Search Results - "Adler, William H"

The Mitogenic Effects of Endotoxin and Staphylococcal Enterotoxin B on Mouse Spleen Cells and Human Peripheral Lymphocytes by Peavy, Duane L, Adler, William H, Smith, Richard T

“…The effects of Salmonella endotoxin and staphylococcal enterotoxin B (SEB) were examined in vitro on mouse and human lymphocyte populations from unsensitized…”
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HIV infection and aging: mechanisms to explain the accelerated rate of progression in the older patient by Adler, William H, Baskar, Padmavathi V, Chrest, Francis J, Dorsey-Cooper, Barbara, Winchurch, Richard A, Nagel, James E

“…Age is an important predictor of progression in HIV infections. Not only do older individuals' develop AIDS more rapidly than younger persons, they die more…”
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Cytolytic activity of mitogen activated old and young mouse spleen cells against tumor target cells expressing high or low levels of Fas antigen by Saxena, R K, Adler, W H

“…Sensitivity of Fas expressing tumor cells (high levels in Hut78 & Jurkat; low levels in P815) toward the cytotoxic Con-A (5 microg/ml) activated spleen cells…”
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Immunoglobulin Heavy Chain Junctional Diversity in Young and Aged Humans by Xue, Wei, Luo, Shengyuan, Adler, William H, Schulze, Dan H, Berman, Jeffrey E

“…The causes of observed deficiencies in the humoral immune response in aged humans are unknown. Since a major source of antibody diversity is generated at the V…”
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Defective T-cell response in beige mutant mice by Saxena, Rajiv K, Saxena, Queen B, Adler, William H

“…Reports of a selective NK deficiency and normal T-cell function in C57BL/6 mice carrying the beige mutation (bg/bg) suggested that these mice might be useful…”
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Supplemental zinc (Zn2+) restores antibody formation in cultures of aged spleen cells. II. Effects on mediator production by Winchurch, R A, Togo, J, Adler, W H

“…In vitro antibody production to T-dependent erythrocyte antigens is depressed as a function of age. Supplementation of antibody-forming cultures with the…”
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Spontaneous or natural killer cytotoxicity of K562 erythroleukemic cells in normal patients by Nagel, J E, Collins, G D, Adler, W H

“…Peripheral blood mononuclear cells from 200 normal individuals, ages 20 to 95 years, were evaluated for their capability to mediate spontaneous or natural…”
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Age differences in phagocytosis by polymorphonuclear leukocytes measured by flow cytometry by Nagel, J E, Han, K, Coon, P J, Adler, W H, Bender, B S

“…Elderly persons have increased morbidity and mortality due to bacterial infections. Since the polymorphonuclear leukocyte (PMN) is a major defense against…”
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Role of Cyclic Adenosine 3',5'-Monophosphate in Lymphocyte Mitogenesis by DeRubertis, Frederick R, Zenser, Terry V, Adler, William H, Hudson, Thomas

“…For assessment of the role of cyclic adenosine 3′,5′-monophosphate (cAMP) in lymphocyte mitogenesis, adenylate cyclase activity, cAMP content, 3H-thymidine…”
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Pretreatment of Murine Thymocytes by Phytohemagglutinin Inhibits the Binding of 3H-Concanavalin A by Ozato, Keiko, Ebert, James D, Adler, William H

“…The binding of 3H-concanavalin A (Con A) to cortisone-resistant and normal mouse thymocytes, which greatly differ in mitogenic responsiveness, was compared…”
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The Quantitative Production of Interferon by Mitogen-Stimulated Mouse Lymphocytes as a Function of Age and Its Effect on the Lymphocytes Proliferative Response by Heine, Jochen W, Adler, William H

“…Interferon production by mitogen-stimulated mouse spleen cells increases as the age of the cell donor increases and also varies with with the strain of the…”
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Mitogenicity of Bacterial Endotoxins: Characterization of the Mitogenic Principle by Peavy, Duane L, Shands, Joseph W., Jr, Adler, William H, Smith, Richard T

“…Endotoxins from smooth strains of Salmonella typhimurium and from rough variants of Ra, Rc and Re chemotype were mitogenic for mouse spleen cells. Haptenic…”
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Effect of Age upon Primary Alloantigen Recognition by Mouse Spleen Cells by Adler, William H, Takiguchi, Tomoo, Smith, Richard T

“…The response of spleen cells from three mouse strains, C57BL/6 CBA and A/J, to alloantigenic stimulation in mixed cell cultures was studied throughout the…”
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The Kinetics of Interferon Production by Mouse Lymphocytes and Its Modulating Effect on the Virus Plaque-Forming Cell Assay As a Quantitative Method to Determine Activated Lymphocytes by Heine, Jochen W, Adler, William H

“…The validity of the virus plaque-forming cell (V-PFC) assay as a means to quantitate stimulated mouse T cells is dependent on the rate and amount of coinciding…”
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Identification of HIV-1 envelope glycoprotein in the serum of AIDS and ARC patients by Oh, S K, Cruikshank, W W, Raina, J, Blanchard, G C, Adler, W H, Walker, J, Kornfeld, H

“…Binding of the human immunodeficiency virus type 1 (HIV-1) external envelope glycoprotein (gp120) has been reported to alter the function and surface antigen…”
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Human tumor immunity by Smith, R T, Adler, W H

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Age-related effects in T cell activation and proliferation by Song, L, Kim, Y H, Chopra, R K, Proust, J J, Nagel, J E, Nordin, A A, Adler, W H

“…Age-associated thymic involution manifests its effects in a variety of ways that are related to a loss of T cell function. These include the appearance of a…”
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In Vitro erythrocidal activity of activated spleen cells from young and old mice by Saxena, Rajiv K., Adler, William H.

“…We have recently reported that activated mouse spleen mononuclear cells (MNCs) efficiently lyse autologous erythrocytes in vitro (Saxena and Chandrasekhar,…”
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Epstein-Barr virus infection in a child with acquired immunodeficiency syndrome by Fackler, J C, Nagel, J E, Adler, W H, Mildvan, P T, Ambinder, R F

“…A 3-year-old girl, born to an intravenous-drug-dependent mother, had protracted diarrhea, failure to thrive, generalized lymphadenopathy, and recurrent fevers…”
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Acquired immunodeficiency syndrome in the elderly by Adler, W H, Nagel, J E

“…Recent data from the US show that since 1990 the number of paediatric patients with AIDS is decreasing while the number of patients with AIDS over age 50 years…”
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