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Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention by Butler, Lisa M., Perone, Ylenia, Dehairs, Jonas, Lupien, Leslie E., de Laat, Vincent, Talebi, Ali, Loda, Massimo, Kinlaw, William B., Swinnen, Johannes V.

“…With the advent of effective tools to study lipids, including mass spectrometry-based lipidomics, lipids are emerging as central players in cancer biology…”
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Recent advancements in liposome technology by Filipczak, Nina, Pan, Jiayi, Yalamarty, Satya Siva Kishan, Torchilin, Vladimir P.

“…The liposomes have continued to be well-recognized as an important nano-sized drug delivery system with attractive properties, such a characteristic bilayer…”
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