Search Results - "Adusumilli, Sneha"

Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation by Kuenze, Georg, Vanoye, Carlos G, Desai, Reshma R, Adusumilli, Sneha, Brewer, Kathryn R, Woods, Hope, McDonald, Eli F, Sanders, Charles R, George, Jr, Alfred L, Meiler, Jens

“…The function of the voltage-gated KCNQ1 potassium channel is regulated by co-assembly with KCNE auxiliary subunits. KCNQ1-KCNE1 channels generate the slow…”
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High-throughput evaluation of epilepsy-associated KCNQ2 variants reveals functional and pharmacological heterogeneity by Vanoye, Carlos G, Desai, Reshma R, Ji, Zhigang, Adusumilli, Sneha, Jairam, Nirvani, Ghabra, Nora, Joshi, Nishtha, Fitch, Eryn, Helbig, Katherine L, McKnight, Dianalee, Lindy, Amanda S, Zou, Fanggeng, Helbig, Ingo, Cooper, Edward C, George, Jr, Alfred L

“…Hundreds of genetic variants in KCNQ2 encoding the voltage-gated potassium channel KV7.2 are associated with early onset epilepsy and/or developmental…”
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Orc6 is a component of the replication fork and enables efficient mismatch repair by Lin, Yo-Chuen, Liu, Dazhen, Chakraborty, Arindam, Kadyrova, Lyudmila Y, Song, You Jin, Hao, Qinyu, Mitra, Jaba, Hsu, Rosaline Y C, Arif, Mariam K, Adusumilli, Sneha, Liao, Ting-Wei, Ha, Taekjip, Kadyrov, Farid A, Prasanth, Kannanganattu V, Prasanth, Supriya G

“…Significance Origin recognition complex (ORC) is required for the initiation of DNA replication. Unlike other ORC components, the role of human Orc6 in…”
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Transportation-related Environmental Mixtures and Diabetes Prevalence and Control in Urban/Metropolitan Counties in the United States by Weiss, Margaret C, Adusumilli, Sneha, Jagai, Jyotsna S, Sargis, Robert M

“…Abstract Diabetes rates in the United States are staggering and climbing. Importantly, traditional risk factors fail to completely account for the magnitude of…”
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