Search Results - "Adriano de Paula Sabino"
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Recent advances in point of care testing for COVID-19 detection
Published in Biomedicine & pharmacotherapy (01-09-2022)“…The World Health Organizations declaration of the COVID-19 pandemic was a milestone for the scientific community. The high transmission rate and the huge…”
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Dysfunctional phenotype of systemic and pulmonary regulatory T cells associate with lethal COVID‐19 cases
Published in Immunology (01-04-2023)“…Severe cases of COVID‐19 present hyperinflammatory condition that can be fatal. Little is known about the role of regulatory responses in SARS‐CoV‐2 infection…”
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Evaluation of acute toxicity and in vitro antitumor activity of a novel doxorubicin-loaded folate-coated pH-sensitive liposome
Published in Biomedicine & pharmacotherapy (01-09-2023)“…Doxorubicin (DOX) loaded liposomes have been used and studied in the last decades due to the significant decrease in DOX induced cardiac and systemic toxicity…”
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4
Synthesis and cytotoxic evaluation of heterocyclic compounds by vinylic substitution of ketene dithioacetals
Published in Chemical biology & drug design (01-07-2024)“…N‐heterocyclic compounds are important molecular scaffolds in the search for new drugs, since most drugs contain heterocyclic moieties in their molecular…”
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SARS-CoV-2 Omicron BA.1, BA.2, and XAG identification during routine surveillance on a university campus in Belo Horizonte, Brazil, 2022
Published in Brazilian journal of microbiology (01-12-2022)“…We report SARS-CoV-2 genomic surveillance results between Belo Horizonte, Brazil’s third and fourth case waves. Samples were obtained through a routine…”
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6
Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection
Published in eLife (23-07-2020)“…Chronic ethanol consumption is a leading cause of mortality worldwide, with higher risks to develop pulmonary infections, including infections. Mechanisms…”
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7
Extreme lymphocytosis in a dog with T-zone lymphoma
Published in Open veterinary journal (Tripoli, Libya) (01-12-2023)“…Canine T-zone lymphoma (TZL) is recognized as an indolent CD45-T cell lymphoma, with low aggressiveness and high overall survival. The diagnosis is obtained by…”
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PHYTOCHEMICAL AND BIOLOGICAL STUDIES OF CONSTITUENTS FROM ROOTS OF Salacia crassifolia (CELASTRACEAE)
Published in Química Nova (01-05-2020)“…Salacia crassifolia traditionally known as “Bacupari-do-Cerrado” is used to treat kidney problems, and as a healing agent for coughs and malaria. The…”
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Synthetic 3-alkylpyridine alkaloid analogues as a new scaffold against leukemic cell lines: cytotoxic evaluation and mode of action
Published in Medicinal chemistry research (01-09-2019)“…Leukemia is a malignant disease that originates in the bone marrow, local of blood cells production. Chemotherapy treatment is one of the alternatives to…”
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Myelodysplastic neoplasms: An overview on diagnosis, risk-stratification, molecular pathogenesis, and treatment
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Myelodysplastic neoplasms are clonal hematological malignancies arising from hematopoietic stem cells that accumulate various mutations. MDS is heterogeneous…”
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Apolipoprotein E and PAI-1 gene polymorphisms and no association with arterial ischemic stroke and peripheral arterial disease manifestations
Published in Jornal brasileiro de patologia e medicina laboratorial (01-06-2018)“…ABSTRACT Introduction: Arterial thrombosis is considered a multifactorial disease, resulting from the interaction of genetic and acquired risk factors…”
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Troponin as a cardiotoxicity marker in breast cancer patients receiving anthracycline-based chemotherapy: A narrative review
Published in Biomedicine & pharmacotherapy (01-11-2018)“…•cTn with different cardiac biomarkers can contribute to the early diagnosis of cardiotoxicity.•Low cTn levels is related to a better outcome with a good…”
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13
Toxicological study of a new doxorubicin-loaded pH-sensitive liposome: A preclinical approach
Published in Toxicology and applied pharmacology (01-08-2018)“…Doxorubicin (DOX) is widely used in cancer treatment, however, the use of this drug is often limited due to its cardiotoxic side effects. In order to avoid…”
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14
An Approach for Engineering Peptides for Competitive Inhibition of the SARS-COV-2 Spike Protein
Published in Molecules (Basel, Switzerland) (01-04-2024)“…SARS-CoV-2 is the virus responsible for a respiratory disease called COVID-19 that devastated global public health. Since 2020, there has been an intense…”
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Tocotrienols-enriched Self-nanoemulsifying Drug Delivery System Enhances the Antileukemic Activity of All-trans Retinoic Acid but not Electrocardiogram Alterations Evoked by Its Combination with Arsenic Trioxide
Published in AAPS PharmSciTech (14-03-2023)“…All- trans retinoic acid and arsenic trioxide are the leading choices for the treatment of acute promyelocytic leukemia. Notwithstanding the impressive…”
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Gumprecht shadows: when to use this terminology?
Published in Jornal brasileiro de patologia e medicina laboratorial (01-10-2013)“…The expression Gumprecht shadows historically refers to lymphocyte lysates commonly observed in patients with chronic lymphocytic leukemia (CLL). A literature…”
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New Cardiovascular Biomarkers in Breast Cancer Patients Undergoing Doxorubicin-Based Chemotherapy
Published in Arquivos brasileiros de cardiologia (01-12-2023)“…Central Illustration : New Cardiovascular Biomarkers in Breast Cancer Patients Undergoing Doxorubicin-Based Chemotherapy. Cardiovascular diseases (CVDs) are…”
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microRNA miR-133a as a Biomarker for Doxorubicin-Induced Cardiotoxicity in Women with Breast Cancer: A Signaling Pathway Investigation
Published in Cardiovascular toxicology (01-07-2022)“…Cardiovascular toxicity is the main adverse effect of Doxorubicin (DOX) in cancer patients. microRNAs (miRNAs) are promising biomarkers to identify cardiac…”
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Correction: de Almeida et al. Acute Promyelocytic Leukemia (APL): A Review of the Classic and Emerging Target Therapies towards Molecular Heterogeneity. Future Pharmacol. 2023, 3, 162–179
Published in Future pharmacology (04-08-2023)“…In the original publication [...]…”
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RAP1-GTPase immunostaining is altered in human precancerous and cancerous cervical lesions
Published in Biomarkers in medicine (16-09-2024)“…This study investigated RAP1 immunostaining variation in different cell types during CC progression. Paraffin-embedded cervical tissues from 101 patients were…”
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