Search Results - "Adragna, Norma C."

K-Cl cotransporters, cell volume homeostasis, and neurological disease by Kahle, Kristopher T, Khanna, Arjun R, Alper, Seth L, Adragna, Norma C, Lauf, Peter K, Sun, Dandan, Delpire, Eric

“…Highlights • KCCs have roles in the nervous system beyond modulating GABAergic signaling. • KCCs regulate nervous system cell volume, and are mutated in…”
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Assessment of Silver-Nanoparticles-Induced Erythrocyte Cytotoxicity through Ion Transport Studies by Adragna, Norma C, Alla, Praveen K, Pavel-Sizmore, Ioana E, Paluri, Arathi S L, Yaklic, Jerome, Lauf, Peter K

“…Silver nanoparticles (AgNPs) are the most frequently used nanomaterials in industrial and biomedical applications. Their functionalization significantly…”
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SERS of Human Red Blood Cells in Non-Resonant Conditions: Benefits, Limitations, and Complementary Tools (CytoViva and GFAAS) by Wells, Kelsey L, Alla, Praveen K, Kaiser, Kyra G, Murgulet, Ioana T, Adragna, Norma C, Pavel, Ioana E

“…Herein, Raman and surface-enhanced Raman spectroscopies (SERS) were successfully employed to establish the chemical interactions of citrate-capped silver…”
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Sea Water Acidification Affects Osmotic Swelling, Regulatory Volume Decrease and Discharge in Nematocytes of the Jellyfish Pelagia noctiluca by Morabito, Rossana, Marino, Angela, Lauf, Peter K., Adragna, Norma C., La Spada, Giuseppa

“…Background: Increased acidification/P CO2 of sea water is a threat to the environment and affects the homeostasis of marine animals. In this study, the effect…”
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Canonical Bcl-2 Motifs of the Na+/K+ Pump Revealed by the BH3 Mimetic Chelerythrine: Early Signal Transducers of Apoptosis? by Lauf, Peter K., Heiny, Judith, Meller, Jarek, Lepera, Michael A., Koikov, Leonid, Alter, Gerald M., Brown, Thomas L., Adragna, Norma C.

“…Background/Aims: Chelerythrine [CET], a protein kinase C [PKC] inhibitor, is a prop-apoptotic BH3-mimetic binding to BH1-like motifs of Bcl-2 proteins. CET…”
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Surface-Enhanced Raman Spectroscopy (SERS) Tracking of Chelerythrine, a Na+/K+ Pump Inhibitor, into Cytosol and Plasma Membrane Fractions of Human Lens Epithelial Cell Cultures by Dorney, Kevin M., Sizemore, Ioana E.P., Alqahtani, Tariq, Adragna, Norma C., Lauf, Peter K.

“…Background/Aims: The quaternary benzo-phenanthridine alkaloid (QBA) chelerythrine (CET) is a pro-apoptotic drug and Na + /K + pump (NKP) inhibitor in human…”
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Kinetic studies of K-Cl cotransport in cultured rat vascular smooth muscle cells by Lauf, Peter K, Sharma, Neelima, Adragna, Norma C

“…During aging, and development of atherosclerosis and cardiovascular disease (CVD), aortic vascular smooth muscle cells (VSMCs) transition from healthy…”
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Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak by Lauf, Peter K, Alqahtani, Tariq, Flues, Karin, Meller, Jaroslaw, Adragna, Norma C

“…In silico analysis predicts interaction between Na-K-ATPase (NKA) and Bcl-2 protein canonical BH3- and BH1-like motifs, consistent with NKA inhibition by the…”
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Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension by Orlov, S N, Adragna, N C, Adarichev, V A, Hamet, P

“…Data obtained during the last two decades show that spontaneously hypertensive rats, an acceptable experimental model of primary human hypertension, possess…”
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Regulation of potassium transport in human lens epithelial cells by Lauf, Peter K., Warwar, Ronald, Brown, Thomas L., Adragna, Norma C.

“…The major K influx pathways and their response to thiol modification by N-ethylmaleimide (NEM) and protein kinase and phosphatase inhibitors were characterized…”
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Homocysteine: to measure or not to measure? Focus on "functional NMDA receptors in rat erythrocytes" by Adragna, Norma C

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Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis by Adragna, Norma C, Ravilla, Nagendra B, Lauf, Peter K, Begum, Gulnaz, Khanna, Arjun R, Sun, Dandan, Kahle, Kristopher T

“…The defense of cell volume against excessive shrinkage or swelling is a requirement for cell function and organismal survival. Cell swelling triggers a…”
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Erythrocyte Signal Transduction Pathways, their Oxygenation Dependence and Functional Significance by Barvitenko, Nadezhda, Adragna, Norma, Weber, Roy

“…Erythrocytes play a key role in human and vertebrate metabolism. Tissue O 2 supply is regulated by both hemoglobin (Hb)-O 2 affinity and erythrocyte rheology,…”
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KCC2a Expression in a Human Fetal Lens Epithelial Cell Line by Lauf, Peter K., Di Fulvio, Mauricio, Srivastava, Vinita, Sharma, Neelima, Adragna, Norma C.

“…The fetal human lens epithelial cell (LEC) line (FHL124) possesses all four K + Cl - (KCC) cotransporter isoforms, KCC1-4, despite KCC2 being typically…”
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Apparent intermediate K conductance channel hyposmotic activation in human lens epithelial cells by Lauf, Peter K, Misri, Sandeep, Chimote, Ameet A, Adragna, Norma C

“…This study explores the nature of K fluxes in human lens epithelial cells (LECs) in hyposmotic solutions. Total ion fluxes, Na-K pump, Cl-dependent Na-K-2Cl…”
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Synopsis of the 48 annual meeting of the Lake Cumberland Biological Transport Group and the second biannual meeting of the Pendrin Consortium by Dossena, Silvia, Nofziger, Charity, Morabito, Rossana, Adragna, Norma C, Paulmichl, Markus

“…Ion transporters are the molecular basis for ion homeostasis of the cell and the whole organism. The anion exchanger pendrin is only one of a number of…”
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Ion transport in a human lens epithelial cell line exposed to hyposmotic and apoptotic stress by Chimote, Ameet A., Adragna, Norma C., Lauf, Peter K.

“…Membrane transport changes in human lens epithelial (HLE‐B3) cells under hyposmotic and apoptotic stress were compared. Cell potassium content, Ki, uptake of…”
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K-Cl cotransport: properties and molecular mechanism by Lauf, P K, Adragna, N C

“…K-Cl cotransport (COT), defined first in red blood cells as the Cl-dependent, ouabain-insensitive bidirectional K transport, encoded by at least four KCC…”
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Evidence for Aquaporin-mediated Water Transport in Nematocytes of the Jellyfish Pelagia noctiluca by Marino, Angela, Morabito, Rossana, La Spada, Giuseppina, Adragna, Norma C., Lauf, Peter K.

“…Nematocytes, the stinging cells of Cnidarians, have a cytoplasm confined to a thin rim. The main cell body is occupied by an organoid, the nematocyst,…”
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Synopsis of the 48th Annual Meeting of the Lake Cumberland Biological Transport Group and the Second Biannual Meeting of the Pendrin Consortium by Dossena, Silvia, Nofziger, Charity, Morabito, Rossana, Adragna, Norma C., Paulmichl, Markus

“…Ion transporters are the molecular basis for ion homeostasis of the cell and the whole organism. The anion exchanger pendrin is only one of a number of…”
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