Search Results - "Adrian STURZA"
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The Renoprotective Mechanisms of Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i)-A Narrative Review
Published in International journal of molecular sciences (27-06-2024)“…Chronic kidney disease (CKD) is a noncommunicable condition that has become a major healthcare burden across the globe, often underdiagnosed and associated…”
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Identification of Resveratrol as Bioactive Compound of Propolis from Western Romania and Characterization of Phenolic Profile and Antioxidant Activity of Ethanolic Extracts
Published in Molecules (Basel, Switzerland) (16-09-2019)“…The present study aimed to assess the phenolic content of eight ethanolic propolis samples (P1-P8) harvested from different regions of Western Romania and…”
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Metformin alleviates monoamine oxidase-related vascular oxidative stress and endothelial dysfunction in rats with diet-induced obesity
Published in Molecular and cellular biochemistry (01-11-2021)“…In the past decade, monoamine oxidase (MAO) with 2 isoforms, MAO-A and B, has emerged as an important source of mitochondrial reactive oxygen species (ROS) in…”
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Impact of Dietary Restriction Regimens on Mitochondria, Heart, and Endothelial Function: A Brief Overview
Published in Frontiers in physiology (16-12-2021)“…Caloric restriction (CR) and intermittent fasting (IF) are strategies aimed to promote health beneficial effects by interfering with several mechanisms…”
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Liver and Pancreatic Toxicity of Endocrine-Disruptive Chemicals: Focus on Mitochondrial Dysfunction and Oxidative Stress
Published in International journal of molecular sciences (06-07-2024)“…In recent years, the worldwide epidemic of metabolic diseases, namely obesity, metabolic syndrome, diabetes and metabolic-associated fatty liver disease…”
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Monoamine Oxidases Are Mediators of Endothelial Dysfunction in the Mouse Aorta
Published in Hypertension (Dallas, Tex. 1979) (01-07-2013)“…Monoamine oxidases (MAOs) generate H2O2 as a by-product of their catalytic cycle. Whether MAOs are mediators of endothelial dysfunction is unknown and was…”
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Monoamine Oxidase Contributes to Valvular Oxidative Stress: A Prospective Observational Pilot Study in Patients with Severe Mitral Regurgitation
Published in International journal of molecular sciences (01-10-2024)“…Monoamine oxidases (MAOs), mitochondrial enzymes that constantly produce hydrogen peroxide (H O ) as a byproduct of their activity, have been recently…”
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The Off-Target Cardioprotective Mechanisms of Sodium-Glucose Cotransporter 2 Inhibitors: An Overview
Published in International journal of molecular sciences (14-07-2024)“…Sodium-glucose cotransporter 2 inhibitors (SGLT2i), a novel class of glucose-lowering drugs, have revolutionized the management of heart failure with reduced…”
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P2Y11 Agonism Prevents Hypoxia/Reoxygenation- and Angiotensin II-Induced Vascular Dysfunction and Intimal Hyperplasia Development
Published in International journal of molecular sciences (16-01-2021)“…Vascular dysfunction in cardiovascular diseases includes vasomotor response impairments, endothelial cells (ECs) activation, and smooth muscle cells (SMCs)…”
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Assessing the Relationship between Indexed Epicardial Adipose Tissue Thickness, Oxidative Stress in Adipocytes, and Coronary Artery Disease Complexity in Open-Heart Surgery Patients
Published in Medicina (Kaunas, Lithuania) (01-01-2024)“…: This cross-sectional study conducted at the Timișoara Institute of Cardiovascular Diseases, Romania, and the Centre for Translational Research and Systems…”
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Monoamine Oxidase (MAO) Is Expressed at the Level of Mitral Valve with Severe Regurgitation in Hypertrophic Obstructive Cardiomyopathy: A Case Report
Published in Medicina (Kaunas, Lithuania) (01-12-2022)“…Hypertrophic obstructive cardiomyopathy (HOCM) is one of the most common hereditary heart diseases. The severely hypertrophied interventricular septum combined…”
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Improvement of Platelet Respiration by Cell-Permeable Succinate in Diabetic Patients Treated with Statins
Published in Life (Basel, Switzerland) (28-03-2021)“…Diabetes mellitus (DM) is the most severe metabolic disease that reached the level of a global pandemic and is associated with high cardiovascular morbidity…”
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Metabolic Memory in Diabetes – Mechanistic Insights and the Impact of Cardiovascular Medication
Published in Revista română de cardiologie (01-09-2021)“…The prevalence of diabetes mellitus is increasing worldwide. Endothelial dysfunction plays a critical role in the pathophysiology of diabetes-related vascular…”
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Metformin Acutely Mitigates Oxidative Stress in Human Atrial Tissue: A Pilot Study in Overweight Non-Diabetic Cardiac Patients
Published in Life (Basel, Switzerland) (01-12-2022)“…Metformin, the first-line drug in type 2 diabetes mellitus, elicits cardiovascular protection also in obese patients via pleiotropic effects, among which the…”
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Monoamine oxidase inhibitors attenuate the vascular hyperglycemic memory in diabetic mice
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
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Assessment of dose-dependent vasculoprotective effects of aronia extracts in mice aorta
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
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Mitigation of monoamine oxidase-related endothelial dysfunction by antidiabetic medication in human mammary arteries
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
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Quercetin exerts an inhibitory effect on cellular bioenergetics of the B164A5 murine melanoma cell line
Published in Molecular and cellular biochemistry (01-10-2018)“…Modulation of mitochondrial bioenergetics and glycolysis in malignancies has recently emerged a potential chemotherapeutic strategy since numerous malignant…”
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Validation of Human Bone Marrow-derived Mesenchymal Stem Cells and MCF-7 Breast Cancer Cells Co-culture Using a 3D Perfused Biomimetic Microfluidic Platform
Published in Anticancer research (01-04-2024)“…Microfluidic experimental models allow to study the mutual interrelation between tumor development and the microvasculature avoiding animal use and lacking…”
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Methylene blue reduces monoamine oxidase expression and oxidative stress in human cardiovascular adipose tissue
Published in Molecular and cellular biochemistry (21-08-2024)“…Cardiovascular diseases represent the major cause of morbidity mainly due to chronic heart failure. Epicardial (EAT) and perivascular adipose tissues (PVAT)…”
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