Search Results - "Adlerz, K"
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Increasing yield of msc-evs in scalable xeno-free manufacturing
Published in Cytotherapy (Oxford, England) (01-05-2019)“…Background & AimExtracellular vesicles (EVs) are increasingly being investigated as both drug delivery vehicles and as a cell-free therapy. EVs from…”
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Successful technology transfer of a cgmp potency assay for an ancillary material to support cgmp stem cell manufacturing
Published in Cytotherapy (Oxford, England) (01-05-2018)Get full text
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Comparison of msc-evs manufatured in 2D versus scalable 3D bioreactor systems
Published in Cytotherapy (Oxford, England) (01-05-2019)“…Background & AimThere have been over 800 registered clinical trials using mesenchymal stem/stromal cells (MSCs) for therapeutic applications. Due to their…”
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Electrodeformation of multi-bilayer spherical concentric membranes by AC electric fields
Published in Europhysics letters (01-09-2017)“…It is now well established that external stresses alter the behaviour of cells, where such alterations can be as profound as changes in gene expression. A type…”
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Enhancing hMSC extracellular vesicle productivity with a novel collection media for scalable MSC-EV generation
Published in Cytotherapy (Oxford, England) (01-05-2021)Get full text
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Development of an optimized lentiviral transduction medium and process to manufacture genetically modified MSC working cell banks
Published in Cytotherapy (Oxford, England) (01-05-2021)Get full text
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Scalable manufacturing system for MSC-EV generation
Published in Cytotherapy (Oxford, England) (01-05-2020)“…Due to their potential as a key bioactive agent in regenerative medicine applications, MSC-derived extracellular vesicles (MSC-EVs) are increasingly being…”
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166 - Successful technology transfer of a cgmp potency assay for an ancillary material to support cgmp stem cell manufacturing
Published in Cytotherapy (Oxford, England) (01-05-2018)Get full text
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MINIMALLY INVASIVE TUMOR TISSUE PROCUREMENT IS FEASIBLE FOR CLINICAL MANUFACTURING OF OBX-115 ENGINEERED TUMOR-INFILTRATING LYMPHOCYTES (TIL)
Published in Cytotherapy (Oxford, England) (01-06-2024)“…TIL cell therapy is a promising investigational treatment for patients (pts) with advanced solid tumors. As an autologous adoptive T-cell therapy, a portion of…”
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A scalable and xeno-free bioreactor system for biomanufacturing of hUC-MSCs
Published in Cytotherapy (Oxford, England) (01-05-2020)“…Mesenchymal stem/stromal cells (MSCs) are a prominent cell type in cellular therapies with over 900 registered clinical trials. A critical bottleneck in using…”
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Evolving cardiac conduction phenotypes in developing zebrafish larvae: implications to drug sensitivity
Published in Zebrafish (01-12-2010)“…Cardiac arrhythmias include problems with impulse formation and/or conduction abnormalities. Zebrafish (Danio rerio) is an emerging model system for studying…”
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