Search Results - "Adrian, T.E"

Saffron-based crocin prevents early lesions of liver cancer: In vivo, in vitro and in silico analyses by Amin, A, Daoud, S, Zaki, N, Salehi-Ashtiani, K, Al-Hrout, A, Chaiboonchoe, A, Baig, B, Khazanehdari, K, Adrian, T.E

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Frondoside A enhances the antiproliferative effects of gemcitabine in pancreatic cancer by Al Shemaili, J, Mensah-Brown, E, Parekh, K, Thomas, S.A, Attoub, S, Hellman, B, Nyberg, F, Adem, A, Collin, P, Adrian, T.E

“…Abstract Pancreatic cancer has a very poor prognosis. While gemcitabine is the mainstay of therapy and improves quality of life, it has little impact on…”
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Studies on the mechanism of action of frondoside A in pancreatic cancer by Al Shemaili, J, Parekh, K, Thomas, S.A, Kelly, D.L, Ding, X.-Z, Attoub, S, Collin, S.P, Adrian, T.E

“…Knockdown of either MIC-1 or FABP3 using specific siRNA in AsPC-1 cells reversed the growth inhibitory effects of frondoside A. These findings suggest that…”
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Pharmacokinetics and comparative effects of frondosides in pancreatic cancer by Al Shemaili, J, Thomas, S.A, Ding, X.-Z, Newman, R.A, Attoub, S, Collin, S.P, Adrian, T.E

“…The present study compared the growth inhibitory effects of the three frondosides and their aglycone and related this to the pharmocokinetics and route of…”
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Human distribution and release of a putative new gut hormone, peptide YY by Adrian, T E, Ferri, G L, Bacarese-Hamilton, A J, Fuessl, H S, Polak, J M, Bloom, S R

“…A radioimmunoassay has been developed for the new intestinal hormonal peptide tyrosine tyrosine [peptide YY (PYY)]. Peptide YY concentrations were measured in…”
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Frondoside A potentiates the effects of conventional therapeutic agents in acute leukemia by Sajwani, F.H., Collin, P., Adrian, T.E.

“…[Display omitted] •Frondoside A markedly inhibits the proliferation of acute leukemia blast cells.•Acute T-lymphoblastic leukemia (CCRF-CEM) cells are very…”
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Effect of peptide YY on gastric, pancreatic, and biliary function in humans by Adrian, T E, Savage, A P, Sagor, G R, Allen, J M, Bacarese-Hamilton, A J, Tatemoto, K, Polak, J M, Bloom, S R

“…The effect of peptide YY (PYY) on gastric and pancreatico-biliary secretion was studied in humans. Peptide YY was infused into groups of 6 healthy volunteers…”
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Effects of exercise training on excitation–contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats by Salem, K. A., Qureshi, M. A., Sydorenko, V., Parekh, K., Jayaprakash, P., Iqbal, T., Singh, J., Oz, M., Adrian, T. E., Howarth, F. C.

“…Although, several novel forms of intervention aiming at newly identified therapeutic targets are currently being developed for diabetes mellitus (DM), it is…”
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The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart by Adrian, Thomas E., Oz, M., Parekh, K., Jayaprakash, P., Qureshi, M. A., Howarth, F. C., Dobrzynski, H.

“…Background. In vivo experiments in Goto-Kakizaki (GK) type 2 diabetic rats have demonstrated reductions in heart rate from a young age. The expression of genes…”
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Contractility of ventricular myocytes is well preserved despite altered mechanisms of [Ca.sup.2+] transport and a changing pattern of mRNA in aged type 2 Zucker diabetic fatty rat heart by Howarth, F.C, Qureshi, M.A, Hassan, Z, Isaev, D, Parekh, K, John, A, Oz, M, Raza, H, Adeghate, E, Adrian, T.E

“…There has been a spectacular rise in the global prevalence of type 2 diabetes mellitus and cardiovascular complications are the major cause of morbidity and…”
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Gastrointestinal and pancreatic hormones in the human fetus and mother at 18-21 weeks of gestation by Adrian, T E, Soltesz, G, MacKenzie, I Z, Bloom, S R, Aynsley-Green, A

“…Several gastrointestinal hormones appear to play an important developmental role in the newborn, particularly in preterm neonates. Although the cells producing…”
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Effects of peptide YY and neuropeptide Y on gastric emptying in man by Allen, J M, Fitzpatrick, M L, Yeats, J C, Darcy, K, Adrian, T E, Bloom, S R

“…Neuropeptide Y (NPY) and peptide YY (PYY) are two structurally related peptides. PYY has been identified within endocrine cells and NPY within nerves of the…”
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Regional distribution of bombesin and seven other regulatory peptides in the human brain by Ghatei, M A, Bloom, S R, Langevin, H, McGregor, G P, Lee, Y C, Adrian, T E, O'Shaughnessy, D J, Blank, M A, Uttenthal, L O

“…In order to compare within the same brains the quantitative distributions of a range of neuropeptides, bombesin, N- and C-terminal glucagon, cholecystokinin,…”
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ON THE MECHANISM OF TPA-INDUCED GROWTH ARREST IN PANCREATIC CANCER CELLS by Salabat, M.R., Ding, X.Z., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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APIGENIN INHIBITS HUMAN PANCREATIC CANCER CELL PROLIFERATION THROUGH G2/M CELL CYCLE ARREST by Ujiki, M.B., Ding, X.Z., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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Resveratrol inhibits pancreatic cancer cell proliferation through transcriptional induction of macrophage inhibitory cytokine-1 (MIC-1) by Golkar, L., Ding, X., Ujiki, M.B., Salabat, R.M., Bentrem, D.J., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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Oxidation/reduction of methionine residues in CCK: a study by radioimmunoassay and isocratic reverse phase high pressure liquid chromatography by Bacarese-Hamilton, A J, Adrian, T E, Chohan, P, Antony, T, Bloom, S R

“…The study was undertaken to investigate the oxidation and reduction of cholecystokinin (CCK) both as pure standards and as endogenous porcine peptides…”
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CHANGES IN EXPRESSION OF CELL CYCLE-ASSOCIATED GENES ACCOMPANY RETINOIC ACID-INDUCED GROWTH ARREST IN PANCREATIC CANCER CELLS by Singh, B., Roginsky, A., Ding, X.-Z., Murphy, R.F., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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REGULATION OF P21WAF1 TURNOVER BY RETINOIC ACID IN PANCREATIC CANCER CELLS by Singh, B., Roginsky, A., Ding, X.-Z., Murphy, R.F., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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SPROUTY2 EXPRESSION IN HUMAN PANCREATIC CANCER CELLS AND CHARACTERIZATION OF THE SPROUTY2 PROMOTER by Chan, C.Y., Burley, U., Ding, X.Z., Talamonti, M.S., Bell, R.H., Adrian, T.E.

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